Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Istvan Teplan"'
Autor:
Istvan Teplan, Géza Tóth, Istvan Palyi, B. Vincze, Sándor Lovas, Magdolna Kovacs, I. Mezö, Richard F. Murphy, Judit Horvath
Publikováno v:
The Journal of Peptide Research. 52:384-389
In previous studies GnRH-III, a variant of the hypothalamic neurohormone GnRH, was isolated from the brain of the sea lamprey and structurally characterized. GnRH-III is a hypothalamic neurohormone in both female and male sea lampreys. In the present
Publikováno v:
International Journal of Peptide and Protein Research. 24:430-436
A photoreactive derivative of the highly potent gonadotropin releasing hormone (GnRH) agonist, D-Lys6-GnRH(1-9)-ethylamide, was prepared by selective modification of the epsilon-amino group with 2-nitro-4-azidophenyl sulfenyl chloride (2,4-NAPS C1).
Autor:
M. Idei, Edit Szabó, John M. Ostresh, György Kéri, Györgyi Bökönyi, Richard A. Houghten, Lászó Örfi, Ferenc Hollósy, Béla Szende, Istvan Teplan, Anikó Horváth
Publikováno v:
Journal of Peptide Science. 6:S191-S200
The aim of our work was to screen peptidomimetic tyrosine kinase inhibitory libraries for antiproliferative and apoptotic or necrotic effect. We also wanted to distinguish between cytostatic and cytotoxic activities.4-Benzylaminoquinasolines can be p
Autor:
Janos Seprodi, Borbála Vincze, Istvan Teplan, Melinda Móra, János Pató, Istvan Palyi, I. Mezö, Adrienn Kalnay
Publikováno v:
Journal of Bioactive and Compatible Polymers. 14:304-314
Gonadotropin releasing hormone (GnRH) is a decapeptide regulating the gonadotropin release in organisms. Its analogues inhibit breast, endometrium and prostatic tumor cell proliferation in vitro. Some analogues were conjugated via the lysine side cha
Autor:
B. Vincze, D. Gaál, I. Péter, Istvan Teplan, Gizella Turi, Adrienn Kalnay, I. Mezö, R. Mihalik, János Pató, Istvan Palyi, Sándor Lovas, Richard F. Murphy
Publikováno v:
Proceedings of the National Academy of Sciences. 96:2361-2366
Conjugation of gonadotropin-releasing hormone (GnRH) analogues GnRH-III, MI-1544, and MI-1892 through lysyl side chains and a tetrapeptide spacer, Gly-Phe-Leu-Gly (X) to a copolymer, poly( N -vinylpyrrolidone- co -maleic acid) (P) caused increased an
Autor:
József Kökösi, György Kéri, Laszlo Orfi, Istvan Teplan, György Szász, Marianna Mák, István Kövesdi
Publikováno v:
Bioorganic & Medicinal Chemistry. 4:547-551
1-Benzylidene (2-14) and 1-phenylhydrazono derivatives (15-29) of 3,4-dihydro-1H,6H-[1,4]oxazino[3,4-b]quinazolin-6-one (1) were obtained from the condensation reactions of 1 with a series of aromatic aldehydes and by direct diazonium coupling with a
Publikováno v:
Letters in Peptide Science. 2:339-344
We have found that guanidine acetate catalyses the transformation of a β-benzyl-aspartyl peptide (Boc-Asp-(OBzl)-Leu-Trp-OMe) to an aminosuccinyl peptide (Boc-Asu-Leu-Trp-OMe). The reaction was accompanied by partial epimerization. However, not even
Autor:
M. Idei, I. Mezö, Judit Érchegyi, Janos Seprodi, Anikó Horváth, Istvan Teplan, Zsolt Vadász, György Kéri
Publikováno v:
Electrophoresis. 17:758-761
Capillary electrophoresis (CE) and micellar electrokinetic chromatography (MEKC) methods, utilizing uncoated silica capillary and triethyl ammonium phosphate or sodium borate buffers in the pH range of 2.25–11.0, containing sodium dodecyl sulfate (
Publikováno v:
Neuroendocrinology. 59:371-379
We examined the desensitization and/or sensitization phenomenon in the pituitary GH responsiveness induced by continuous infusion and multiple pulses at different frequencies of a potent GH-RH analog [D-Ala2, Leu15, Nle27, GABA30-GH-RH(1–30)amide].
Autor:
Zsolt Vadász, G. Balogh, K. Y. Kumogaye, I. Schoen, N. Chino, A. Rill, Tamas Szirtes, Istvan Teplan, Shumpei Sakakibara, J. Seproedi
Publikováno v:
ChemInform. 23