Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Ite A Offringa"'
Autor:
Matthew D Gregory, Kweku Ofosu-Asante, Jassy Mary S Lazarte, Pablo E Puente, Nada Tawfeeq, Nadine Belony, Yong Huang, Ite A Offringa, Nazarius S Lamango
Publikováno v:
PLoS ONE, Vol 19, Iss 10, p e0312563 (2024)
KRAS mutations are the most common oncogenic mutations in lung adenocarcinoma in Black Americans. Polyisoprenylated Cysteinyl amide Inhibitors (PCAIs) constitute a group of potential cancer therapy agents that we designed to specifically disrupt and
Externí odkaz:
https://doaj.org/article/162c4ca0528449b8afb30f6d38461cf8
Autor:
Christopher Leon, Eugene Manley, Aaron M. Neely, Jonathan Castillo, Michele Ramos Correa, Diego A. Velarde, Minxiao Yang, Pablo E. Puente, Diana I. Romero, Bing Ren, Wenxuan Chai, Matthew Gladstone, Nazarius S. Lamango, Yong Huang, Ite A. Offringa
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lung cancer is the leading cause of cancer death in the United States and worldwide, and a major source of cancer health disparities. Lung cancer cell lines provide key in vitro models for molecular studies of lung cancer development and progression,
Externí odkaz:
https://doaj.org/article/3c0b93895845427d88af1f284e5b5912
Autor:
R. Renee Reams, Folakemi T. Odedina, John D. Carpten, Kinfe Redda, Mariana C. Stern, Janice L. Krieger, Jose Aparicio, Brooke Hensel, Nissa Askins, Andre Abreu, Angela Adams, Edward Agyare, Jamel Ali, John M. Allen, Richard Aló, Lourdes Baezconde-Garbanati, Jason Brant, Clyde P. Brown, Sarah G. Buxbaum, Pinchas Cohen, Wendy Cozen, Miriam O. Ezenwa, Sara Falzarano, Roger B. Fillingim, Hernan Flores-Rozas, Kristianna M. Fredenburg, Thomas George, Bo Han, Yong Huang, Chanita Hughes Halbert, Gebre-Egziabher Kiros, Nazarius S. Lamango, Ji-Hyun Lee, Debra E. Lyon, Duane A. Mitchell, Bereket Mochona, Jorge J. Nieva, Ite A. Offringa, Paul Okunieff, Alexander Parker, Suhn K. Rhie, Joyce M. Richey, Sherise C. Rogers, Bodour Salhia, Thomas D. Schmittgen, Richard Segal, Veronica W. Setiawan, Ukamaka Smith, Li-Ming Su, Sandra Suther, Jose Trevino, Enrique I. Velazquez-Villarreal, Fern J. Webb, Anna H. Wu, Yingwei Yao, Diana J. Wilkie
Publikováno v:
Cancer Control, Vol 30 (2023)
Introduction The Florida-California Cancer Research, Education, and Engagement (CaRE 2 ) Health Equity Center is a triad partnership committed to increasing institutional capacity for cancer disparity research, the diversity of the cancer workforce,
Externí odkaz:
https://doaj.org/article/e983d5aca8ef44e3bcc7ae504f4e6bca
Autor:
Evelyn Tran, Tuo Shi, Xiuwen Li, Adnan Y. Chowdhury, Du Jiang, Yixin Liu, Hongjun Wang, Chunli Yan, William D. Wallace, Rong Lu, Amy L. Ryan, Crystal N. Marconett, Beiyun Zhou, Zea Borok, Ite A. Offringa
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103780- (2022)
Summary: Many acute and chronic diseases affect the distal lung alveoli. Alveolar epithelial cell (AEC) lines are needed to better model these diseases. We used de-identified human remnant transplant lungs to develop a method to establish AEC lines.
Externí odkaz:
https://doaj.org/article/14e27615e8a74d299c651d68643a0241
Autor:
Daniel J Mullen, Chunli Yan, Diane S Kang, Beiyun Zhou, Zea Borok, Crystal N Marconett, Peggy J Farnham, Ite A Offringa, Suhn Kyong Rhie
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009023 (2020)
Lung cancer is the leading cause of cancer-related death and lung adenocarcinoma is its most common subtype. Although genetic alterations have been identified as drivers in subsets of lung adenocarcinoma, they do not fully explain tumor development.
Externí odkaz:
https://doaj.org/article/692a71ce835c4814b88eb6d01cb57628
Autor:
Sungshim L. Park, Yesha M. Patel, Lenora W. M. Loo, Daniel J. Mullen, Ite A. Offringa, Alika Maunakea, Daniel O. Stram, Kimberly Siegmund, Sharon E. Murphy, Maarit Tiirikainen, Loïc Le Marchand
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Lung cancer is the leading cause of cancer-related death. While cigarette smoking is the primary cause of this malignancy, risk differs across racial/ethnic groups. For the same number of cigarettes smoked, Native Hawaiians compar
Externí odkaz:
https://doaj.org/article/67c88d458b6545b0886b02eff2c43a85
Autor:
Masafumi Horie, Alessandra Castaldi, Mitsuhiro Sunohara, Hongjun Wang, Yanbin Ji, Yixin Liu, Fan Li, Thomas A. Wilkinson, Long Hung, Hua Shen, Hidenori Kage, Ite A. Offringa, Crystal N. Marconett, Per Flodby, Beiyun Zhou, Zea Borok
Publikováno v:
Cells, Vol 9, Iss 11, p 2460 (2020)
Molecular and functional characterization of alveolar epithelial type I (AT1) cells has been challenging due to difficulty in isolating sufficient numbers of viable cells. Here we performed single-cell RNA-sequencing (scRNA-seq) of tdTomato+ cells fr
Externí odkaz:
https://doaj.org/article/ce2fcf11018c4b0d9564c1d239275256
Autor:
Diego A. Velarde, Sarah A. Elmalh, Hannah Lee, Joseph Valdes, Matthew Gladstone, Ryan E. Dinigle, Martin Kast, Ite A. Offringa
Publikováno v:
Cancer Research. 83:4112-4112
Small cell lung cancer (SCLC) has a 95% mortality rate and a 5-year survival of 8%, resulting in the death of over 20,000 Americans each year. There has been marginal improvement in therapy over the past 30 years, with the recent addition of immune c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8119c16ae6df123db025f7ef42cdf40
https://doi.org/10.1158/1538-7445.am2023-4112
https://doi.org/10.1158/1538-7445.am2023-4112
Autor:
Nadine L. Belony, Bing Ren, Phuc Pham, Matthew Gregory, Pablo E. Puente, Nazarius S. Lamango, Ite A. Offringa, Yong Huang
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:C024-C024
Lung cancer is one of the top five deadliest cancers, and Black Americans have a higher mortality rate when compared to White Americans. Lung adenocarcinoma (LUAD) is the most common histological lung cancer subtype in all population groups including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c7ecf0c904489956cfb9e86e29b2867
https://doi.org/10.1158/1538-7755.disp22-c024
https://doi.org/10.1158/1538-7755.disp22-c024
Autor:
Pablo E. Puente, Chunli Yan, Matthew Gregory, Nadine Belony, Nazarius Lamango, Yong Huang, Ite A. Offringa
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:A087-A087
Lung cancer is a source of racial disparity among Black Americans, especially men. Despite lower tobacco exposure among Black men than White men, Black men are 37% more likely to develop lung cancer. Lung adenocarcinoma (LUAD) is the most common subt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5472d180b3fd0365551fdd4c1c7e49c
https://doi.org/10.1158/1538-7755.disp22-a087
https://doi.org/10.1158/1538-7755.disp22-a087