Zobrazeno 1 - 10
of 35
pro vyhledávání: '"István András Szijártó"'
Autor:
Mario Kaßmann, István András Szijártó, Concha F. García‐Prieto, Gang Fan, Johanna Schleifenbaum, Yoland‐Marie Anistan, Christoph Tabeling, Yu Shi, Ferdinand le Noble, Martin Witzenrath, Yu Huang, Lajos Markó, Mark T. Nelson, Maik Gollasch
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 9 (2019)
Background Hypertension is the major risk factor for cardiovascular disease, the most common cause of death worldwide. Resistance arteries are capable of adapting their diameter independently in response to pressure and flow‐associated shear stress
Externí odkaz:
https://doaj.org/article/a9b9c6e3995a44efbfea4301b0b60f40
Autor:
Luiza A Rabelo, Mihail Todiras, Valéria Nunes-Souza, Fatimunnisa Qadri, István András Szijártó, Maik Gollasch, Josef M Penninger, Michael Bader, Robson A Santos, Natalia Alenina
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0150255 (2016)
Accumulating evidence indicates that angiotensin-converting enzyme 2 (ACE2) plays a critical role in cardiovascular homeostasis, and its altered expression is associated with major cardiac and vascular disorders. The aim of this study was to evaluate
Externí odkaz:
https://doaj.org/article/8a5a6456838c46fdb0a4f58f516c7a02
Autor:
Alla B. Salmina, Yulia K. Komleva, István András Szijártó, Yana V. Gorina, Olga eLopatina, Galina E. Gertsog, Milos R. Filipovic, Maik eGollasch
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Alzheimer’s type of neurodegeneration dramatically affects H2S and NO synthesis and interactions in the brain, which results in deregulated vasomotor function, brain tissue hypoperfusion and hypoxia, development of perivascular inflammation, promot
Externí odkaz:
https://doaj.org/article/2d4adea12c4d478f8a23f7d7bfae28a0
Autor:
Eszter Sélley, Gergő A. Molnár, Szilárd Kun, István András Szijártó, Boglárka Laczy, Tibor Kovács, Ferenc Fülöp, István Wittmann
Publikováno v:
Artery Research, Vol 11 (2015)
Background: Incretine hormone glucagon-like peptide-1 (GLP-1) causes dose-dependent relaxation of the thoracic aorta of rats and other arteries via nitric oxide (NO), cAMP and ATP-sensitive potassium channels, however, through a mechanism not thoroug
Externí odkaz:
https://doaj.org/article/cf9a4c336674405097da15e549e504b0
Autor:
Carolin Köhn, Johanna Schleifenbaum, István András Szijártó, Lajos Markó, Galyna Dubrovska, Yu Huang, Maik Gollasch
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41951 (2012)
BACKGROUND: Hydrogen sulfide (H(2)S) is a potent vasodilator. However, the complex mechanisms of vasoregulation by H(2)S are not fully understood. We tested the hypotheses that (1) H(2)S exerts vasodilatory effects by opening KCNQ-type voltage-depend
Externí odkaz:
https://doaj.org/article/bfdf2eb03a97442f82739c4432f8b09f
Autor:
Szilárd Kun, Melinda Kertész, Gergő A. Molnár, István András Szijártó, István Wittmann, Eszter Sélley
Publikováno v:
Hormone and Metabolic Research. 48:476-483
Glucagon is known for its insulin-antagonist effect in the blood glucose homeostasis, while it also reduces vascular resistance. The mechanism of the vasoactive effect of glucagon has not been studied before; thereby we aimed to investigate the media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b965b0cc03a10636132bbcab664ac16a
https://doi.org/10.1055/s-0042-101794
https://doi.org/10.1055/s-0042-101794
Autor:
Luiza A. Rabelo, Noriyuki Akahoshi, Maik Gollasch, Martin Witzenrath, Jens Tank, Milos R. Filipovic, Ning Wang, Christoph Tabeling, Dmitry Tsvetkov, Jan Lj. Miljkovic, Isao Ishii, István András Szijártó, Lajos Markó, Shotaro Kamata, André Diedrich
Hydrogen sulfide (H 2 S) and NO are important gasotransmitters, but how endogenous H 2 S affects the circulatory system has remained incompletely understood. Here, we show that CTH or CSE (cystathionine γ-lyase)-produced H 2 S scavenges vascular NO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cae6b3a21d8fe331dbb5eaaf40704c
https://elib.dlr.de/125385/
https://elib.dlr.de/125385/
Autor:
Johannes-Peter Stasch, Hendrik Bartolomaeus, Lajos Markó, Nicola Wilck, Ralf Dechend, Damian Brockschnieder, Axel Kretschmer, Nadine Haase, Peter Sandner, Nadine Reichhart, Olaf Strauss, István András Szijártó, Florian Sohler, Florian Herse, Arnd Heuser, András Balogh, Ralf Lesche, Friedrich C. Luft, Dominik N. Müller, Maik Gollasch, Kristin Kräker
Publikováno v:
JCI Insight, Vol 3, Iss 4 (2018)
Heart failure with preserved ejection fraction (HFpEF) can arise from cardiac and vascular remodeling processes following long-lasting hypertension. Efficacy of common HF therapeutics is unsatisfactory in HFpEF. Evidence suggests that stimulators of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7a19f68bb9a9d716a1923be24a1ec7
https://doi.org/10.1172/jci.insight.96006
https://doi.org/10.1172/jci.insight.96006
Autor:
Boglárka Laczy, Gergő A. Molnár, István András Szijártó, István Wittmann, Katalin Böddi, Esztella Mikolás, Judit Cseh, Anikó Takátsy, A. Koller, Tibor Kovács, Viktória Fisi, Maik Gollasch
Publikováno v:
Hormone and Metabolic Research. 46:749-752
studies have shown that in diabetes mellitus, insulin-induced relaxation of arteries is impaired and the level of ortho -tyrosine ( o -Tyr), an oxidized amino acid is increased. Thus, we hypothesized that elevated vascular level of o -Tyr contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3434f230d7166fef0ce10f46b3a881
https://doi.org/10.1055/s-0034-1387701
https://doi.org/10.1055/s-0034-1387701
Autor:
Stefanie Weinert, Yoland-Marie Anistan, István András Szijártó, Thomas J. Jentsch, Natalia Alenina, Jean-Yves Tano, Michael Bader, Asif R. Pathan, Nancy J. Rusch, Hantz C. Hercule, Mario Kassmann, Johanna Schleifenbaum, Maik Gollasch, Matthias Heidenreich
Publikováno v:
Circulation Research. 115:263-272
Rationale : Vascular wall stretch is the major stimulus for the myogenic response of small arteries to pressure. The molecular mechanisms are elusive, but recent findings suggest that G protein–coupled receptors can elicit a stretch response. Objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f20768585f2bf941883d2ad683cf200
https://doi.org/10.1161/circresaha.115.302882
https://doi.org/10.1161/circresaha.115.302882