Zobrazeno 1 - 10
of 86
pro vyhledávání: '"István Likó"'
Autor:
Orsolya Feró, Dóra Varga, Éva Nagy, Zsolt Karányi, Éva Sipos, József Engelhardt, Nóra Török, István Balogh, Borbála Vető, István Likó, Ábel Fóthi, Zoltán Szabó, Gábor Halmos, László Vécsei, Tamás Arányi, Lóránt Székvölgyi
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the death of motor neurons, the aetiology of which is essentially unknown. Here, we present an integrative epigenomic study in blood samples from seve
Externí odkaz:
https://doaj.org/article/f835840c5d2e4e40af2979ffd5e752d1
Autor:
Sára Pálla, Judit Tőke, Anikó Bozsik, Henriett Butz, János Papp, István Likó, Enikő Kuroli, András Bánvölgyi, Mátyás Hamar, Jerome Bertherat, Márta Medvecz, Attila Patócs
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Carney complex (CNC) is an ultrarare disorder causing cutaneous and cardiac myxomas, primary pigmented nodular adrenocortical disease, hypophyseal adenoma, and gonadal tumours. Genetic alterations are often missed under routine genetic testi
Externí odkaz:
https://doaj.org/article/31ca46c6b9444be99130d24177c8af51
Autor:
Vince Kornél Grolmusz, Petra Nagy, István Likó, Henriett Butz, Tímea Pócza, Anikó Bozsik, János Papp, Edit Oláh, Attila Patócs
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is a common genetic predisposition to cancer due to germline mutations in genes affecting DNA mismatch repair. Due to mismatch repair deficiency, developing
Externí odkaz:
https://doaj.org/article/eeb7b1b4eb274540b976ba88a6389a57
Autor:
Sára Pálla, Judit Tőke, Anikó Bozsik, Henriett Butz, János Papp, István Likó, Enikő Kuroli, András Bánvölgyi, Mátyás Hamar, Jerome Bertherat, Márta Medvecz, Attila Patócs
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/508602b211924a00a6c096033eb0fd58
Autor:
Henriett Butz, Éva Saskői, Lilla Krokker, Viktória Vereczki, Alán Alpár, István Likó, Erika Tóth, Erika Szőcs, Mihály Cserepes, Katalin Nagy, Imre Kacskovics, Attila Patócs
Publikováno v:
Cells, Vol 12, Iss 5, p 784 (2023)
Background. The dual role of GCs has been observed in breast cancer; however, due to many concomitant factors, GR action in cancer biology is still ambiguous. In this study, we aimed to unravel the context-dependent action of GR in breast cancer. Met
Externí odkaz:
https://doaj.org/article/f58999a2c3d24be8b480e8bb5c8bb000
Autor:
Éva Saskői, Zoltán Hujber, Gábor Nyírő, István Likó, Barbara Mátyási, Gábor Petővári, Katalin Mészáros, Attila L. Kovács, László Patthy, Shreyas Supekar, Hao Fan, Gergely Sváb, László Tretter, Arunabh Sarkar, Aamir Nazir, Anna Sebestyén, Attila Patócs, Anil Mehta, Krisztina Takács-Vellai
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 10 (2020)
The conserved B-subunit of succinate dehydrogenase (SDH) participates in the tricarboxylic acid cycle (TCA) cycle and mitochondrial electron transport. The Arg230His mutation in SDHB causes heritable pheochromocytoma/paraganglioma (PPGL). In Caenorha
Externí odkaz:
https://doaj.org/article/7c1d0304ba7343859b97c8211ee13c19
Autor:
Ágnes Molnár, Attila Patócs, István Likó, Gábor Nyírő, Károly Rácz, Miklós Tóth, Beatrix Sármán
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-6 (2018)
Abstract Background Glucocorticoid resistance is a rare, sporadic or familial condition caused by mutation of the gene encoding the glucocorticoid receptor (GR). Clinically it is characterized by symptoms developed due to local, tissue-specific, or g
Externí odkaz:
https://doaj.org/article/f14a47aba6e6400fa807b860d9caefd7
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11778 (2021)
Glucocorticoids (GCs) are pleiotropic hormones which regulate innumerable physiological processes. Their comprehensive effects are due to the diversity of signaling mechanism networks. MiRNAs, small, non-coding RNAs contribute to the fine tuning of s
Externí odkaz:
https://doaj.org/article/99318f6957b949ba87b9f77b5488d4a6
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Coincidences of more than one pathogenic mutation in high and/or moderate risk-associated cancer genes have been rarely reported, and the implication for disease progression has been debated. We present a case harboring two autosomal dominant inherit
Externí odkaz:
https://doaj.org/article/b96fd2954f684c6283a173089810383c
Autor:
Dóra Tombácz, Zsolt Csabai, Péter Oláh, Zsolt Balázs, István Likó, Laura Zsigmond, Donald Sharon, Michael Snyder, Zsolt Boldogkői
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162868 (2016)
Whole transcriptome studies have become essential for understanding the complexity of genetic regulation. However, the conventionally applied short-read sequencing platforms cannot be used to reliably distinguish between many transcript isoforms. The
Externí odkaz:
https://doaj.org/article/31c897fb9f584a6c84f34fb2c8e8e4df