Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Italo Faria do Valle"'
Autor:
Claudia Sala, Pietro Di Lena, Danielle Fernandes Durso, Italo Faria do Valle, Maria Giulia Bacalini, Daniele Dall’Olio, Claudio Franceschi, Gastone Castellani, Paolo Garagnani, Christine Nardini
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Introduction: DNA methylation clocks presents advantageous characteristics with respect to the ambitious goal of identifying very early markers of disease, based on the concept that accelerated ageing is a reliable predictor in this sense.Methods: Su
Externí odkaz:
https://doaj.org/article/0534b04076454726877ae0d8a3254bb8
Autor:
Mila Gugnoni, Eugenia Lorenzini, Italo Faria do Valle, Daniel Remondini, Gastone Castellani, Federica Torricelli, Elisabetta Sauta, Benedetta Donati, Moira Ragazzi, Francesco Ghini, Simonetta Piana, Alessia Ciarrocchi, Gloria Manzotti
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-12 (2023)
Abstract Anaplastic Thyroid Cancer (ATC) is the most aggressive and de-differentiated subtype of thyroid cancer. Many studies hypothesized that ATC derives from Differentiated Thyroid Carcinoma (DTC) through a de-differentiation process triggered by
Externí odkaz:
https://doaj.org/article/e983952e3be54fcdb0f46d506bbeff05
Autor:
Brian Ferolito, Italo Faria do Valle, Hanna Gerlovin, Lauren Costa, Juan P. Casas, J. Michael Gaziano, David R. Gagnon, Edmon Begoli, Albert-László Barabási, Kelly Cho
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Understanding the genetic relationships between human disorders could lead to better treatment and prevention strategies, especially for individuals with multiple comorbidities. A common resource for studying genetic-disease relationships is
Externí odkaz:
https://doaj.org/article/dbd109338c14435f91d75def3d6b5ff8
Autor:
Italo Faria do Valle, Brian Ferolito, Hanna Gerlovin, Lauren Costa, Serkalem Demissie, Franciel Linares, Jeremy Cohen, David R. Gagnon, J. Michael Gaziano, Edmon Begoli, Kelly Cho, Albert-László Barabási
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A better understanding of the sequential and temporal aspects in which diseases occur in patient’s lives is essential for developing improved intervention strategies that reduce burden and increase the quality of health services. Here we p
Externí odkaz:
https://doaj.org/article/d1a1df5fcb16439eb4d791e2f8c0f53e
Autor:
Jaquelline Carla Valamiel de Oliveira e Silva, Girley Francisco Machado de Assis, Maykon Tavares de Oliveira, Helder Magno Silva Valadares, Italo Faria do Valle, Nivia Carolina Nogueira de Paiva, Helen Rodrigues Martins, Marta de Lana
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 4, Pp 433-440 (2013)
Introduction The biological diversity of Trypanosoma cruzi strains plays an important role in the clinical and epidemiological features of Chagas disease. Methods Eight T. cruzi strains isolated from children living in a Chagas disease vector-control
Externí odkaz:
https://doaj.org/article/b6bb3965e9fe45b9b40a178dc44b0869
Autor:
Desiree Schenk, Rita Zhou, Olivia Petrillo, Alexis Mantilla, Italo Faria do Valle, Steven Maron, Brian S. Henick, Chih-Yi Liao, Daniel V.T. Catenacci, Sameek Roychowdhury, Benjamin Solomon, Alexander I. Spira, Ankur Dhanik, Andrew R. Fergusson, Karin Jooss, Matthew Davis
Publikováno v:
Cancer Research. 83:1126-1126
Therapeutic vaccines hold promise to broaden the potency of immune checkpoint blockade (ICB) therapy in tumors lacking immune reactivity. A heterologous chimpanzee adenovirus (ChAd68) and self-amplifying mRNA (samRNA)-based individualized neoantigen
Autor:
Marc Santolini, Michael L Sebek, Viatcheslav R. Akmaev, Helia N. Sanchez, Alex Jones, Feixiong Cheng, Joel M. Kremer, Mengran Wang, Asher Ameli, Italo Faria do Valle, Alif Saleh, Keith J. Johnson, Dimitrios A. Pappas, Theodore Mellors, Lixia Zhang, Jeffery R. Curtis, Johanna B. Withers, Susan Dina Ghiassian
Publikováno v:
Network and Systems Medicine. 3:91-104
Objectives: For rheumatoid arthritis (RA) patients failing to achieve treatment targets with conventional synthetic disease-modifying antirheumatic drugs, tumor necrosis factor (TNF)-α inhibitors (...
Autor:
Eugenia Lorenzini, Federica Torricelli, Raffaella Zamponi, Benedetta Donati, Veronica Manicardi, Elisabetta Sauta, Italo Faria do Valle, Francesca Reggiani, Mila Gugnoni, Gloria Manzotti, Valentina Fragliasso, Emanuele Vitale, Simonetta Piana, Valentina Sancisi, Alessia Ciarrocchi
Malignant pleural mesothelioma (MPM) is a rare and incurable cancer, which incidence is increasing in many countries. MPM escapes the classical genetic model of cancer evolution, lacking a distinctive genetic fingerprint. Omics profiling revealed ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c61026595f3c1258ad9a28a11116306
https://hdl.handle.net/11380/1290329
https://hdl.handle.net/11380/1290329
Autor:
Xiao Gan, Italo Faria do Valle, Marinka Zitnik, Asher Ameli, Rebecca M. Baron, Helia N. Sanchez, Dina Ghiassian, Albert-László Barabási, Joseph Loscalzo, Deisy Morselli Gysi, Onur Varol
Publikováno v:
ArXiv
Proceedings of the National Academy of Sciences of the United States of America
PNAS
Proceedings of the National Academy of Sciences of the United States of America
PNAS
Significance The COVID-19 pandemic has highlighted the importance of prioritizing approved drugs to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Here, we deployed algorithms relying on artificial intelligence, networ
Autor:
Hiroyuki Mori, Patrick T Keiser, Marinka Zitnik, Xiao Gan, Florence F. Wagner, Giulia Menichetti, Manu Anantpadma, Albert-László Barabási, Deborah J. Anderson, Robert A. Davey, Jacob Berrigan, Callie J Donahue, Suryaram Gummuluru, Italo Faria do Valle, Kirabo Tess Ayazika, Mark N. Namchuk, J. J. Patten, Sallieu Chernoh Jalloh, Joseph Loscalzo, Deisy Morselli Gysi, Kathleen Geoghegan-Barek, Seyoum Ayehunie
Publikováno v:
bioRxiv
The SARS-CoV-2 pandemic has caused widespread illness, loss of life, and socioeconomic disruption that is unlikely to resolve until vaccines are widely adopted, and effective therapeutic treatments become established. Here, a well curated and annotat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acd33f07b555b0c31288eb17d4a7e27
https://europepmc.org/articles/PMC8077576/
https://europepmc.org/articles/PMC8077576/