Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Isora V Sernandez"'
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3927 (2008)
The humoral immune response critically relies on the secondary diversification of antibodies. This diversification takes places through somatic remodelling of the antibody genes by two molecular mechanisms, Class Switch Recombination (CSR) and Somati
Externí odkaz:
https://doaj.org/article/5edb5dda04a4474295dba5da62a3db5c
Autor:
Pilar Delgado, Ángel F Álvarez-Prado, Ester Marina-Zárate, Isora V Sernandez, Sonia M Mur, Jorge de la Barrera, Fátima Sanchez-Cabo, Marta Cañamero, Antonio de Molina, Laura Belver, Virginia G de Yébenes, Almudena R Ramiro
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1008960 (2020)
Most B cell lymphomas originate from B cells that have germinal center (GC) experience and bear chromosome translocations and numerous point mutations. GC B cells remodel their immunoglobulin (Ig) genes by somatic hypermutation (SHM) and class switch
Externí odkaz:
https://doaj.org/article/47010793637940ca8b4438470ea1baf5
Autor:
Arantxa Pérez‐García, Pablo Pérez‐Durán, Thomas Wossning, Isora V Sernandez, Sonia M Mur, Marta Cañamero, Francisco X Real, Almudena R Ramiro
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 10, Pp 1327-1336 (2015)
Abstract Activation‐induced deaminase (AID) initiates secondary antibody diversification in germinal center B cells, giving rise to higher affinity antibodies through somatic hypermutation (SHM) or to isotype‐switched antibodies through class swi
Externí odkaz:
https://doaj.org/article/f845f41e876b414eaa2cf320fdb7f77d