MASLD does not affect fertility and senolytics fail to prevent MASLD progression in male mice.

Autor: Hense JD; Nutrition College, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 Sala 228, Pelotas, RS, CEP 9601-610, Brazil., Garcia DN; Nutrition College, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 Sala 228, Pelotas, RS, CEP 9601-610, Brazil., Zanini BM; Nutrition College, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 Sala 228, Pelotas, RS, CEP 9601-610, Brazil., Barreto MM; Nutrition College, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 Sala 228, Pelotas, RS, CEP 9601-610, Brazil., Perreira GC; Nutrition College, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 Sala 228, Pelotas, RS, CEP 9601-610, Brazil., Isola JVV; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma, OK, USA., de Brito C; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma, OK, USA., Fornalik M; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma, OK, USA., Mondal SA; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma, OK, USA.; Department of Endocrinology, JIPMER, Puducherry, 605006, India., Ávila BM; Nutrition College, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 Sala 228, Pelotas, RS, CEP 9601-610, Brazil., Oliveira TL; Biotechnology Center, Universidade Federal de Pelotas, Pelotas, RS, Brazil., Rice HC; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma, OK, USA., Lacy CI; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma, OK, USA., Vaucher RA; Center for Chemical, Pharmaceutical and Food Sciences, Universidade Federal de Pelotas, Pelotas, RS, Brazil., Mason JB; Department of Veterinary Clinical and Life Sciences, Center for Integrated BioSystems, College of Veterinary Medicine, Utah State University, Logan, UT, USA., Masternak MM; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA.; Department of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland., Stout MB; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma, OK, USA.; Oklahoma City Veterans Affairs Medical Center, Oklahoma, OK, USA., Schneider A; Nutrition College, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 Sala 228, Pelotas, RS, CEP 9601-610, Brazil. augusto.schneider@ufpel.edu.br.

Publikováno v: Scientific reports [Sci Rep] 2024 Jul 27; Vol. 14 (1), pp. 17332. Date of Electronic Publication: 2024 Jul 27.

The retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity.

Autor: Wood TWP; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA., Henriques WS; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT, 59717, USA., Cullen HB; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA., Romero M; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA., Blengini CS; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA., Sarathy S; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA., Sorkin J; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA., Bekele H; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, 06511, USA., Jin C; Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY 10032, USA., Kim S; Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY 10032, USA., Chemiakine A; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA., Khondker RC; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA., Isola JVV; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Stout MB; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Gennarino VA; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.; Columbia Stem Cell Initiative, New York, NY 10032, USA.; Initiative for Columbia Ataxia and Tremor, New York, NY 10032, USA., Mogessie B; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, 06511, USA., Jain D; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA., Schindler K; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA., Suh Y; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.; Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY 10032, USA., Wiedenheft B; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT, 59717, USA., Berchowitz LE; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.; Taub Institute for Research on Alzheimer's and the Aging Brain, New York, NY, USA.

Publikováno v: Research square [Res Sq] 2024 Jul 10. Date of Electronic Publication: 2024 Jul 10.

Senolytic treatment fails to improve ovarian reserve or fertility in female mice.

Autor: Garcia DN; Faculdade de Nutrição, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 - Sala 239, Pelotas, RS, CEP 96010-610, Brazil., Hense JD; Faculdade de Nutrição, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 - Sala 239, Pelotas, RS, CEP 96010-610, Brazil., Zanini BM; Faculdade de Nutrição, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 - Sala 239, Pelotas, RS, CEP 96010-610, Brazil., Isola JVV; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Prosczek JB; Faculdade de Nutrição, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 - Sala 239, Pelotas, RS, CEP 96010-610, Brazil., Ashiqueali S; College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA., Oliveira TL; Centro de Biotecnologia, Universidade Federal de Pelotas, Pelotas, RS, Brazil., Mason JB; College of Veterinary Medicine, Department of Veterinary Clinical and Life Sciences, Center for Integrated BioSystems, Utah State University, Logan, UT, USA., Schadock IC; Experimental Toxicology Department, German Institute for Risk Assessment, Berlin, Germany., Barros CC; Faculdade de Nutrição, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 - Sala 239, Pelotas, RS, CEP 96010-610, Brazil., Stout MB; College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA., Masternak MM; College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA.; Department of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland., Schneider A; Faculdade de Nutrição, Universidade Federal de Pelotas, Rua Gomes Carneiro, 1 - Sala 239, Pelotas, RS, CEP 96010-610, Brazil. augusto.schneider@ufpel.edu.br.

Publikováno v: GeroScience [Geroscience] 2024 Jun; Vol. 46 (3), pp. 3445-3455. Date of Electronic Publication: 2024 Feb 15.

Thermoregulatory response of black or red lactating Holstein cows in the hot and cold season in southern Brazil.

Autor: Lazzari J; Veterinary Medicine Graduate Program, Federal University of Pelotas, Av. Eliseu Maciel, Capão do Leão, RS, Brazil. Electronic address: jelazzari@hotmail.com., Isola JVV; Aging & Metabolism Program, Oklahoma Medical Research Foundation, 825 NE 13th St, Oklahoma City, OK, 73104, USA. Electronic address: isolaj@omrf.org., Szambelan VL; Department of Animal Science, Federal University of Santa Maria, Av. Independência, 3751, Palmeira Das Missões, RS, Brazil. Electronic address: nessa.szambelan@gmail.com., Menegazzi G; Department of Animal Science, Faculty of Agronomy, University of the Republic, Ruta 3 Km 363, Paysandú, Uruguay. Electronic address: gmenegazzi@fagro.edu.uy., Busanello M; Department of Agricultural Sciences, High Uruguay and Missions Regional Integrated University, Av. Assis Brasil, 709, Frederico Westphalen, RS, Brazil. Electronic address: marcosbusanello@hotmail.com., Rovani MT; Department of Animal Medicine, Federal University of Rio Grande do Sul, Av. Bento Gonçalves, 9090, Agronomia, Porto Alegre, RS, Brazil. Electronic address: mtrovani@gmail.com., Sarubbi J; Department of Animal Science, Federal University of Santa Maria, Av. Independência, 3751, Palmeira Das Missões, RS, Brazil. Electronic address: jusarubbi.ufsm@hotmail.com., Schmitt E; Department of Veterinary Clinics, Federal University of Pelotas, Av. Eliseu Maciel, Capão do Leão, RS, Brazil. Electronic address: schmitt.edu@gmail.com., Ferreira R; Department of Animal Science, Santa Catarina State University, Av. Luiz de Camões, 2090, Chapecó, SC, Brazil. Electronic address: rferreirasul@gmail.com., Gonçalves PBD; Department of Physiology and Pharmacology, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address: bayard@ufsm.br., Gasperin BG; Department of Animal Pathology, Federal University of Pelotas, Av. Eliseu Maciel, Capão do Leão, RS, Brazil. Electronic address: bggasperin@gmail.com., Mondadori RG; Department of Morphology, Federal University of Pelotas, Av. Eliseu Maciel, Capão do Leão, RS, Brazil. Electronic address: rgmondadori@gmail.com.

Publikováno v: Journal of thermal biology [J Therm Biol] 2024 Apr; Vol. 121, pp. 103833. Date of Electronic Publication: 2024 Mar 21.

A single-cell atlas of the aging mouse ovary.

Autor: Isola JVV; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Ocañas SR; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Neuroscience Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Physiology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, USA., Hubbart CR; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Ko S; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Neuroscience Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Mondal SA; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Hense JD; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Nutrition College, Federal University of Pelotas, Pelotas, Brazil., Carter HNC; Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Schneider A; Nutrition College, Federal University of Pelotas, Pelotas, Brazil., Kovats S; Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Alberola-Ila J; Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Freeman WM; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, USA., Stout MB; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA. michael-stout@omrf.org.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, USA. michael-stout@omrf.org.

Publikováno v: Nature aging [Nat Aging] 2024 Jan; Vol. 4 (1), pp. 145-162. Date of Electronic Publication: 2024 Jan 10.