Reengineering the specificity of the highly selective Clostridium botulinum protease via directed evolution.

Autor: Dyer, Rebekah P.¹ (AUTHOR), Isoda, Hariny M.² (AUTHOR), Salcedo, Gabriela S.¹ (AUTHOR), Speciale, Gaetano² (AUTHOR), Fletcher, Madison H.² (AUTHOR), Le, Linh Q.³ (AUTHOR), Liu, Yi³ (AUTHOR), Brami-Cherrier, Karen³ (AUTHOR), Malik, Shiazah Z.³ (AUTHOR), Vazquez-Cintron, Edwin J.³ (AUTHOR), Chu, Andrew C.¹ (AUTHOR), Rupp, David C.³ (AUTHOR), Jacky, Birgitte P. S.³ (AUTHOR), Nguyen, Thu T. M.² (AUTHOR), Katz, Benjamin B.² (AUTHOR), Steward, Lance E.³ (AUTHOR), Majumdar, Sudipta² (AUTHOR), Brideau-Andersen, Amy D.³ (AUTHOR) amy.brideauandersen@abbvie.com, Weiss, Gregory A.^1,2,4 (AUTHOR) gweiss@uci.edu

Publikováno v: Scientific Reports. 6/15/2022, Vol. 12 Issue 1, p1-11. 11p.

Engineering SNAP23 specificity into the highly selective Clostridium botulinum protease

Autor: Dyer, Rebekah P., Isoda, Hariny M., Salcedo, Gabriela S., Speciale, Gaetano, Fletcher, Madison H., Le, Linh Q., Liu, Yi, Malik, Shiazah Z., Vazquez-Cintron, Edwin J., Chu, Andrew C., Rupp, David C., Jacky, Birgitte P.S., Nguyen, Thu T.M., Steward, Lance E., Majumdar, Sudipta, Brideau-Andersen, Amy D., Weiss, Gregory A.

Publikováno v: In Toxicon January 2021 190 Supplement 1:S19-S20