Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Israel F. Charo"'
Autor:
Jill Ford, Angela Hughson, Kihong Lim, Susana V. Bardina, Wuyuan Lu, Israel F. Charo, Jean K. Lim, Deborah J. Fowell
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The chemokine CCL7 (MCP3) is known to promote the recruitment of many innate immune cell types including monocytes and neutrophils to sites of bacterial and viral infection and eosinophils and basophils to sites of allergic inflammation. CCL7 upregul
Externí odkaz:
https://doaj.org/article/4a19ab8d9dc9495a98fb91b1e274de4c
Autor:
Florian Sennlaub, Constance Auvynet, Bertrand Calippe, Sophie Lavalette, Lucie Poupel, Shulong J. Hu, Elisa Dominguez, Serge Camelo, Olivier Levy, Elodie Guyon, Noah Saederup, Israel F. Charo, Nico Van Rooijen, Emeline Nandrot, Jean‐Louis Bourges, Francine Behar‐Cohen, José‐Alain Sahel, Xavier Guillonneau, William Raoul, Christophe Combadiere
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 11, Pp 1775-1793 (2013)
Abstract Atrophic age‐related macular degeneration (AMD) is associated with the subretinal accumulation of mononuclear phagocytes (MPs). Their role in promoting or inhibiting retinal degeneration is unknown. We here show that atrophic AMD is associ
Externí odkaz:
https://doaj.org/article/2ff2d9d1430a4fa785a7b34aa7d9d130
Autor:
Albert Zlotnik, Osamu Yoshie, Mohib Uddin, Marcus Thelen, Alexander H. Sparre-Ulrich, Silvano Sozzani, Antal Rot, Mette M. Rosenkilde, Amanda E. I. Proudfoot, Christine A. Power, Joost J. Oppenheim, Hisayuki Nomiyama, Robert J. B. Nibbs, Philip M. Murphy, Georgios L. Moschovakis, Amy E. Monaghan, Kouji Matsushima, Alberto Mantovani, Andrew D. Luster, Massimo Locati, Richard Horuk, Rebecca Hills, Gerard J. Graham, Joshua M. Farber, Reinhold Förster, Christophe Combadiere, Israel F. Charo, Amanda M. Burkhardt, Adit Ben-Baruch, Francoise Bachelerie
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Chemokine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Chemokine Receptors [438, 437, 32]) comprise a large subfamily of 7TM proteins that bind one or more chemokines, a large family of small cytokines typically possessing chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdabff92dd3a87ec119470747102cddc
https://doi.org/10.2218/gtopdb/f14/2023.1
https://doi.org/10.2218/gtopdb/f14/2023.1
Autor:
Zhenhua Miao, Linda S Ertl, Dale Newland, Bin Zhao, Yu Wang, Xiaoping Zang, James J Campbell, Xiaoli Liu, Ton Dang, Shichang Miao, Antoni Krasinski, Sreenivas Punna, Yibin Zeng, Jeffrey McMahon, Penglie Zhang, Israel F Charo, Thomas J Schall, Rajinder Singh
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192405 (2018)
Focal segmental glomerulosclerosis (FSGS) comprises a group of uncommon disorders that present with marked proteinuria, nephrotic syndrome, progressive renal failure and characteristic glomerular lesions on histopathology. The current standard of car
Externí odkaz:
https://doaj.org/article/cf8cc01cc19547ce817ea274d0923554
Autor:
Noah Saederup, Astrid E Cardona, Kelsey Croft, Makiko Mizutani, Anne C Cotleur, Chia-Lin Tsou, Richard M Ransohoff, Israel F Charo
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176931 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0013693.].
Externí odkaz:
https://doaj.org/article/9f838fc6f71247af8525f2a988b1ce8e
Autor:
Thomas J. Schall, Joseph Flores-Toro, Rakesh K. Jain, Matthew R. Sarkisian, James Campbell, Jeffrey K. Harrison, Meenal Datta, Adithya Gopinath, Rajinder Singh, Israel F. Charo, Duane Mitchell, Defang Luo
Publikováno v:
Proc Natl Acad Sci U S A
Immunotherapy directed at the PD-L1/PD-1 axis has produced treatment advances in various human cancers. Unfortunately, progress has not extended to glioblastoma (GBM), with phase III clinical trials assessing anti-PD-1 monotherapy failing to show eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997bdf6e35a00f3a51d05f087f953dd5
https://doi.org/10.1073/pnas.1910856117
https://doi.org/10.1073/pnas.1910856117
Autor:
Ton Dang, Israel F. Charo, Dale Newland, Alice Kumamoto, Vicky Chhina, Thomas J. Schall, Mali Venkat Reddy, Mcmahon Jeffrey P, Karen Ebsworth, Rajinder Singh, Simon Yau, James Campbell, Yu Wang, Shirley Liu, Penglie Zhang, Linda S. Ertl
Publikováno v:
The Journal of Immunology. 202:1687-1692
Several types of psoriasiform dermatitis are associated with increased IL-36 cytokine activity in the skin. A rare, but severe, psoriasis-like disorder, generalized pustular psoriasis (GPP), is linked to loss-of-function mutations in the gene encodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fc8e8568dfd83bfa9d5c4da9e4cd44
https://doi.org/10.4049/jimmunol.1801519
https://doi.org/10.4049/jimmunol.1801519
Autor:
Joost J. Oppenheim, Robert J. B. Nibbs, Joshua M. Farber, Amanda E. I. Proudfoot, Kouji Matsushima, Alberto Mantovani, Andrew D. Luster, Hisayuki Nomiyama, Osamu Yoshie, Christophe Combadière, Israel F. Charo, Rebecca Hills, Marcus Thelen, Mette M. Rosenkilde, Françoise Bachelerie, Massimo Locati, Antal Rot, Richard Horuk, Amanda M. Burkhardt, Reinhold Förster, Christine A. Power, Mohib Uddin, Alexander Hovard Sparre-Ulrich, Amy E. Monaghan, Philip M. Murphy, Adit Ben-Baruch, Silvano Sozzani, Georgios Leandros Moschovakis, Albert Zlotnik, Gerard J. Graham
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2020
Chemokine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Chemokine Receptors [431, 430, 32]) comprise a large subfamily of 7TM proteins that bind one or more chemokines, a large family of small cytokines typically possessing chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b69e8a453522b798c37fc1b54fd1ed5
https://doi.org/10.2218/gtopdb/f14/2020.5
https://doi.org/10.2218/gtopdb/f14/2020.5
Autor:
Zhenhua Miao, James Campbell, Rajinder Singh, Yu Wang, Yibin Zeng, Mcmahon Jeffrey P, Xiaoli Liu, Thomas J. Schall, Shichang Miao, Israel F. Charo, Bin Zhao, Linda S. Ertl, Christopher I. Li, Penglie Zhang, Ton Dang, Dale Newland
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims Diabetic nephropathy (DN) is a syndrome characterized by pathological levels of proteinuria, glomerular lesions and reduction in the glomerular filtration rate (GFR) in diabetic patients. Several lines of evidence support a role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f79ff72e60307b04feb62680c497d01
https://doi.org/10.1093/ndt/gfaa142.p0973
https://doi.org/10.1093/ndt/gfaa142.p0973
Autor:
Thomas J. Schall, Bin Zhao, James Campbell, Yu Wang, Zhenhua Miao, Israel F. Charo, Christopher I. Li, Linda S. Ertl, Rajinder Singh
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims We have recently demonstrated that small molecule inhibitors of CCR2 rapidly reduced proteinuria and preserved renal structure in animal models of diabetic nephropathy (DN) and focal segmental glomerular sclerosis (FSGS). Similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f367231e8fab790be6d14e09e277ea5e
https://doi.org/10.1093/ndt/gfaa144.p0336
https://doi.org/10.1093/ndt/gfaa144.p0336