Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Itamar Goren"'
Autor:
Sina Gonther, Malte Bachmann, Itamar Goren, Arnaud Huard, Andreas Weigert, Jörg Köhl, Heiko Mühl
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Murine acetaminophen-induced acute liver injury (ALI) serves as paradigmatic model for drug-induced hepatic injury and regeneration. As major cause of ALI, acetaminophen overdosing is a persistent therapeutic challenge with N-acetylcysteine
Externí odkaz:
https://doaj.org/article/e86f379873054c1d874f98dfc316986b
Autor:
Maximilian Lenz, Amelie Eichler, Pia Kruse, Andreas Strehl, Silvia Rodriguez-Rozada, Itamar Goren, Nir Yogev, Stefan Frank, Ari Waisman, Thomas Deller, Steffen Jung, Nicola Maggio, Andreas Vlachos
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic inflammation is associated with alterations in complex brain functions such as learning and memory. However, diagnostic approaches to functionally assess and quantify inflammation-associated alterations in synaptic plasticity are not well-es
Externí odkaz:
https://doaj.org/article/4b1cc1b96bce4d1ba4881e6c2efd1660
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168562 (2016)
Combined diabetes-obesity syndromes severely impair regeneration of acute skin wounds in mouse models. This study assessed the contribution of subcutaneous adipose tissue to exacerbated wound inflammatory conditions. Genetically obese (ob/ob) mice sh
Externí odkaz:
https://doaj.org/article/c48d2653ba52461090c73f3a9a047fbb
Autor:
Malte Bachmann, Katharina Horn, Ina Rudloff, Itamar Goren, Martin Holdener, Urs Christen, Nicole Darsow, Klaus-Peter Hunfeld, Ulrike Koehl, Peter Kind, Josef Pfeilschifter, Peter Kraiczy, Heiko Mühl
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001144 (2010)
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine s
Externí odkaz:
https://doaj.org/article/e6c088080be7423fa78c20ce81794829
Autor:
Khrystyna Sych, Simon P. Nold, Josef Pfeilschifter, Rajkumar Vutukuri, Jana Meisterknecht, Ilka Wittig, Stefan Frank, Itamar Goren
Publikováno v:
Journal of Molecular Medicine. 101:151-169
Abstract An injured skin is rapidly restored in a manner of wound healing. We have previously shown that intact insulin signaling and glucose uptake are fundamental to proper wound closure. Consequently, under exacerbated inflammation, compromised in
Autor:
null Simon P. Nold, null Khrystyna Sych, null Gergely Imre, null Dominik C. Fuhrmann, null Josef Pfeilschifter, null Rajkumar Vutukuri, null Frank Schnutgen, null Ilka Wittig, null Jana Meisterknecht, null Stefan Frank, null Itamar Goren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b999d0ff89825a2f383e00ac6ab381
https://doi.org/10.1111/febs.16625/v2/response1
https://doi.org/10.1111/febs.16625/v2/response1
Autor:
Steffen Jung, Amelie Eichler, Thomas Deller, Stefan Frank, Silvia Rodriguez-Rozada, Maximilian Lenz, Pia Kruse, Nicola Maggio, Ari Waisman, Andreas Vlachos, Itamar Goren, Nir Yogev, Andreas Strehl
Systemic inflammation is associated with alterations in complex brain functions such as learning and memory. However, diagnostic approaches to functionally assess and quantify inflammation-associated alterations in synaptic plasticity are not well-es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f1f01f866ae26eddd8037daf560676f
https://doi.org/10.1101/2020.10.16.336065
https://doi.org/10.1101/2020.10.16.336065
Publikováno v:
Nitric Oxide. 74:23-31
The gaseous mediator nitric oxide (NO) is a central regulatory molecule during the inflammatory phase of cutaneous tissue repair. The inducible NO-synthase (iNOS) represents the main isoform of the three NO producing enzymes at the wound site. In par
Publikováno v:
American Journal of Physiology-Renal Physiology. 312:F1044-F1055
Deficiency of cyclooxygenase-2 (COX-2) activity in the early postnatal period causes impairment of kidney development leading to kidney insufficiency. We hypothesize that impaired NaCl reabsorption during the first days of life is a substantial cause
Autor:
Stefan Frank, Seo-Youn Lee, Josef Pfeilschifter, Rolf M. Nüsing, Itamar Goren, Thomas Schlich, Damian Maucher
Publikováno v:
International Wound Journal. 14:53-63
Inhibition of cyclooxygenase (Cox) enzymatic activity by non-steroidal anti-inflammatory drugs (NSAIDs) provides the molecular basis of analgesia following wounding or surgery. This study investigated the role of Cox activity in the regulation of vas