Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Itay Rousso"'
Autor:
Christopher Aiken, Itay Rousso
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-9 (2021)
Abstract The viral capsid plays a key role in HIV-1 reverse transcription. Recent studies have demonstrated that the small molecule IP6 dramatically enhances reverse transcription in vitro by stabilizing the viral capsid. Reverse transcription result
Externí odkaz:
https://doaj.org/article/12ccb4248d0048a1a28fbfa562175fef
Autor:
Eden Bergman, Riki Goldbart, Tamar Traitel, Eliz Amar‐Lewis, Jonathan Zorea, Ksenia Yegodayev, Irit Alon, Sanela Rankovic, Yuval Krieger, Itay Rousso, Moshe Elkabets, Joseph Kost
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 3, Pp n/a-n/a (2021)
Abstract We hypothesize that the biomechanical properties of cells can predict their viability, with Young's modulus representing the former and cell sensitivity to ultrasound representing the latter. Using atomic force microscopy, we show that the Y
Externí odkaz:
https://doaj.org/article/ceab88fde4af4b7d984e53b2f1feb13d
Autor:
Chaoyi Xu, Douglas K Fischer, Sanela Rankovic, Wen Li, Robert A Dick, Brent Runge, Roman Zadorozhnyi, Jinwoo Ahn, Christopher Aiken, Tatyana Polenova, Alan N Engelman, Zandrea Ambrose, Itay Rousso, Juan R Perilla
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3001015 (2020)
Reverse transcription, an essential event in the HIV-1 life cycle, requires deoxynucleotide triphosphates (dNTPs) to fuel DNA synthesis, thus requiring penetration of dNTPs into the viral capsid. The central cavity of the capsid protein (CA) hexamer
Externí odkaz:
https://doaj.org/article/1aa20b004af54e01aac2ef7867b6cf2f
Autor:
Itay Rousso, Akshay Deshpande
Publikováno v:
Viruses, Vol 14, Iss 3, p 648 (2022)
Obtaining an understanding of the mechanism underlying the interrelations between the structure and function of HIV-1 is of pivotal importance. In previous decades, this mechanism was addressed extensively in a variety of studies using conventional a
Externí odkaz:
https://doaj.org/article/d5ef2ba70ef8442a80887303375dbb53
Autor:
Chuang Liu, Juan R. Perilla, Jiying Ning, Manman Lu, Guangjin Hou, Ruben Ramalho, Benjamin A. Himes, Gongpu Zhao, Gregory J. Bedwell, In-Ja Byeon, Jinwoo Ahn, Angela M. Gronenborn, Peter E. Prevelige, Itay Rousso, Christopher Aiken, Tatyana Polenova, Klaus Schulten, Peijun Zhang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The host cell factor cyclophilin A (CypA) interacts with the HIV-1 capsid and regulates infectivity. Here the authors combine cryo-EM, solid-state NMR and all-atom MD simulations, identifying an interaction interface between CypA and the HIV capsid t
Externí odkaz:
https://doaj.org/article/3b563f433dd146d4b7f6b78da7c03c54
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109089 (2014)
Unique features of diatoms are their intricate cell covers (frustules) made out of hydrated, amorphous silica. The frustule defines and maintains cell shape and protects cells against grazers and pathogens, yet it must allow for cell expansion during
Externí odkaz:
https://doaj.org/article/232df940516747f2983bda74f39c6235
Autor:
Shimon Harel, Yarin Altaras, Dikla Nachmias, Noa Rotem-Dai, Inbar Dvilansky, Natalie Elia, Itay Rousso
Publikováno v:
Biophysical Journal. 121:4229-4238
The assembly and budding of newly formed human immunodeficiency virus-1 (HIV-1) particles occur at the plasma membrane of infected cells. Although the molecular basis for viral budding has been studied extensively, investigation of its spatiotemporal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d0d298c9890d339d0cd1cbd8ccc2fe
https://doi.org/10.1016/j.bpj.2022.08.035
https://doi.org/10.1016/j.bpj.2022.08.035
Autor:
Itay Rousso, Christopher Aiken
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-9 (2021)
Retrovirology
Retrovirology
The viral capsid plays a key role in HIV-1 reverse transcription. Recent studies have demonstrated that the small molecule IP6 dramatically enhances reverse transcription in vitro by stabilizing the viral capsid. Reverse transcription results in mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc9fab569bdaa0c84fb1d554f43d4bc
https://doaj.org/article/12ccb4248d0048a1a28fbfa562175fef
https://doaj.org/article/12ccb4248d0048a1a28fbfa562175fef
Autor:
Shimon Harel, Yarin Altaras, Dikla Nachmias, Noa Rotem-Dai, Inbar Segal, Natalie Elia, Itay Rousso
The assembly and budding of newly formed human immunodeficiency virus-1 (HIV-1) particles occur at the plasma membrane of infected cells. Whereas the molecular basis for viral budding has been studied extensively, investigation of its spatiotemporal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c140a345f875113977cbdd7920ede3f
https://doi.org/10.1101/2021.12.12.472262
https://doi.org/10.1101/2021.12.12.472262
Autor:
Tamar Traitel, Eliz Amar-Lewis, Sanela Rankovic, Riki Goldbart, Eden Bergman, Itay Rousso, Moshe Elkabets, Irit Alon, Joseph Kost, Yuval Krieger, Ksenia M. Yegodayev, Jonathan Zorea
Publikováno v:
Bioengineering & Translational Medicine
Bioengineering & Translational Medicine, Vol 6, Iss 3, Pp n/a-n/a (2021)
Bioengineering & Translational Medicine, Vol 6, Iss 3, Pp n/a-n/a (2021)
We hypothesize that the biomechanical properties of cells can predict their viability, with Young's modulus representing the former and cell sensitivity to ultrasound representing the latter. Using atomic force microscopy, we show that the Young's mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c1128c29072f534cd57fe0300cd79a
http://europepmc.org/articles/PMC8459597
http://europepmc.org/articles/PMC8459597