Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Israel Coats"'
Autor:
Pamela Aubert, Mayte Suárez-Fariñas, Hiroshi Mitsui, Leanne M Johnson-Huang, Jamie Lynn Harden, Katherine C Pierson, Joseph G Dolan, Inna Novitskaya, Israel Coats, Jacob Estes, Edward W Cowen, Nicole Plass, Chyi-Chia Richard Lee, Hong-Wei Sun, Michelle A Lowes, Raphaela Goldbach-Mansky
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49408 (2012)
The autoinflammatory disorder, Neonatal-onset Multisystem Inflammatory Disease (NOMID) is the most severe phenotype of disorders caused by mutations in CIAS1 that result in increased production and secretion of active IL-1β. NOMID patients present w
Externí odkaz:
https://doaj.org/article/8a9aeb4526b5468588188cde3238cfac
Autor:
Sandra Garcet, Israel Coats, John W. Frew, Emma Guttman-Yassky, Kristina Navrazhina, Xiuzhong Zheng, James G. Krueger
Publikováno v:
J Am Acad Dermatol
Background Although hidradenitis suppurativa (HS) shares some transcriptomic and cellular infiltrate features with psoriasis, their skin proteome remains unknown. Objective To define and compare inflammatory protein biomarkers of HS and psoriasis ski
Autor:
Steven R. Cohen, Sandra Garcet, Kathleen M. Bonifacio, Judilyn Fuentes-Duculan, Mayte Suárez-Fariñas, Patrick M. Brunner, Saakshi Khattri, Riana Dutt, Xuan Li, Margeaux Oliva, Israel Coats, Norma Kunjravia, James G. Krueger, Robert Finney, Xiuzhong Zheng, Patricia Gilleaudeau, Inna Cueto, Emma Guttman-Yassky, Mary Sullivan-Whalen
Publikováno v:
Experimental Dermatology. 26:28-35
Atopic dermatitis (AD) is the most common inflammatory skin disease, but treatment options for moderate-to-severe disease are limited. Ustekinumab is an IL-12/IL-23p40 antagonist that suppresses Th1, Th17 and Th22 activation, commonly used for psoria
Autor:
Patrick M. Brunner, Mayte Suárez-Fariñas, Riana Dutt, Patricia Gilleaudeau, Emma Guttman-Yassky, Margeaux Oliva, Sandra Garcet, Xuan Li, Israel Coats, Judilyn Fuentes-Duculan, Xiuzhong Zheng, Norma Kunjravia, James G. Krueger, Inna Cueto, Mary Sullivan-Whalen, Robert Finney, Kathleen M. Bonifacio, Saakshi Khattri
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:169-178
Topical glucocorticosteroids are considered an efficient treatment option for atopic dermatitis (AD), but a global assessment of glucocorticosteroid responses on key disease circuits upon weeks to months of treatment is currently lacking.We sought to
Autor:
Mary Sullivan-Whalen, Giselle Singer, Xuan Li, Patrick M. Brunner, Ana B. Pavel, Alexandra Leonard, Danielle Baum, James G. Krueger, Shelbi Jim On, Israel Coats, Juana Gonzalez, Avidan U. Neumann, Yeriel Estrada, Judilyn Fuentes-Duculan, Sharon Rose, Sandra Garcet, Anjali S. Vekaria, Huei-Chi Wen, Xiuzhong Zheng, Kunal Malik, Mark Lebwohl, Saakshi Khattri, Emma Guttman-Yassky, Inna Cueto, Patricia Gilleaudeau, Claudia Traidl-Hoffmann
Publikováno v:
The Journal of allergy and clinical immunology. 143(1)
Background IL-22 is potentially a pathogenic cytokine in patients with atopic dermatitis (AD), but the molecular effects of IL-22 antagonism have not been defined in human subjects. Objective We sought to evaluate the cellular and molecular effects o
Autor:
James G. Krueger, Sandra Garcet, Israel Coats, Patrick M. Brunner, Emma Guttman-Yassky, Saakshi Khattri, Christopher M. Tipton, Ryan O. Emerson
Publikováno v:
Allergy. 72(12)
Background Atopic dermatitis (AD) is characterized by robust immune activation. Various T-cell subsets, including Th2/Th22 cells, are increased in lesional and non-lesional skin. However, there is conflicting literature on the diversity of the T-cell
Autor:
Diane Felsen, Nicholas Gulati, John A. Carucci, Maria Vittoria Cannizzaro, Mayte Suárez-Fariñas, Israel Coats, James G. Krueger, Hiroshi Mitsui, Kejal R. Shah
Publikováno v:
The Journal of investigative dermatology
The precise mechanisms governing invasion at the leading edge of squamous cell carcinoma (SCC) and its subsequent metastasis are not fully understood. We aimed to define the cancer-related molecular changes that distinguish noninvasive tumor from inv
Publikováno v:
SPIE Proceedings.
The optical properties of pigmented lesions have been studied using diffuse reflectance spectroscopy in a noninvasive configuration on optically thick samples such as skin in vivo. However, it is difficult to un-mix the effects of absorption and scat
Autor:
Juana Gonzalez, John A. Carucci, James G. Krueger, Mayte Suárez-Fariñas, Israel Coats, Kejal R. Shah, Hiroshi Mitsui, Diane Felsen, Claire Q.F. Wang, Hanna Ning, Jie Chen
Publikováno v:
Oncotarget
// Hanna Ning 1,* , Hiroshi Mitsui 1,* , Claire Q.F. Wang 1 , Mayte Suarez-Farinas 1,2 , Juana Gonzalez 1,2 , Kejal R. Shah 3 , Jie Chen 4 , Israel Coats 1 , Diane Felsen 4 , John A. Carucci 5 , and James G. Krueger 1 1 Laboratory for Investigative D
Autor:
Claire Q.F. Wang, Diane Felsen, Shali Zhang, Juana Gonzalez, John A. Carucci, Hiroshi Mitsui, Mayte Suárez-Fariñas, Kejal R. Shah, Daniel A. Belkin, Israel Coats, James G. Krueger
Publikováno v:
JAMA dermatology. 149(2)
To characterize the presence of CD200 and CD200 receptor (CD200R) in the human cutaneous squamous cell carcinoma (SCC) microenvironment and to define a possible role for the CD200 axis in immune evasion by SCC.Gene expression in SCC vs normal skin wa