The role of the essential GTPase ObgE in regulating lipopolysaccharide synthesis in Escherichia coli

Autor: Liselot Dewachter, Babette Deckers, Israel Mares-Mejía, Elen Louwagie, Silke Vercauteren, Paul Matthay, Simon Brückner, Anna-Maria Möller, Franz Narberhaus, Sibylle C. Vonesch, Wim Versées, Jan Michiels

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Abstract During growth, cells need to synthesize and expand their envelope, a process that requires careful regulation. Here, we show that the GTPase ObgE of E. coli contributes to the regulation of lipopolysaccharide (LPS) synthesis, an essential co

Externí odkaz: https://doaj.org/article/0091ee21e8a8436f8b742a845ac3a937

Molecular Basis of Plant Profilins’ Cross-Reactivity

Autor: María G. Terán, Benjamín García-Ramírez, Israel Mares-Mejía, Enrique Ortega, Andrea O’Malley, Maksymilian Chruszcz, Adela Rodríguez-Romero

Publikováno v: Biomolecules, Vol 13, Iss 4, p 608 (2023)

Profilins are ubiquitous allergens with conserved structural elements. Exposure to profilins from different sources leads to IgE-cross-reactivity and the pollen–latex–food syndrome. Monoclonal antibodies (mAbs) that cross-react with plant profili

Externí odkaz: https://doaj.org/article/8efc314d619c4e899e9cb64ec08f3a21

Publisher Correction: Structural insights into chaperone addiction of toxin-antitoxin systems

Autor: Valérie Guillet, Patricia Bordes, Cécile Bon, Julien Marcoux, Virginie Gervais, Ambre Julie Sala, Suzana Dos Reis, Nawel Slama, Israel Mares-Mejía, Anne-Marie Cirinesi, Laurent Maveyraud, Pierre Genevaux, Lionel Mourey

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)

The original version of this Article contained errors in Figures 1 and 4. In Fig. 1b, the Mtb-SecBTA sequence was displayed incorrectly. In the inset panel within Fig. 4c, the y-axis of the graph incorrectly read (Q.Rg)2 × I(Q)//(0), and should have

Externí odkaz: https://doaj.org/article/86663963fbab4cdd99bfffa04d5c24c2

Structural insights into chaperone addiction of toxin-antitoxin systems

Autor: Pierre Genevaux, Laurent Maveyraud, Suzana Dos Reis, Anne-Marie Cirinesi, Ambre Sala, Valérie Guillet, Virginie Gervais, Israel Mares-Mejía, Patricia Bordes, Nawel Slama, Lionel Mourey, Julien Marcoux, Cécile Bon

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-08747-4⟩
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
'Nature Communications ', vol: 10, pages: 782-1-1-782-15 (2019)

SecB chaperones assist protein export by binding both unfolded proteins and the SecA motor. Certain SecB homologs can also control toxin-antitoxin (TA) systems known to modulate bacterial growth in response to stress. In such TA-chaperone (TAC) syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ffc20d2cb092a770b9d121eaed91f7
https://hal.archives-ouvertes.fr/hal-02346695

Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms

Autor: Samuel Lara-González, Enrique Ortega, Israel Mares-Mejía, Siseth Martínez-Caballero, Adela Rodríguez-Romero, Patricia Cano-Sánchez, Alfredo Torres-Larios, Claudia Garay-Canales

Publikováno v: Scientific Reports

Oligomerization of allergens plays an important role in IgE-mediated reactions, as effective crosslinking of IgE- FcεRI complexes on the cell membrane is dependent on the number of exposed B-cell epitopes in a single allergen molecule or on the occu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d1ec1b1ef6cf01da16b32b26944346
https://doi.org/10.1038/srep32552