Zobrazeno 1 - 10
of 82
pro vyhledávání: '"István M. Mándity"'
Publikováno v:
Cells, Vol 12, Iss 13, p 1700 (2023)
Every cell biological textbook teaches us that the main role of the plasma membrane is to separate cells from their neighborhood to allow for a controlled composition of the intracellular space. The mostly hydrophobic nature of the cell membrane pres
Externí odkaz:
https://doaj.org/article/4405036601e04ffd91fea8a87356a699
Autor:
Florina Zakany, Mate Szabo, Gyula Batta, Levente Kárpáti, István M. Mándity, Péter Fülöp, Zoltan Varga, Gyorgy Panyi, Peter Nagy, Tamas Kovacs
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Although the largely positive intramembrane dipole potential (DP) may substantially influence the function of transmembrane proteins, its investigation is deeply hampered by the lack of measurement techniques suitable for high-throughput examination
Externí odkaz:
https://doaj.org/article/98dcad6a7d124987944ec77cc7e79849
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 318-324 (2018)
The syntheses of various pyrimidinones as potentially bioactive products by means of the highly controlled continuous-flow retro-Diels–Alder reaction of condensed pyrimidinone derivatives are presented. Noteworthy, the use of this approach allowed
Externí odkaz:
https://doaj.org/article/9d87539bc7824fbda58dbd8043002aea
Autor:
András Gy. Németh, Renáta Szabó, György Orsy, István M. Mándity, György M. Keserű, Péter Ábrányi-Balogh
Publikováno v:
Molecules, Vol 26, Iss 2, p 303 (2021)
We have developed the continuous-flow synthesis of thioureas in a multicomponent reaction starting from isocyanides, amidines, or amines and sulfur. The aqueous polysulfide solution enabled the application of sulfur under homogeneous and mild conditi
Externí odkaz:
https://doaj.org/article/07e8637053364bfba6c73eb152c08028
Publikováno v:
Molecules, Vol 25, Iss 8, p 1985 (2020)
A continuous-flow acetylation reaction was developed, applying cheap and safe reagent, acetonitrile as acetylation agent and alumina as catalyst. The method developed utilizes milder reagent than those used conventionally. The reaction was tested on
Externí odkaz:
https://doaj.org/article/1d1d90260ad74ef0b4abcdd3cc68aefc
Autor:
Katalin Szilágyi, István Hajdú, Beáta Flachner, Zsolt Lőrincz, Júlia Balczer, Péter Gál, Péter Závodszky, Chiara Pirli, Balázs Balogh, István M. Mándity, Sándor Cseh, György Dormán
Publikováno v:
Molecules, Vol 24, Iss 20, p 3641 (2019)
The complement system is associated with various diseases such as inflammation or auto-immune diseases. Complement-targeted drugs could provide novel therapeutic intervention against the above diseases. C1s, a serine protease, plays an important role
Externí odkaz:
https://doaj.org/article/3ce5a0ddd5dc4f4ca2722c57e2d07a73
Publikováno v:
Journal of Mass Spectrometry. 57
Four fused nitrogen-containing ring systems were investigated by electrospray ionization-tandem mass spectrometry: Pyridazino-indoles, pyridazino-quinolines, a pyrimido-quinoline derivative and pyrimido-cinnolines. Fragmentation patterns of these com
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1508-1516 (2013)
The preparation of novel multi-substituted 1,2,3-triazole-modified β-aminocyclohexanecarboxylic acid derivatives in a simple and efficient continuous-flow procedure is reported. The 1,3-dipolar cycloaddition reactions were performed with copper powd
Externí odkaz:
https://doaj.org/article/31d4763fb84e4bf9aba928ae5ff1b95f
Autor:
Tamás Beke-Somfai, Tünde Juhász, Gitta Schlosser, Dóra Bogdán, András Wacha, István M. Mándity, Gergely Kohut, Imola Cs. Szigyártó, Ferenc Zsila, Vlada B. Urlacher, Zoltán Varga, Attila Bóta, Ferenc Fülöp, Judith Mihály
Publikováno v:
Chemical Science. 11:6868-6881
Self-assembling peptides offer a versatile set of tools for bottom-up construction of supramolecular biomaterials. Among these compounds, non-natural peptidic foldamers experience increased focus due to their structural variability and lower sensitiv
Publikováno v:
Catalysis Science & Technology. 10:7814-7818
Amide bonds are ubiquitous in nature. They can be found in proteins, peptides, alkaloids, etc. and they are used in various synthetic drugs too. Amide bonds are mainly made by the use of (i) hazardous carboxylic acid derivatives or (ii) expensive cou