Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Italo, Mocchetti"'
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-4 (2019)
Abstract Aim The human-immunodeficiency virus (HIV) envelope protein gp120 promotes synaptic damage similar to that observed in people living with HIV who have neurocognitive disorders. The neurotoxic effect of gp120 appears to occur through the α-h
Externí odkaz:
https://doaj.org/article/956b049b38684c9d876563755a39a32b
Autor:
Valeria Avdoshina, Italo Mocchetti
Publikováno v:
Cells, Vol 11, Iss 10, p 1599 (2022)
Axonal degeneration and loss of synapses are often seen in different brain areas of people living with human immunodeficiency virus (HIV). Nevertheless, the underlying causes of the pathological alterations observed in these individuals are poorly co
Externí odkaz:
https://doaj.org/article/38281c59e5d54ecea5f62c83c23fed50
Autor:
Andrew Speidell, Gino Paolo Asuni, Valeria Avdoshina, Serena Scognamiglio, Patrick Forcelli, Italo Mocchetti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Activation of the p75 neurotrophin receptor (p75NTR), by the proneurotrophin brain-derived neurotrophic factor (proBDNF), triggers loss of synapses and promotes neuronal death. These pathological features are also caused by the human immunodeficiency
Externí odkaz:
https://doaj.org/article/087b2e3a5a0647c6aefb13841ba2f856
Autor:
Andrew Speidell, Sofia Walton, Lee A. Campbell, Francesco Tomassoni‐Ardori, Lino Tessarollo, Claudia Corbo, Francesca Taraballi, Italo Mocchetti
There are a number of G-protein-coupled receptors (GPCRs) that are considered “orphan receptors” because the information on their known ligands is incomplete. Yet, these receptors are important targets to characterize, as the discovery of their l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bde34bf400d3ce38bf903f8e6c162e6
https://hdl.handle.net/10281/412777
https://hdl.handle.net/10281/412777
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2018)
Chemokine (C-C motif) ligand 5 (CCL5) belongs to a group of chemokines that play a role in the peripheral immune system, mostly as chemoattractant molecules, and mediate tactile allodynia. In the central nervous system (CNS), CCL5 and its receptors h
Externí odkaz:
https://doaj.org/article/44cc500293bd4f4aa9505b2a14d05b67
Autor:
Lee A. Campbell, Italo Mocchetti
Publikováno v:
Neurotox Res
Extracellular vesicles are heterogeneous cell-derived membranous structures of nanometer size that carry diverse cargoes including nucleic acids, proteins, and lipids. Their secretion into the extracellular space and delivery of their cargo to recipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7f8b3087325bb3c4e9ef5c1c9542f5
https://doi.org/10.1007/s12640-021-00425-y
https://doi.org/10.1007/s12640-021-00425-y
Publikováno v:
Neurotoxicity Research. 39:1721-1731
Human immunodeficiency virus (HIV)-associated cognitive disorders (HAND) is characterized by impaired motor and intellectual functions, as well as mood disorders. Brain-derived neurotrophic factor and its receptor TrkB (or NTRK2) mediate the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::956495f614ca16156f0ff34c584514ac
https://doi.org/10.1007/s12640-021-00406-1
https://doi.org/10.1007/s12640-021-00406-1
Publikováno v:
Bio-Protocol, Vol 7, Iss 22 (2017)
Microglia and macrophage cells are the primary producers of cytokines in response to neuroinflammatory processes. But these cytokines are also produced by other glial cells, endothelial cells, and neurons. It is essential to identify the cells that p
Externí odkaz:
https://doaj.org/article/eb150b3422dd4dfcb85e439e381673ed
Publikováno v:
Handbook of Neurotoxicity ISBN: 9783031150791
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbda8bdf84895def8c8184d397f76e49
https://doi.org/10.1007/978-3-031-15080-7_230
https://doi.org/10.1007/978-3-031-15080-7_230
Autor:
Gaylia Jean Harry, Goulding Dr, Peter R. Mouton, Avdoshina, Andrew D. Kraft, Italo Mocchetti, Christopher A. McPherson
Publikováno v:
Neurotox Res
Animal models have been used to study cellular processes related to human immunodeficiency virus-1 (HIV-1)-associated neurocognitive disorders (HAND). The HIV-1 transgenic (Tg) rat expresses HIV viral genes except the gag-pol replication genes and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1676b2e18f4a2dc47a20316850a010a
https://doi.org/10.1007/s12640-019-00077-z
https://doi.org/10.1007/s12640-019-00077-z