Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Israr-ul H. Ansari"'
Autor:
Mahmoud El Azzouny, Melissa J. Longacre, Israr-ul H. Ansari, Robert T. Kennedy, Charles F. Burant, Michael J. MacDonald
Publikováno v:
Molecular Metabolism, Vol 5, Iss 10, Pp 980-987 (2016)
Objective: Glucose-stimulated insulin secretion in pancreatic beta cells requires metabolic signals including the generation of glucose-derived short chain acyl-CoAs in the cytosol from mitochondrially-derived metabolites. One concept of insulin secr
Externí odkaz:
https://doaj.org/article/6f3c5388e8594e419be8953d195d26ab
Autor:
Israr-ul H. Ansari, Rob Striker
Publikováno v:
Viruses, Vol 4, Iss 12, Pp 3303-3315 (2012)
Hepatitis C virus (HCV) is susceptible to cyclosporine (CsA) and other cyclophilin (CypA) inhibitors, but the genetic basis of susceptibility is controversial. Whether genetic variation in NS5A alters cell culture susceptibility of HCV to CypA inhibi
Externí odkaz:
https://doaj.org/article/9df2c945203d4f5593d2a9f56503b0d7
Autor:
Michael J. MacDonald, Israr-ul H. Ansari, Amy S. Riedemann, Scott W. Stoker, Jens C. Eickhoff, Peter J. Chlebeck, Luis A. Fernandez, Melissa J. Longacre
Publikováno v:
Diabetes. 71(9)
Net synthesis of pancreatic beta cells peaks before two years of life. Beta cell mass is set within the first five years of life. Inframe translational readthrough of the NRP1 gene exon 9 into intron 9 generates a truncated neuropilin-1 protein lacki
Mitochondrial glycerol phosphate dehydrogenase (mGPD) is the rate-limiting enzyme of the glycerol phosphate redox shuttle. It was recently claimed that metformin, a first line drug used for the treatment of type 2 diabetes, inhibits liver mGPD 30-50%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621356ddd228268792ce65d7dd5b71da
https://doi.org/10.2337/figshare.14394359.v1
https://doi.org/10.2337/figshare.14394359.v1
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9815 (2010)
Hepatitis C Virus (HCV) infection is a leading indication for liver transplantation. HCV infection reoccurs almost universally post transplant, decreasing both graft longevity and patient survival. The immunosuppressant, cyclosporine A (CsA) has pote
Externí odkaz:
https://doaj.org/article/deab615814074b43a027b790af104905