Výsledky vyhledávání - "Ite A Laird-Offringa"

Akademický článek

Integrated transcriptomic and epigenomic analysis of primary human lung epithelial cell differentiation.

Autor: Crystal N Marconett, Beiyun Zhou, Megan E Rieger, Suhaida A Selamat, Mickael Dubourd, Xiaohui Fang, Sean K Lynch, Theresa Ryan Stueve, Kimberly D Siegmund, Benjamin P Berman, Zea Borok, Ite A Laird-Offringa

Publikováno v: PLoS Genetics, Vol 9, Iss 6, p e1003513 (2013)

Elucidation of the epigenetic basis for cell-type specific gene regulation is key to gaining a full understanding of how the distinct phenotypes of differentiated cells are achieved and maintained. Here we examined how epigenetic changes are integrat

Externí odkaz: https://doaj.org/article/e2949e16647a4913ad4616b7b0a203ad

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Akademický článek

DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.

Autor: Suhaida A Selamat, Janice S Galler, Amit D Joshi, M Nicky Fyfe, Mihaela Campan, Kimberly D Siegmund, Keith M Kerr, Ite A Laird-Offringa

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21443 (2011)

BackgroundAberrant DNA methylation is common in lung adenocarcinoma, but its timing in the phases of tumor development is largely unknown. Delineating when abnormal DNA methylation arises may provide insight into the natural history of lung adenocarc

Externí odkaz: https://doaj.org/article/b2eb146cafaf44aa9752ec800a46f547

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Akademický článek

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.

Autor: Mihaela Campan, Melissa Moffitt, Sahar Houshdaran, Hui Shen, Martin Widschwendter, Günter Daxenbichler, Tiffany Long, Christian Marth, Ite A Laird-Offringa, Michael F Press, Louis Dubeau, Kimberly D Siegmund, Anna H Wu, Susan Groshen, Uma Chandavarkar, Lynda D Roman, Andrew Berchuck, Celeste L Pearce, Peter W Laird

Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28141 (2011)

The identification of sensitive biomarkers for the detection of ovarian cancer is of high clinical relevance for early detection and/or monitoring of disease recurrence. We developed a systematic multi-step biomarker discovery and verification strate

Externí odkaz: https://doaj.org/article/9afcd7d731f74b27b24783aea1f95de5

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Supplementary Table and Figure Legends from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival

Legends for Supplementary Tables S1-S5 and Supplementary Figures S1-S2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fcfabd80b5fc4cb5d6c91b47551e8a
https://doi.org/10.1158/0008-5472.22406730.v1

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Supplementary Table S4 from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival

Supplementary Table S4. Aggressive hybrid protein signature and gene ontology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3645320df7739377aa52b6960a0c0c
https://doi.org/10.1158/0008-5472.22406736

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Supplementary Figure S1 from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival

Supplementary Figure S1. Background information for lung adenocarcinoma cell lines.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e9f0e5aa9f1ea08ca189a18646d46d
https://doi.org/10.1158/0008-5472.22406754

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Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

Autor: Jason Y.Y. Wong, Han Zhang, Chao A. Hsiung, Kouya Shiraishi, Kai Yu, Keitaro Matsuo, Maria Pik Wong, Yun-Chul Hong, Jiucun Wang, Wei Jie Seow, Zhaoming Wang, Minsun Song, Hee Nam Kim, I-Shou Chang, Nilanjan Chatterjee, Wei Hu, Chen Wu, Tetsuya Mitsudomi, Wei Zheng, Jin Hee Kim, Adeline Seow, Neil E. Caporaso, Min-Ho Shin, Lap Ping Chung, She-Juan An, Ping Wang, Yang Yang, Hong Zheng, Yasushi Yatabe, Xu-Chao Zhang, Young Tae Kim, Qiuyin Cai, Zhihua Yin, Young-Chul Kim, Bryan A. Bassig, Jiang Chang, James Chung Man Ho, Bu-Tian Ji, Yataro Daigo, Hidemi Ito, Yukihide Momozawa, Kyota Ashikawa, Yoichiro Kamatani, Takayuki Honda, H. Dean Hosgood, Hiromi Sakamoto, Hideo Kunitoh, Koji Tsuta, Shun-ichi Watanabe, Michiaki Kubo, Yohei Miyagi, Haruhiko Nakayama, Shingo Matsumoto, Masahiro Tsuboi, Koichi Goto, Jianxin Shi, Lei Song, Xing Hua, Atsushi Takahashi, Akiteru Goto, Yoshihiro Minamiya, Kimihiro Shimizu, Kazumi Tanaka, Fusheng Wei, Fumihiko Matsuda, Jian Su, Yeul Hong Kim, In-Jae Oh, Fengju Song, Wu-Chou Su, Yu-Min Chen, Gee-Chen Chang, Kuan-Yu Chen, Ming-Shyan Huang, Li-Hsin Chien, Yong-Bing Xiang, Jae Yong Park, Sun-Seog Kweon, Chien-Jen Chen, Kyoung-Mu Lee, Batel Blechter, Haixin Li, Yu-Tang Gao, Biyun Qian, Daru Lu, Jianjun Liu, Hyo-Sung Jeon, Chin-Fu Hsiao, Jae Sook Sung, Ying-Huang Tsai, Yoo Jin Jung, Huan Guo, Zhibin Hu, Wen-Chang Wang, Charles C. Chung, Laurie Burdett, Meredith Yeager, Amy Hutchinson, Sonja I. Berndt, Wei Wu, Herbert Pang, Yuqing Li, Jin Eun Choi, Kyong Hwa Park, Sook Whan Sung, Li Liu, C.H. Kang, Meng Zhu, Chung-Hsing Chen, Tsung-Ying Yang, Jun Xu, Peng Guan, Wen Tan, Chih-Liang Wang, Michael Hsin, Ko-Yung Sit, James Ho, Ying Chen, Yi Young Choi, Jen-Yu Hung, Jun Suk Kim, Ho Il Yoon, Chien-Chung Lin, In Kyu Park, Ping Xu, Yuzhuo Wang, Qincheng He, Reury-Perng Perng, Chih-Yi Chen, Roel Vermeulen, Junjie Wu, Wei-Yen Lim, Kun-Chieh Chen, Yao-Jen Li, Jihua Li, Hongyan Chen, Chong-Jen Yu, Li Jin, Tzu-Yu Chen, Shih-Sheng Jiang, Jie Liu, Taiki Yamaji, Belynda Hicks, Kathleen Wyatt, Shengchao A. Li, Juncheng Dai, Hongxia Ma, Guangfu Jin, Bao Song, Zhehai Wang, Sensen Cheng, Xuelian Li, Yangwu Ren, Ping Cui, Motoki Iwasaki, Taichi Shimazu, Shoichiro Tsugane, Junjie Zhu, Kaiyun Yang, Gening Jiang, Ke Fei, Guoping Wu, Hsien-Chin Lin, Hui-Ling Chen, Yao-Huei Fang, Fang-Yu Tsai, Wan-Shan Hsieh, Jinming Yu, Victoria L. Stevens, Ite A. Laird-Offringa, Crystal N. Marconett, Linda Rieswijk, Ann Chao, Pan-Chyr Yang, Xiao-Ou Shu, Tangchun Wu, Y.L. Wu, Dongxin Lin, Kexin Chen, Baosen Zhou, Yun-Chao Huang, Takashi Kohno, Hongbing Shen, Stephen J. Chanock, Nathaniel Rothman, Qing Lan

Publikováno v: Genomics, 112(2), 1223. Academic Press Inc.
Genomics, 112(2), 1223-1232. Academic Press Inc.
Genomics

We investigated whether genetic susceptibility to tuberculosis (TB) influences lung adenocarcinoma development among never-smokers using TB genome-wide association study (GWAS) results within the Female Lung Cancer Consortium in Asia. Pathway analysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b3e9bd337a2961f1186b92ef9aec4d
https://doi.org/10.1016/j.ygeno.2019.07.008

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Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers

Autor: Jubao Duan, Theresa Ryan Stueve, William Wheeler, Neil E. Caporaso, Maria Teresa Landi, Zea Borok, Tongwu Zhang, Xing Hua, Jianxin Shi, Wen-Qing Li, Ite A. Laird-Offringa, Chenchen Yang, Crystal N. Marconett, Angela Cecilia Pesatori, Daniel J. Mullen, Chunli Yan, Beiyun Zhou

Publikováno v: Human Molecular Genetics. 26:3014-3027

Smoking-associated DNA hypomethylation has been observed in blood cells and linked to lung cancer risk. However, its cause and mechanistic relationship to lung cancer remain unclear. We studied the association between tobacco smoking and epigenome-wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4aaa6a13989011bdd0528e6fc298c4
https://doi.org/10.1093/hmg/ddx188

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An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription

Autor: David W. Crawford, Brett D. Blakeley, Chringma Sherpa, Ite A. Laird-Offringa, Po-Han Chen, Stuart F.J. Le Grice, Brian R. McNaughton

Publikováno v: ACS Chemical Biology. 11:2206-2215

Potent and selective recognition and modulation of disease-relevant RNAs remains a daunting challenge. We previously examined the utility of the U1A N-terminal RNA recognition motif as a scaffold for tailoring new RNA hairpin recognition, and showed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a99a014f57fde355429101d7c8c2e1
https://doi.org/10.1021/acschembio.6b00145

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Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs

Publikováno v: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Vannini, I; Wise, PM; Challagundla, KB; Plousiou, M; Raffini, M; Bandini, E; et al.(2018). Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.. Nature communications, 9(1), 160. doi: 10.1038/s41467-017-02485-1. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/9bh2p48z

The transcribed ultraconserved regions (T-UCRs) encode long non-coding RNAs implicated in human carcinogenesis. Their mechanisms of action and the factors regulating their expression in cancers are poorly understood. Here we show that high expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884a81f89e2612f65bdb4b08869dd718
https://pubmed.ncbi.nlm.nih.gov/29180617

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