Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Israa H. Isawi"'
Autor:
Ahmed H. Al Sharie, Yazan O. Al Zu’bi, Tamam El-Elimat, Kinda Al-Kammash, Alma Abu Lil, Israa H. Isawi, Sarah Al Sharie, Balqis M. Abu Mousa, Abubaker A. Al Malkawi, Feras Q. Alali
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 2, p 295 (2023)
Background: Over the past decade, transcriptome profiling has elucidated many pivotal pathways involved in oncogenesis. However, a detailed comprehensive map of tumorigenesis remains an enigma to solve. Propelled research has been devoted to investig
Externí odkaz:
https://doaj.org/article/f89812f1d66b497e8d4d21ef3fdd8d4d
Autor:
Israa H. Isawi, Paula Morales, Noori Sotudeh, Dow P. Hurst, Diane L. Lynch, Patricia H. Reggio
Publikováno v:
Molecules, Vol 25, Iss 3, p 725 (2020)
GPR6 is an orphan G protein-coupled receptor that has been associated with the cannabinoid family because of its recognition of a sub-set of cannabinoid ligands. The high abundance of GPR6 in the central nervous system, along with high constitutive a
Externí odkaz:
https://doaj.org/article/b29654b473574beeb8a32aa15d7b44d4
Autor:
Sonja L. Knowles, Antonis Rokas, Cedric J. Pearce, Laura Flores-Bocanegra, Nicholas H. Oberlies, Huzefa A. Raja, Patricia H. Reggio, Joanna E. Burdette, Israa H. Isawi
Publikováno v:
Organic Letters. 22:1878-1882
Wheldone (1) was isolated and elucidated from a coculture of Aspergillus fischeri (NRRL 181) and Xylaria flabelliformis (G536), where secondary metabolite biosynthesis was stimulated by antagonism between these fungi. First observed via in situ analy
Chapter 5. Natural and Synthetic Cannabinoids Targeting Non-CB1, Non-CB2 G Protein-coupled Receptors
Cannabinoids have emerged in the last decades as promising therapeutic tools for the treatment of a wide range of neurological, metabolic or oncologic diseases, among others. These molecules mainly target the so-called CB1 and CB2 cannabinoid recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ddd176a8d8fed4385fb3d992ce9ad68
https://doi.org/10.1039/9781839160752-00168
https://doi.org/10.1039/9781839160752-00168
Publikováno v:
Drug Metabolism Reviews. 50:74-93
GPR3, GPR6, and GPR12 are three orphan receptors that belong to the Class A family of G-protein-coupled receptors (GPCRs). These GPCRs share over 60% of sequence similarity among them. Because of their close phylogenetic relationship, GPR3, GPR6, and
Publikováno v:
Proceedings, Vol 22, Iss 1, p 29 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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© 2019 by the authors.
The orphan G protein coupled receptor 6 (GPR6) is a cannabinoid-related Class A GPCR. It is highly expressed in the central nervous system and exhibits high constitutive activation of adenylyl cyclase. Several research gr
The orphan G protein coupled receptor 6 (GPR6) is a cannabinoid-related Class A GPCR. It is highly expressed in the central nervous system and exhibits high constitutive activation of adenylyl cyclase. Several research gr
Autor:
Israa H. Isawi, Nizar M. Mhaidat, Qosay Al-Balas, Nizar A. Al-Shar’i, Mohammad A. Hassan, Fatima M Al-Mahasneh, Ammar Almaaytah
Publikováno v:
Drug Design, Development and Therapy. 10:2623-2629
Qosay A Al-Balas,1 Mohammad A Hassan,1 Nizar A Al-Shar’i,1 Nizar M Mhaidat,2 Ammar M Almaaytah,3 Fatima M Al-Mahasneh,1 Israa H Isawi1 1Department of Medicinal Chemistry and Pharmacognosy, 2Department of Clinical Pharmacy, 3Department of Pharmaceut
Publikováno v:
Publons
Autor:
Qosay A, Al-Balas, Mohammad A, Hassan, Nizar A, Al-Shar'i, Nizar M, Mhaidat, Ammar M, Almaaytah, Fatima M, Al-Mahasneh, Israa H, Isawi
Publikováno v:
Drug Design, Development and Therapy
Background The glyoxalase system including two thiol-dependent enzymes, glyoxalase I (Glo-I) and glyoxalase II, plays an important role in a ubiquitous metabolic pathway involved in cellular detoxification of cytotoxic 2-oxoaldehydes. Tumor cells hav