Výsledky vyhledávání - "Itaru Anraku"

Akademický článek

Circulating heat shock protein 60 levels are elevated in HIV patients and are reduced by anti-retroviral therapy.

Autor: Itaru Anraku, Reena Rajasuriar, Caroline Dobbin, Richard Brown, Sharon R Lewin, Andreas Suhrbier

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e45291 (2012)

Circulating heat shock protein 60 (Hsp60) and heat shock protein 10 (Hsp10) have been associated with pro- and anti-inflammatory activity, respectively. To determine whether these heat shock proteins might be associated with the immune activation see

Externí odkaz: https://doaj.org/article/32ec56bf66c7476e9a2a12667fd22848

Zobrazit plný text záznamu

SerpinB2 Deficiency Results in a Stratum Corneum Defect and Increased Sensitivity to Topically Applied Inflammatory Agents

Autor: Thiago Dominguez Crespo Hirata, Itaru Anraku, Thuy T. Le, Lee Major, Jonathan Ellis, Andreas Suhrbier, Wayne A. Schroder, Helder I. Nakaya

Publikováno v: The American Journal of Pathology. 186:1511-1523

SerpinB2 (plasminogen activator inhibitor type 2) is constitutively expressed at high levels by differentiating keratinocytes in mice and humans; however, the physiological function of keratinocyte SerpinB2 remains unclear. Herein, we show that Serpi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f8e1e7895a32099e0dc35c477e5701
https://doi.org/10.1016/j.ajpath.2016.02.017

Zobrazit plný text záznamu

A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis

Autor: Danher Wang, Joy Gardner, Thuy T. Le, Adam Penn-Nicholson, Itaru Anraku, David Einfeld, John Y. Dong, Jan Woraratanadharm, Min Luo, Andreas Suhrbier, Michael Sakalian

Publikováno v: Vaccine. 29:2803-2809

Chikungunya virus, a mosquito-borne alphavirus, recently caused the largest epidemic ever seen for this virus. Chikungunya disease primarily manifests as a painful and debilitating arthralgia/arthritis, and no effective drug or vaccine is currently a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568ac09e033478e3e12597ebf8ee6e1d
https://doi.org/10.1016/j.vaccine.2011.01.108

Zobrazit plný text záznamu

Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virus

Autor: Wen J Liu, Christopher C. Pollitt, David C. Clark, Roy A. Hall, David C. Chang, Andreas Suhrbier, Alexander A. Khromykh, Itaru Anraku

Publikováno v: Nature Biotechnology. 26:571-577

DNA vaccines encoding replication-defective viruses are safer than inactivated or live attenuated viruses but may fail to stimulate an immune response sufficient for effective vaccination. We augment the protective capacity of a capsid-deleted flaviv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470883848e64ccacffe2471e279efe4e
https://doi.org/10.1038/nbt1400

Zobrazit plný text záznamu

Tetracycline-Inducible Packaging Cell Line for Production of Flavivirus Replicon Particles

Autor: Richard Linedale, Michael Jacobs, Itaru Anraku, Andreas Suhrbier, Xiang Ju Wang, Wen Jun Liu, Alexander A. Khromykh, Pei Yong Shi, Thuy T. Le, Andrew D. Davidson, Tracey J. Harvey

Publikováno v: Journal of Virology. 78:531-538

We have previously developed replicon vectors derived from the Australian flavivirus Kunjin that have a unique noncytopathic nature and have been shown to direct prolonged high-level expression of encoded heterologous genes in vitro and in vivo and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5e5655e62cc8c7755ece5e0eeb8592
https://doi.org/10.1128/jvi.78.1.531-538.2004

Zobrazit plný text záznamu

Kunjin Virus Replicon Vaccine Vectors Induce Protective CD8+T-Cell Immunity

Autor: Alexander A. Khromykh, Andreas Suhrbier, Richard Linedale, Tracey J. Harvey, Joy Gardner, Itaru Anraku, David Harrich

Publikováno v: Journal of Virology. 76:3791-3799

The ability of self-replicating RNA (replicon) vaccine vectors derived from the Australian flavivirus Kunjin (KUN) to induce protective αβ CD8+T-cell responses was examined. KUN replicons encoding a model immunogen were delivered by three different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c1abaedf4bfe8bded63b1c8b212de2
https://doi.org/10.1128/jvi.76.8.3791-3799.2002

Zobrazit plný text záznamu

Prime-boost vaccinations using recombinant flavivirus replicon and vaccinia virus vaccines: an ELISPOT analysis

Autor: Paweena Rattanasena, Thuy T. Le, Andreas Suhrbier, Joy Gardner, Alexander A. Khromykh, Itaru Anraku, Xiang Ju Wang

Publikováno v: Immunology and cell biology. 89(3)

Recombinant Kunjin replicon virus-like particle (VLP), vaccinia virus (rVV) and DNA vaccines were tested in a large series of prime-boost vaccinations using interferon (IFN)γ ELISPOT assays that reflected effector (E), effector memory (EM) and centr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b32719e205b4cef9fb74b9c8feb4a
https://pubmed.ncbi.nlm.nih.gov/20680025

Zobrazit plný text záznamu

Chikungunya virus arthritis in adult wild-type mice

Autor: Joy Gardner, Andreas Suhrbier, Thuy T. Le, Pierre Roques, Wayne A. Schroder, Stephen Higgs, Itaru Anraku, Thibaut Larcher, Lee Major

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2010, 84 (16), pp.8021-8032. ⟨10.1128/JVI.02603-09⟩
Journal of Virology, 2010, 84 (16), pp.8021-8032. ⟨10.1128/JVI.02603-09⟩

Chikungunya virus is a mosquito-borne arthrogenic alphavirus that has recently reemerged to produce the largest epidemic ever documented for this virus. Here we describe a new adult wild-type mouse model of chikungunya virus arthritis, which recapitu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463cd4217cca811ed564fb846e53ec52
https://hal.inrae.fr/hal-02663808

Zobrazit plný text záznamu

A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy

Autor: Thuy T. Le, Itaru Anraku, Wen Jun Liu, Gorben P. Pijlman, Leonie Smeenk, Xiang Ju Wang, Alexander A. Khromykh, Wayne A. Schroder, J. De Vrij, Andreas Suhrbier, Diem Hoang-Le

Publikováno v: Gene Therapy 16 (2009)
Gene Therapy, 16, 190-199

We have recently developed a non-cytopathic RNA replicon-based viral vector system based on the flavivirus Kunjin. Here, we illustrate the utility of the Kunjin replicon system for gene therapy. Intra-tumoral injections of Kunjin replicon virus-like

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea195652f171a29b8d5dbb6cd13c959a
https://research.wur.nl/en/publications/a-kunjin-replicon-vector-encoding-granulocyte-macrophage-colony-s

Zobrazit plný text záznamu

Kunjin virus replicon vectors for human immunodeficiency virus vaccine development

Autor: Richard Linedale, David Harrich, Andreas Suhrbier, Itaru Anraku, Jason M. Mackenzie, Alexander A. Khromykh, Tracey J. Harvey

Publikováno v: Journal of virology. 77(14)

We have previously demonstrated the ability of the vaccine vectors based on replicon RNA of the Australian flavivirus Kunjin (KUN) to induce protective antiviral and anticancer CD8 + T-cell responses using murine polyepitope as a model immunogen (I.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f72e71a91875d5731ae47eb058f8474
https://pubmed.ncbi.nlm.nih.gov/12829819

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání