Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Isolde Reimold"'
Autor:
Melanie Ott, Evelyn Hollnack-Pusch, Anne Mahringer, Valeska Reichel, Caroline MacLean, Gert Fricker, Isolde Reimold
Publikováno v:
Journal of Nanoneuroscience. 2:5-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dbf9596cce9e035a2989113a27580b4
https://doi.org/10.1166/jns.2012.1012
https://doi.org/10.1166/jns.2012.1012
Autor:
Christoph A. Seyfried, Joe Bender, Isolde Reimold, Gert Fricker, Diana Domke, Hans-Eckhard Radunz
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 70:627-632
This study aimed to explore and extend the application potential of poly( n -butylcyano-acrylate) (PBCA) nanoparticles to cross the blood–brain barrier (BBB) and to deliver their content into the central nervous system. PBCA particles were prepared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1605eb51ef1aaa89846854a38966349
https://doi.org/10.1016/j.ejpb.2008.05.007
https://doi.org/10.1016/j.ejpb.2008.05.007
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 197
Therapy of diseases of the central nervous system is a major challenge since drugs have to overcome the blood-brain barrier (BBB). A powerful strategy to enhance cerebral drug concentration is administration of drug-loaded poly(n-butylcyano-acrylate)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a7d1ff200ec81af52332f180c635d4
https://pubmed.ncbi.nlm.nih.gov/25445700
https://pubmed.ncbi.nlm.nih.gov/25445700
Autor:
Martin Brandl, Gert Fricker, Sarah Maud Fischer, Johannes Parmentier, Isolde Reimold, Stephen T. Buckley
Publikováno v:
Fischer, S, Buckley, S & Brandl, M 2012, ' Oral bioavailability of ketoprofen in suspension and solution formulations in rats: the influence of poloxamer 188 ', Journal of Pharmacy and Pharmacology, vol. 64, no. 11, pp. 1631-37 . https://doi.org/10.1111/j.2042-7158.2012.01541.x
Objectives The aim of the current study was to investigate the effect of poloxamer 188 (P-188) on the bioavailability of the BCS class 2 drug ketoprofen in vivo. Methods Aqueous suspension and solution formulations of ketoprofen with and without P-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a692cae193ee8304edb0adecc532189
https://portal.findresearcher.sdu.dk/da/publications/91a48da5-6738-485f-b153-b2bc2343890b
https://portal.findresearcher.sdu.dk/da/publications/91a48da5-6738-485f-b153-b2bc2343890b
Autor:
Martin Brandl, Sandra Martins, Gert Fricker, Ingunn Tho, Isolde Reimold, Eliana B. Souto, Domingos Ferreira
Publikováno v:
Martins, S, Tho, I, Reimold, I, Fricker, G, Souto, E, Ferreira, D & Brandl, M 2012, ' Brain delivery of camptothecin by means of solid lipid nanoparticles: Formulation design, in vitro and in vivo studies ', International Journal of Pharmaceutics, vol. 439, no. 1-2, pp. 49-62 . https://doi.org/10.1016/j.ijpharm.2012.09.054
For the purpose of brain delivery upon intravenous injection, formulations of camptothecin-loaded solid lipid nanoparticles (SLN), prepared by hot high pressure homogenisation, were designed. Incorporation of camptothecin in the hydrophobic and acidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83f8e9c614842f2b1dd19ac2d8f7226
https://portal.findresearcher.sdu.dk/da/publications/993d4764-3014-4438-8e17-a23fead0a971
https://portal.findresearcher.sdu.dk/da/publications/993d4764-3014-4438-8e17-a23fead0a971
Publikováno v:
Current pharmaceutical design. 17(26)
According to the World Health Organization Central nervous system disorders are the major medical challenge of the 21st Century, yet treatments for many CNS disorders are either inadequate or absent. One reason is the existence of the blood-brain bar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b87abc75fa01acb507e8ea25b89cb9
https://pubmed.ncbi.nlm.nih.gov/21827407
https://pubmed.ncbi.nlm.nih.gov/21827407