Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Istvan Zupko"'
Autor:
Nóra Szilvásy, Panna Lajer, Attila Horváth, Katalin Veres, Judit Hohmann, Zsuzsanna Schelz, Renáta Minorics, István Zupkó, Zsuzsanna Gáborik, Emese Kis, Csilla Temesszentandrási-Ambrus
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1363 (2024)
Background/Objectives: One of the major risks associated with the concomitant use of herbal products and therapeutic drugs is herb–drug interactions (HDIs). The most common mechanism leading to HDIs is the inhibition and/or induction of transport p
Externí odkaz:
https://doaj.org/article/4a40bb3573084d1fac430935c188ce42
Autor:
Mirela Nicolov, Roxana M. Ghiulai, Mirela Voicu, Marius Mioc, Adina Octavia Duse, Roxana Roman, Rita Ambrus, Istvan Zupko, Elena Alina Moaca, Dorina E. Coricovac, Claudia Farcas, Roxana Marcela Racoviceanu, Corina Danciu, Cristina-Adriana Dehelean, Codruta Soica
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Betulinic acid (BA) was demonstrated to be a very promising anticancer agent against various tumor cell lines such as breast, colon, lung, and brain. Despite its strong cytotoxic effect, betulinic acid exhibits low water solubility, feature that is r
Externí odkaz:
https://doaj.org/article/d56cf8c6e85e45c2a9cc26eead2d6cab
Autor:
Ionuţ Ledeţi, Ştefana Avram, Vasile Bercean, Gabriela Vlase, Titus Vlase, Adriana Ledeţi, Istvan Zupko, Marius Mioc, Lenuţa-Maria Şuta, Codruţa Şoica, Cristina Dehelean
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 22691-22702 (2015)
Betulonic acid belongs to the pentacyclic triterpenic derivative class and can be obtained through the selective oxidation of betulin. In this study we set obtaining several functionalized derivatives of this compound by its condensation with several
Externí odkaz:
https://doaj.org/article/f4d698d484ff4c7a977808e9af99b24f
Autor:
Corina Danciu, Codruta Soica, Cristina Dehelean, Istvan Zupko, Erzsebet Csanyi, Iulia Pinzaru
Publikováno v:
Analytical Cellular Pathology, Vol 2015 (2015)
The present study focuses on the synthesis and analysis of a genistein ester derivative with myristic acid followed by beta cyclodextrin encapsulation; physicochemical analysis using consecrated techniques such as FTIR, MS, DSC, and SEM revealed both
Externí odkaz:
https://doaj.org/article/58aa355df273480ca1fd868ceb20bdbe
Akademický článek
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Autor:
Iasmina Marcovici, Dorina Coricovac, Iulia Pinzaru, Ioana Gabriela Macasoi, Roxana Popescu, Raul Chioibas, Istvan Zupko, Cristina Adriana Dehelean
Publikováno v:
Cancers. 14(7)
Cancer poses an ongoing global challenge, despite the substantial progress made in the prevention, diagnosis, and treatment of the disease. The existing therapeutic methods remain limited by undesirable outcomes such as systemic toxicity and lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c5508693b69221bbd5aa4cce072551
https://pubmed.ncbi.nlm.nih.gov/35406610
https://pubmed.ncbi.nlm.nih.gov/35406610
Autor:
Mária Gáborová, Máté Vágvölgyi, Bizhar Ahmed Tayeb, Renáta Minorics, István Zupkó, Ondřej Jurček, Szabolcs Béni, Renata Kubínová, György Tibor Balogh, Attila Hunyadi
Publikováno v:
ACS Omega, Vol 9, Iss 16, Pp 18495-18504 (2024)
Externí odkaz:
https://doaj.org/article/7fbece91a8724e5fae69ba49cb526264
Autor:
Eszter Boglárka Lőrincz, Gergely Tóth, Júlia Spolárics, Mihály Herczeg, Jan Hodek, István Zupkó, Renáta Minorics, Dorottya Ádám, Attila Oláh, Christos C. Zouboulis, Jan Weber, Lajos Nagy, Eszter Ostorházi, Ildikó Bácskay, Anikó Borbás, Pál Herczegh, Ilona Bereczki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract (−)-Cannabidiol (CBD) and (−)-cannabigerol (CBG) are two major non-psychotropic phytocannabinoids that have many beneficial biological properties. However, due to their low water solubility and prominent first-pass metabolism, their oral
Externí odkaz:
https://doaj.org/article/5a9a372dc9b844a19bbb1a3fff919b53
Autor:
Muhammad Bello Saidu, Gordana Krstić, Petra Bombicz, Sourav De, Anita Barta, Hazhmat Ali, István Zupkó, Róbert Berkecz, Umar Shehu Gallah, Dóra Rédei, Judit Hohmann
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 907 (2024)
Monoterpene and 5-methylcoumarin- or 5-methylchromone-coupled meroterpenoids occurring mainly in the Asteraceae species proved to have high potency against protozoans, worms, and various tumor cells, which make them interesting targets for searching
Externí odkaz:
https://doaj.org/article/256959b53eac4bcfbbbf9f0fbed772df
Autor:
Nikoletta Szemerédi, Zsuzsanna Schelz, Dária Antónia Horvath, Bálint Rácz, András G. Szatmári, Hiba F. Muddather, Noémi Bózsity, István Zupkó, Gabriella Spengler
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 877 (2024)
Chemotherapy is a known treatment modality that improves the long-term survival of breast cancer patients. However, due to the resistance to numerous anticancer drugs, alternative chemotherapeutic strategies are required. Regarding antimetabolic drug
Externí odkaz:
https://doaj.org/article/9e6f2b925ffb49268430c49ee94d86f3