Role of Chain Length and Degree of Unsaturation of Fatty Acids in the Physicochemical and Pharmacological Behavior of Drug-Fatty Acid Conjugates in Diabetes.

Autor: Singh AK; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani, Rajasthan 333031, India., Italiya KS; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani, Rajasthan 333031, India., Narisepalli S; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani, Rajasthan 333031, India., Chitkara D; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani, Rajasthan 333031, India., Mittal A; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani, Rajasthan 333031, India.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Oct 14; Vol. 64 (19), pp. 14217-14229. Date of Electronic Publication: 2021 Sep 28.

Nanoparticulate tablet dosage form of lisofylline-linoleic acid conjugate for type 1 diabetes: in situ single-pass intestinal perfusion (SPIP) studies and pharmacokinetics in rat.

Autor: Italiya KS; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani Campus, Pilani, Rajasthan, 333031, India., Singh AK; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani Campus, Pilani, Rajasthan, 333031, India., Chitkara D; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani Campus, Pilani, Rajasthan, 333031, India., Mittal A; Department of Pharmacy, Birla Institute of Technology and Science (BITS PILANI), Pilani Campus, Pilani, Rajasthan, 333031, India. anupama.mittal@pilani.bits-pilani.ac.in.

Publikováno v: AAPS PharmSciTech [AAPS PharmSciTech] 2021 Mar 24; Vol. 22 (3), pp. 114. Date of Electronic Publication: 2021 Mar 24.

Self-assembling lisofylline-fatty acid conjugate for effective treatment of diabetes mellitus.

Autor: Italiya KS; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan, India., Mazumdar S; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan, India., Sharma S; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan, India., Chitkara D; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan, India., Mahato RI; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, United States., Mittal A; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan, India. Electronic address: anupama.mittal@pilani.bits-pilani.ac.in.

Publikováno v: Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2019 Jan; Vol. 15 (1), pp. 175-187. Date of Electronic Publication: 2018 Oct 06.

Nanoparticulate-based drug delivery systems for small molecule anti-diabetic drugs: An emerging paradigm for effective therapy.

Autor: Uppal S; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan 333031, India., Italiya KS; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan 333031, India., Chitkara D; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan 333031, India., Mittal A; Department of Pharmacy, Birla Institute of Technology and Science (BITS-PILANI), Pilani, Rajasthan 333031, India. Electronic address: anupama.mittal@pilani.bits-pilani.ac.in.

Publikováno v: Acta biomaterialia [Acta Biomater] 2018 Nov; Vol. 81, pp. 20-42. Date of Electronic Publication: 2018 Sep 28.

Evaluation of oral pharmacokinetics, in vitro metabolism, blood partitioning and plasma protein binding of novel antidiabetic agent, S009-0629 in rats.

Autor: Valicherla GR; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India., Italiya KS; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Raebareli, India., Gupta CP; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Mishra S; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Riyazuddin M; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Syed AA; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Singh SK; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Shahi S; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Taneja G; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Wahajuddin M; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India., Goel A; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India., Gayen JR; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute (CDRI), Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.

Publikováno v: Drug development research [Drug Dev Res] 2018 Jun; Vol. 79 (4), pp. 173-183.