Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Isonicotinamide derivative"'
Autor:
Jolanta Orzelska-Górka, Elisa Magli, Ferdinando Fiorino, Elisa Perissutti, Paola Massarelli, Cristina Nencini, Vincenzo Santagada, Ewa Kędzierska, Giuseppe Caliendo, Angelo A. Izzo, Ilaria Rossi, Anna Bielenica, Paola Di Vaio, Francesco Frecentese, Angela Corvino, Antonio Ciano, Raffaele Capasso, Beatrice Severino
Publikováno v:
European Journal of Medicinal Chemistry. 110:133-150
Isonicotinamide derivatives, linked to an arylpiperazine moiety, were prepared and their affinity to 5-HT 1A , 5-HT 2A and 5-HT 2C receptors were evaluated. The combination of structural elements (heterocyclic nucleus, alkyl chain and 4-substituted p
Autor:
Piotr Wlaź, Mariola Herbet, Ferdinando Fiorino, Angela Corvino, Ewa Kędzierska, Ewa Poleszak, Flavia Giordano, Ewa Gibula, Jarosław Dudka, Jolanta Kotlinska
Publikováno v:
Fundamentalclinical pharmacology. 33(3)
Anxiety disorder is a great challenge for modern psychopharmacology. Although a variety of single drugs are used in the treatment of anxiety, it is important to search for new therapeutics with faster onset of action, fewer side effects, and higher e
Autor:
Bartosz Knap, Jolanta Kotlinska, Ewa Kędzierska, Jolanta Orzelska-Górka, Ewa Poleszak, Elisa Magli, Piotr Wlaź, Ferdinando Fiorino
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 392(6)
Therapy of depression is difficult and still insufficient despite the presence of many antidepressants on the market. Therefore, there is a constant need to search for new, safer, and more effective drugs that could be used in the treatment of depres