Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Itamar Harel"'
Publikováno v:
eLife, Vol 12 (2023)
Pituitary hormones play a central role in shaping vertebrate life history events, including growth, reproduction, metabolism, and aging. The regulation of these traits often requires precise control of hormone levels across diverse timescales. Howeve
Externí odkaz:
https://doaj.org/article/494ad11d6b2346048c151a88925c73d4
Autor:
Itai Rozenberg, Tehila Atlan, Roman Franek, Eitan Moses, Adi Oron-Gottesman, Henrik Chrzanowski, Itamar Harel
Using lineage tracing and fate mapping strategies to study vertebrate aging has lagged behind developmental studies, primarily due to of the relatively long lifespans of classical models. Here, we introduce theKillibow, an inducible transgenic model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::babf99be009127e0352e74dd66c7ba33
https://doi.org/10.1101/2023.05.01.538839
https://doi.org/10.1101/2023.05.01.538839
Autor:
Eitan Moses, Itamar Harel
Fish display a remarkable diversity of life-history traits, including body size, age at maturity, and longevity. Although pituitary hormones are conserved mediators of life-history transitions, regulatory networks are less understood in fish. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd7786d0645fb43432b219a6e6c72c8d
https://doi.org/10.1101/2023.01.19.524675
https://doi.org/10.1101/2023.01.19.524675
Publikováno v:
Cold Spring Harbor protocols.
The African turquoise killifish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c74e75de2bea29ceb9cc8845a7b03d5
https://pubmed.ncbi.nlm.nih.gov/36223984
https://pubmed.ncbi.nlm.nih.gov/36223984
Autor:
Itamar Harel
Publikováno v:
Nature Methods. 19:1150-1151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025f4cb6b0d231c5d3d53f1c74235589
https://doi.org/10.1038/s41592-022-01631-y
https://doi.org/10.1038/s41592-022-01631-y
Autor:
Itamar Harel, Yiwen R. Chen, Inbal Ziv, Param Priya Singh, Paloma Navarro Negredo, Uri Goshtchevsky, Wei Wang, Gwendoline Astre, Eitan Moses, Andrew McKay, Ben E. Machado, Katja Hebestreit, Sifei Yin, Alejandro Sánchez Alvarado, Daniel F. Jarosz, Anne Brunet
SUMMARYProtein aggregation, which can sometimes spread in a prion-like manner, is a hallmark of neurodegenerative diseases. However, whether prion-like aggregates form during normal brain aging remains unknown. Here we use quantitative proteomics in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca9c6523399e065b414dcc28a0b4e91
https://doi.org/10.1101/2022.02.26.482115
https://doi.org/10.1101/2022.02.26.482115
Autor:
Yiwen R. Chen, Itamar Harel, Param Priya Singh, Inbal Ziv, Eitan Moses, Uri Goshtchevsky, Ben E. Machado, Anne Brunet, Daniel F. Jarosz
SUMMARYProtein aggregation is a hallmark of age-related neurodegeneration. Yet, aggregation during normal aging and in tissues other than the brain is poorly understood. Here we leverage the African turquoise killifish to systematically profile prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4801b64b4aadfb00af06964739ed47
https://doi.org/10.1101/2022.02.26.482120
https://doi.org/10.1101/2022.02.26.482120
Autor:
Gwendoline Astre, Tehila Atlan, Uri Goshtchevsky, Kobi Shapira, Adi Oron-Gottesman, Tomer Levy, Ariel Velan, Margarita Smirnov, Joris Deelen, Erez Y. Levanon, Itamar Harel
Energy homeostasis is disrupted with age, which then fuels multiple age-related pathologies. The AMP-activated protein kinase (AMPK) is the primary sensor of cellular energy in eukaryotes. However, the genetic regulation of vertebrate aging by AMPK r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de346cac127aa72307de112c75fcf0d8
https://doi.org/10.1101/2022.01.10.475524
https://doi.org/10.1101/2022.01.10.475524
Autor:
Claire Allen, Francesco Argenton, Gwendoline Astre, Diana P. Baumann, Filipek-Górniok Beata, John Bischof, Ellen Blaker, Ayelén M. Blanco, Radim Blažek, Marco Brocca, Livia D'Angelo, Paolo de Girolamo, Filippo Del Bene, Karine Duroure, Iva Dyková, Tim Ellis, Chika Fujimori, Robert Gerlai, Itamar Harel, Andrew Ingalls, Tokiro Ishikawa, Shinji Kanda, Ioanna Katsiadaki, Daichi Kayo, Kanav Khosla, Masato Kinoshita, Almut Köhler, Bräutigam Lars, Jean-Philippe Mocho, Eitan Moses, Yu Murakami, Mikoto Nakajo, Kiyoshi Naruse, Bruce Newell, Yoshitaka Oka, Jana Oltova, Nuno Pereira, Matej Polačik, Gokul Rajan, Martin Reichard, Paul Georg Schroeder, Marion Sebire, Natascia Tiso, Benjamin Tsang, Chie Umatani, Suraj Unniappan, Ana M. Valentim, Fredericus J. Van Eeden, Zoltán M. Varga, Jakub Žák
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c40be7b02fda0d42ad980b03bb59c0d3
https://doi.org/10.1016/b978-0-12-821099-4.01002-6
https://doi.org/10.1016/b978-0-12-821099-4.01002-6