Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Itaru Arai"'
Autor:
Gen Shiihashi, Daisuke Ito, Itaru Arai, Yuki Kobayashi, Kanehiro Hayashi, Shintaro Otsuka, Kazunori Nakajima, Michisuke Yuzaki, Shigeyoshi Itohara, Norihiro Suzuki
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 102-115 (2017)
Cytoplasmic aggregation of fused in sarcoma (FUS) is detected in brain regions affected by amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which compose the disease spectrum, FUS proteinopathy. To understand the pathomechanism
Externí odkaz:
https://doaj.org/article/21f55a5a95824160853cd1245012d7a4
Autor:
Sho Wakayama, Shigeki Kiyonaka, Itaru Arai, Wataru Kakegawa, Shinji Matsuda, Keiji Ibata, Yuri L. Nemoto, Akihiro Kusumi, Michisuke Yuzaki, Itaru Hamachi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Visualizing neurotransmitter receptor traffic is fundamental to understanding brain functions, but the current imaging methods can compromise the process. Here, the authors synthesize small fluorescent probes to label endogenous glutamate receptors i
Externí odkaz:
https://doaj.org/article/7eea3380bd2546d2924bb2c3f664fc62
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 723-736 (2017)
GABAergic synapses in brain circuits generate inhibitory output signals with submillisecond latency and temporal precision. Whether the molecular identity of the release sensor contributes to these signaling properties remains unclear. Here, we exami
Externí odkaz:
https://doaj.org/article/cb80837f50354dcd8a0d3458028144c5
Autor:
Itaru Arai, Peter Jonas
Publikováno v:
eLife, Vol 3 (2014)
A puzzling property of synaptic transmission, originally established at the neuromuscular junction, is that the time course of transmitter release is independent of the extracellular Ca2+ concentration ([Ca2+]o), whereas the rate of release is highly
Externí odkaz:
https://doaj.org/article/e4e9eebff6f84f5280587fd5b0bc8339
Autor:
Hiroshi Nonaka, Seiji Sakamoto, Kazuki Shiraiwa, Mamoru Ishikawa, Tomonori Tamura, Kyohei Okuno, Takumi Kondo, Shigeki Kiyonaka, Susaki, Etsuo A., Chika Shimizu, Ueda, Hiroki R., Wataru Kakegawa, Itaru Arai, Michisuke Yuzaki, Itaru Hamachi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/6/2024, Vol. 121 Issue 6, p1-12, 69p
Autor:
Hiroshi Nonaka, Seiji Sakamoto, Kazuki Shiraiwa, Mamoru Ishikawa, Tomonori Tamura, Kyohei Okuno, Shigeki Kiyonaka, Etsuo A. Susaki, Chika Shimizu, Hiroki R. Ueda, Wataru Kakegawa, Itaru Arai, Michisuke Yuzaki, Itaru Hamachi
Neurotransmitter receptors are essential components of synapses for communication between neurons in the brain. Because the spatiotemporal expression profiles and dynamics of neurotransmitter receptors involved in many functions are delicately govern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47ba0b2db53e3176244fee81d4a7f3ee
https://doi.org/10.1101/2023.01.16.524180
https://doi.org/10.1101/2023.01.16.524180
Autor:
Yuri L. Nemoto, Michisuke Yuzaki, Keiji Ibata, Itaru Hamachi, Shigeki Kiyonaka, Shinji Matsuda, Akihiro Kusumi, Itaru Arai, Sho Wakayama, Wataru Kakegawa
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The location and number of neurotransmitter receptors are dynamically regulated at postsynaptic sites. However, currently available methods for visualizing receptor trafficking require the introduction of genetically engineered receptors into neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87cdfb6d05c2a5cec611d8dc1100096
https://doi.org/10.1038/ncomms14850
https://doi.org/10.1038/ncomms14850
Publikováno v:
Journal of Orthopaedic Science
Background Pregabalin is a well-accepted treatment option for patients with neuropathic pain. However, the therapeutic efficacy of pregabalin for reducing the incidence of spinal surgery to treat leg symptoms in patients with lumbar spinal stenosis r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3deecfc20640ad1d3e6773dd60220d02
https://doi.org/10.1007/s00776-014-0642-z
https://doi.org/10.1007/s00776-014-0642-z
Autor:
Itaru Arai, Naoto Takahashi, Takahiro Kaga, Hironari Fukuda, Satoru Kayama, Kenji Ichiji, Shinichi Konno
Publikováno v:
Fukushima Journal of Medical Science. 60(1):35-42
The purpose of this study was to evaluate the therapeutic efficacy of pregabalin in patients with leg symptoms due to lumbar spinal stenosis. Study subjects were classified into two groups according to their pharmacotherapy: the pregabalin group, tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658451c7c58c4060bed1357e35a63475
http://ir.fmu.ac.jp/dspace/handle/123456789/401
http://ir.fmu.ac.jp/dspace/handle/123456789/401
Autor:
Satoru Kayama, Junichi Handa, Kenji Ichiji, Naoto Takahashi, Hironari Fukuda, Shinichi Konno, Itaru Arai
Publikováno v:
FUKUSHIMA JOURNAL OF MEDICAL SCIENCE. 60:175-180
A 22-year-old woman presented with complaints of severe pain in a wide region of the thoracolumbar spine. She developed severe pain in the thoracolumbar spine region 2 months after her first delivery and was referred 1 month later. A lateral thoracic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cfe97712b892542954e4798477eabf
https://doi.org/10.5387/fms.2014-14
https://doi.org/10.5387/fms.2014-14