Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Issam AlDiri"'
Autor:
Kamakshi Mehta, Marwa Daghsni, Reza Raeisossadati, Zhongli Xu, Emily Davis, Abigail Naidich, Bingjie Wang, Shiyue Tao, Shaohua Pi, Wei Chen, Dennis Kostka, Silvia Liu, Jeffrey M. Gross, Takaaki Kuwajima, Issam Aldiri
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114291- (2024)
Summary: Atoh7 is transiently expressed in retinal progenitor cells (RPCs) and is required for retinal ganglion cell (RGC) differentiation. In humans, a deletion in a distal non-coding regulatory region upstream of ATOH7 is associated with optic nerv
Externí odkaz:
https://doaj.org/article/591410730ffa4292b18f0c57c4a40aa5
Autor:
Reza Raeisossadati, Merari F. R. Ferrari, Alexandre Hiroaki Kihara, Issam AlDiri, Jeffrey M. Gross
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)
Abstract In the developing vertebrate retina, retinal progenitor cells (RPCs) proliferate and give rise to terminally differentiated neurons with exquisite spatio-temporal precision. Lineage commitment, fate determination and terminal differentiation
Externí odkaz:
https://doaj.org/article/d3b1333db19d4d2b815fbbf7eb746272
Autor:
Marwa Daghsni, Issam Aldiri
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Regulation of gene expression by chromatin structure has been under intensive investigation, establishing nuclear organization and genome architecture as a potent and effective means of regulating developmental processes. The substantial growth in ou
Externí odkaz:
https://doaj.org/article/89c03254e4674d5d920c3d2029d07a95
Autor:
Lu Wang, Daniel Hiler, Beisi Xu, Issam AlDiri, Xiang Chen, Xin Zhou, Lyra Griffiths, Marc Valentine, Abbas Shirinifard, András Sablauer, Suresh Thiagarajan, Marie-Elizabeth Barabas, Jiakun Zhang, Dianna Johnson, Sharon Frase, Michael A. Dyer
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2601-2614 (2018)
Summary: Diverse cell types can be reprogrammed into pluripotent stem cells by ectopic expression of Oct4 (Pou5f1), Klf4, Sox3, and Myc. Many of these induced pluripotent stem cells (iPSCs) retain memory, in terms of DNA methylation and histone modif
Externí odkaz:
https://doaj.org/article/32826e1ff45b444b95904cbff6ba595c
Publikováno v:
Development
Vsx2 is a transcription factor essential for retinal proliferation and bipolar cell differentiation, but the molecular mechanisms underlying its developmental roles are unclear. Here, we have profiled VSX2 genomic occupancy during mouse retinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cfd00a756be8ffbdfec1d2c23b51e9
https://europepmc.org/articles/PMC9440754/
https://europepmc.org/articles/PMC9440754/
Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma
Autor:
Michael A. Dyer, David Finkelstein, Dianna A. Johnson, Jiakun Zhang, Xiang Chen, Issam Aldiri, Beisi Xu, Len A. Pennacchio, Claudia A. Benavente, Itsuki Ajioka, Jennifer A. Akiyama
Publikováno v:
Development (Cambridge, England)
Retinal development requires precise temporal and spatial coordination of cell cycle exit, cell fate specification, cell migration and differentiation. When this process is disrupted, retinoblastoma, a developmental tumor of the retina, can form. Epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eb4fb54d63d456227646f5f357990d
https://doi.org/10.1242/dev.124800
https://doi.org/10.1242/dev.124800
Autor:
Jacqueline M. Roberts, Issam Aldiri, Michael R. Steele, Kathryn B. Moore, Mary A. Logan, Monica L. Vetter
Publikováno v:
Developmental biology. 437(1)
Neural basic helix-loop helix (bHLH) transcription factors promote progenitor cell differentiation by activation of downstream target genes that coordinate neuronal differentiation. Here we characterize a neural bHLH target gene in Xenopus laevis, ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cd5adda7ad2fef97c524ff625514bf
https://pubmed.ncbi.nlm.nih.gov/29518376
https://pubmed.ncbi.nlm.nih.gov/29518376
Publikováno v:
Development. 140:2867-2878
The histone methyltransferase complex PRC2 controls key steps in developmental transitions and cell fate choices; however, its roles in vertebrate eye development remain unknown. Here, we report that in Xenopus, PRC2 regulates the progression of reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63dfe964d7a97898cc2481a6c55261c0
https://doi.org/10.1242/dev.088096
https://doi.org/10.1242/dev.088096
Autor:
Issam Aldiri, Monica L. Vetter
Publikováno v:
Developmental Biology. 367(2):91-99
During organogenesis, tissues expand in size and eventually acquire consistent ratios of cells with dazzling diversity in morphology and function. During this process progenitor cells exit the cell cycle and execute differentiation programs through e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12912a3ac8751a6d9a0ac802d480bdd5
Autor:
Issam Aldiri, Monica L. Vetter
Publikováno v:
Developmental Dynamics. 238:3185-3192
The Polycomb repressive complex 2 is a multimeric aggregate that mediates silencing of a broad range of genes, and is associated with important biological contexts such as stem cell maintenance and cancer progression. PRC2 mainly trimethylates lysine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba8e17b6eef38676f5be7d961feafd7
https://doi.org/10.1002/dvdy.22120
https://doi.org/10.1002/dvdy.22120