Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Istvan Pirko"'
Autor:
Danielle N Renner, Fang Jin, Adam J Litterman, Alexis J Balgeman, Lisa M Hanson, Jeffrey D Gamez, Michael Chae, Brett L Carlson, Jann N Sarkaria, Ian F Parney, John R Ohlfest, Istvan Pirko, Kevin D Pavelko, Aaron J Johnson
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125565 (2015)
Glioblastoma (GBM) is among the most invasive and lethal of cancers, frequently infiltrating surrounding healthy tissue and giving rise to rapid recurrence. It is therefore critical to establish experimental model systems and develop therapeutic appr
Externí odkaz:
https://doaj.org/article/90232fcf3569472f97f5f1698045350b
Autor:
Holly L Johnson, Robin C Willenbring, Fang Jin, Whitney A Manhart, Stephanie J LaFrance, Istvan Pirko, Aaron J Johnson
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111401 (2014)
Numerous neurological disorders are characterized by central nervous system (CNS) vascular permeability. However, the underlying contribution of inflammatory-derived factors leading to pathology associated with blood-brain barrier (BBB) disruption re
Externí odkaz:
https://doaj.org/article/9d1b4ee84c704ae9adfaddf4340447f5
Autor:
Jan-Mendelt Tillema, Istvan Pirko
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 6 (2013)
Central nervous system inflammatory demyelinating disease can affect patients across the life span. Consensus definitions and criteria of all of the different acquired demyelinating diseases that fall on this spectrum have magnetic resonance imaging
Externí odkaz:
https://doaj.org/article/055b402c271444ec80889c52a93dacb0
Autor:
Istvan Pirko, Yi Chen, Anne K Lohrey, Jeremiah McDole, Jeffrey D Gamez, Kathleen S Allen, Kevin D Pavelko, Diana M Lindquist, R Scott Dunn, Slobodan I Macura, Aaron J Johnson
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31459 (2012)
MRI is sensitive to tissue pathology in multiple sclerosis (MS); however, most lesional MRI findings have limited correlation with disability. Chronic T1 hypointense lesions or "T1 black holes" (T1BH), observed in a subset of MS patients and thought
Externí odkaz:
https://doaj.org/article/62624d18afa148c58f91e3203c4c2c51
Autor:
Istvan Pirko, Rhonda Cardin, Yi Chen, Anne K Lohrey, Diana M Lindquist, R Scott Dunn, Robert Zivadinov, Aaron J Johnson
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32767 (2012)
Recent evidence in multiple sclerosis (MS) suggests that active CMV infection may result in more benign clinical disease. The goal of this pilot study was to determine whether underlying murine CMV (MCMV) infection affects the course of the Theiler's
Externí odkaz:
https://doaj.org/article/14c633209a9746139b2e53de79829582
Autor:
Aleksandar Denic, Slobodan I Macura, Arthur E Warrington, Istvan Pirko, Brandon R Grossardt, Larry R Pease, Moses Rodriguez
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26001 (2011)
Our laboratory demonstrated that a natural human serum antibody, sHIgM12, binds to neurons in vitro and promotes neurite outgrowth. We generated a recombinant form, rHIgM12, with identical properties. Intracerebral infection with Theiler's Murine Enc
Externí odkaz:
https://doaj.org/article/44ecd65ce2a7428083f505efb28aa427
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3037 (2008)
Disruption of the blood brain barrier (BBB) is a hallmark feature of immune-mediated neurological disorders as diverse as viral hemorrhagic fevers, cerebral malaria and acute hemorrhagic leukoencephalitis. Although current models hypothesize that imm
Externí odkaz:
https://doaj.org/article/89ef20abd59041fbb5eb6d8fe1524dff
This latest edition to the'Contemporary Neurology Series'will fill one of the few remaining'neurologic gaps'within the Series.'Multiple Sclerosis,'written solely by Moses Rodriguez, Orhun Kantarci and Istvan Pirko of the Mayo Clinic in Rochester, MN
Autor:
Imke Metz, Jay Mandrekar, Stephan Bramow, Nilufer Kale, Josa M. Frischer, Hans Lassmann, Yong Guo, Stephen D. Weigand, Joseph E. Parisi, Claudia F. Lucchinetti, Istvan Pirko, Wolfgang Brück
Publikováno v:
Annals of Neurology. 78:710-721
Objective An extensive analysis of white matter plaques in a large sample of multiple sclerosis (MS) autopsies provides insights into the dynamic nature of MS pathology. Methods One hundred twenty MS cases (1,220 tissue blocks) were included. Plaque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e6916013d60a4007628e7500a0ce7b1
https://doi.org/10.1002/ana.24497
https://doi.org/10.1002/ana.24497
Autor:
Istvan Pirko, M. Mateo Paz Soldan, Anne K. Lohrey, Jeffrey D. Gamez, Mekala R. Raman, Yi Chen, Aaron J. Johnson
Publikováno v:
Journal of Neuroimaging. 25:595-599
BACKGROUND Disability progression in multiple sclerosis (MS) remains incompletely understood. Unlike lesional measures, central nervous system atrophy has a strong correlation with disability. Theiler's murine encephalomyelitis virus infection in SJL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687e6f6332d578b785f5ecbf87d98d3e
https://doi.org/10.1111/jon.12250
https://doi.org/10.1111/jon.12250