Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ite A Offringa"'
Autor:
Matthew D Gregory, Kweku Ofosu-Asante, Jassy Mary S Lazarte, Pablo E Puente, Nada Tawfeeq, Nadine Belony, Yong Huang, Ite A Offringa, Nazarius S Lamango
Publikováno v:
PLoS ONE, Vol 19, Iss 10, p e0312563 (2024)
KRAS mutations are the most common oncogenic mutations in lung adenocarcinoma in Black Americans. Polyisoprenylated Cysteinyl amide Inhibitors (PCAIs) constitute a group of potential cancer therapy agents that we designed to specifically disrupt and
Externí odkaz:
https://doaj.org/article/162c4ca0528449b8afb30f6d38461cf8
Autor:
Daniel J Mullen, Chunli Yan, Diane S Kang, Beiyun Zhou, Zea Borok, Crystal N Marconett, Peggy J Farnham, Ite A Offringa, Suhn Kyong Rhie
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009023 (2020)
Lung cancer is the leading cause of cancer-related death and lung adenocarcinoma is its most common subtype. Although genetic alterations have been identified as drivers in subsets of lung adenocarcinoma, they do not fully explain tumor development.
Externí odkaz:
https://doaj.org/article/692a71ce835c4814b88eb6d01cb57628
Autor:
Sungshim L. Park, Yesha M. Patel, Lenora W. M. Loo, Daniel J. Mullen, Ite A. Offringa, Alika Maunakea, Daniel O. Stram, Kimberly Siegmund, Sharon E. Murphy, Maarit Tiirikainen, Loïc Le Marchand
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Lung cancer is the leading cause of cancer-related death. While cigarette smoking is the primary cause of this malignancy, risk differs across racial/ethnic groups. For the same number of cigarettes smoked, Native Hawaiians compar
Externí odkaz:
https://doaj.org/article/67c88d458b6545b0886b02eff2c43a85
Autor:
Masafumi Horie, Alessandra Castaldi, Mitsuhiro Sunohara, Hongjun Wang, Yanbin Ji, Yixin Liu, Fan Li, Thomas A. Wilkinson, Long Hung, Hua Shen, Hidenori Kage, Ite A. Offringa, Crystal N. Marconett, Per Flodby, Beiyun Zhou, Zea Borok
Publikováno v:
Cells, Vol 9, Iss 11, p 2460 (2020)
Molecular and functional characterization of alveolar epithelial type I (AT1) cells has been challenging due to difficulty in isolating sufficient numbers of viable cells. Here we performed single-cell RNA-sequencing (scRNA-seq) of tdTomato+ cells fr
Externí odkaz:
https://doaj.org/article/ce2fcf11018c4b0d9564c1d239275256
Autor:
Jianxin Shi, Xing Hua, Bin Zhu, Sarangan Ravichandran, Mingyi Wang, Cu Nguyen, Seth A Brodie, Alessandro Palleschi, Marco Alloisio, Gianluca Pariscenti, Kristine Jones, Weiyin Zhou, Aaron J Bouk, Joseph Boland, Belynda Hicks, Adam Risch, Hunter Bennett, Brian T Luke, Lei Song, Jubao Duan, Pengyuan Liu, Takashi Kohno, Qingrong Chen, Daoud Meerzaman, Crystal Marconett, Ite Laird-Offringa, Ian Mills, Neil E Caporaso, Mitchell H Gail, Angela C Pesatori, Dario Consonni, Pier Alberto Bertazzi, Stephen J Chanock, Maria Teresa Landi
Publikováno v:
PLoS Medicine, Vol 13, Iss 12, p e1002162 (2016)
BACKGROUND:Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer and has a high risk of distant metastasis at every disease stage. We aimed to characterize the genomic landscape of LUAD and identify mutation signatures assoc
Externí odkaz:
https://doaj.org/article/30013d5f9ba74edfbd73493a4b002027
Autor:
Diego A. Velarde, Sarah A. Elmalh, Hannah Lee, Joseph Valdes, Matthew Gladstone, Ryan E. Dinigle, Martin Kast, Ite A. Offringa
Publikováno v:
Cancer Research. 83:4112-4112
Small cell lung cancer (SCLC) has a 95% mortality rate and a 5-year survival of 8%, resulting in the death of over 20,000 Americans each year. There has been marginal improvement in therapy over the past 30 years, with the recent addition of immune c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8119c16ae6df123db025f7ef42cdf40
https://doi.org/10.1158/1538-7445.am2023-4112
https://doi.org/10.1158/1538-7445.am2023-4112
Autor:
Debra E. Lyon, Diana J. Wilkie, John D. Carpten, Kinfe K. Redda, R. Renee Reams, Mariana C. Stern, Ite A. Offringa, Folakemi T. Odedina, Bereket Mochona
Publikováno v:
J Cancer Educ
Lack of substantive research experiences and technical skills mentoring during undergraduate studies leaves many Underrepresented Minority (URM) students unprepared to apply to competitive graduate programs. As a part of our ongoing effort to increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbad3a5c708222ac7c5d4a4263f2bad3
https://doi.org/10.1007/s13187-020-01762-w
https://doi.org/10.1007/s13187-020-01762-w
Autor:
Nadine L. Belony, Bing Ren, Phuc Pham, Matthew Gregory, Pablo E. Puente, Nazarius S. Lamango, Ite A. Offringa, Yong Huang
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:C024-C024
Lung cancer is one of the top five deadliest cancers, and Black Americans have a higher mortality rate when compared to White Americans. Lung adenocarcinoma (LUAD) is the most common histological lung cancer subtype in all population groups including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c7ecf0c904489956cfb9e86e29b2867
https://doi.org/10.1158/1538-7755.disp22-c024
https://doi.org/10.1158/1538-7755.disp22-c024
Autor:
Pablo E. Puente, Chunli Yan, Matthew Gregory, Nadine Belony, Nazarius Lamango, Yong Huang, Ite A. Offringa
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:A087-A087
Lung cancer is a source of racial disparity among Black Americans, especially men. Despite lower tobacco exposure among Black men than White men, Black men are 37% more likely to develop lung cancer. Lung adenocarcinoma (LUAD) is the most common subt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5472d180b3fd0365551fdd4c1c7e49c
https://doi.org/10.1158/1538-7755.disp22-a087
https://doi.org/10.1158/1538-7755.disp22-a087
Autor:
Matthew D. Gregory, Pablo E. Puente, Nadine L. Belony, Jassy Mary S. Lazarte, Nada Tawfeeq, Yong Huang, Ite A. Offringa, Nazarius S. Lamango
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:C022-C022
KRAS mutations are the most common oncogenic mutations in lung adenocarcinoma in Black Americans. Polyisoprenylated cysteinyl amide inhibitors (PCAIs) constitute a group of cancer therapy agents designed to specifically disrupt and suppress hyperacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20114835576f14e1b03ada9364680b6a
https://doi.org/10.1158/1538-7755.disp22-c022
https://doi.org/10.1158/1538-7755.disp22-c022