Substituted tetrahydroisoquinolines: synthesis, characterization, antitumor activity and other biological properties

Autor: Jaime Rubio-Martinez, Richard Soucek, Daniel Henri Caignard, A. Sergi Capilla, Laura Grau, Maria Dolors Pujol, M. Romero

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

A novel group of aryl methyl sulfones based on nonsteroidal anti-inflammatory compounds exhibiting a methyl sulfone instead of the acetic or propionic acid group was designed, synthesized and evaluated in vitro for inhibition against the human cycloo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2d51198f10700efde0b824e8642d51
https://doi.org/10.1016/j.ejmech.2017.12.098

In vitro Antiplasmodial Activities of Alkaloids Isolated from Roots of Worsleya procera (Lem.) Traub (Amaryllidaceae)

Autor: Juan C. Tenorio, Raphael Conti, Javier Ellena, Camila Lima Zanini, Jean Paulo de Andrade, Glaucius Oliva, Anna Caroline Campos Aguiar, Rafael Victorio Carvalho Guido, Jaume Bastida, Juliana Oliveira de Souza, Karla L. Gonring-Salarini, Warley de Souza Borges, Bárbara Juliana Pinheiro Borges

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of the Brazilian Chemical Society v.30 n.8 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 30, Issue: 8, Pages: 1624-1633, Published: 12 AUG 2019

A combined phytochemical, crystallographic and biological study of Worsleya procera roots was performed. Fifteen alkaloids were identified by gas chromatography mass spectrometry (GC-MS) and seven of them were isolated. The structures of the alkaloid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62eb8dacf769f7b66f00f22bbedb8a5b
http://hdl.handle.net/2445/167237

Synthesis and X-ray diffraction data of 2-ethyl-6-(pyridin-4-yl)-7H-indeno [2,1-c]quinoline

Autor: Sánchez García, Andrés

El compuesto 2-etil-6- (piridin-4-il) -7H-indeno [2,1-c] quinolina (2) (fórmula química C23H22N2) se sintetizó a través de la reacción de oxidación del disolvente libre mediada por azufre elemental del correspondiente 2-etil-6- (piridin-4-il) -

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3896::cbc5e8b7e6ec6ad4cf7ca3740f16440b
https://hdl.handle.net/11634/18550

ENVOLVIMENTO DOS SISTEMAS SEROTONINÉRGICO E DOPAMINÉRGICO NA AÇÃO DO TIPO ANTIDEPRESSIVA DO 7-FLÚOR-1,3 DIFENILISOQUINOLINA-1-AMINO EM CAMUNDONGOS

Autor: Pesarico, Ana Paula

Publikováno v: Repositório Institucional da UFSMUniversidade Federal de Santa MariaUFSM.

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Depression is a psychiatric disorder associated with a negative impact on quality of life. Monoaminergic system has been involved in this disease and in the action of antidepressant

Externí odkaz: http://repositorio.ufsm.br/handle/1/11237

Evaluation of pharmacologyc and toxicologyc effects of 4-organochalcogen-isoquinolines

Autor: Sampaio, Tuane Bazanella

Publikováno v: Biblioteca Digital de Teses e Dissertações do UFSM
Universidade Federal de Santa Maria (UFSM)
instacron:UFSM

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Monoamine oxidase (MAO) is a target enzyme in the treatment of several pathologies, being that new molecules which inhibit of a selective, potent and reversible manner their isoforms and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::b29fe5d699c0cf7f6aa395eaa7cae956
http://repositorio.ufsm.br/handle/1/11226