Zobrazeno 1 - 10
of 368
pro vyhledávání: '"Isocytosine"'
Akademický článek
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Autor:
Arunas Kazlauskas, Adas Darinskas, Rolandas Meškys, Arimantas Tamašauskas, Jaunius Urbonavičius
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background The cytosine deaminase (CD)/5-fluorocytosine (5-FC) system is among the best explored enzyme/prodrug systems in the field of the suicide gene therapy. Recently, by the screening of the environmental metagenomic libraries we identi
Externí odkaz:
https://doaj.org/article/5e411a3e61d745959b69442a604642c3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Cytosine is one of the four letters of a standard genetic code, found both in DNA and in RNA. This heterocyclic base can be converted into uracil upon the action of the well-known cytosine deaminase. Isocytosine (2-aminouracil) is an isomer of cytosi
Externí odkaz:
https://doaj.org/article/90208776df6a4e369aa4a38851f2bacf
Publikováno v:
ChemistrySelect. 6:2919-2922
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09690e5192ab0bfc47233c3ce0488062
https://doi.org/10.1002/slct.202100203
https://doi.org/10.1002/slct.202100203
Autor:
Dariusz Brzezinski, Mariusz Jaskolski, Marcin Kowiel, Jianbo Zhao, Miroslaw Gilski, Douglas H. Turner
Publikováno v:
Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
Revised geometrical parameters are proposed for the Watson–Crick pairs of nucleobases, for use as restraints in modeling and refinement of the structures of nucleic acids. Accurate values of these parameters were derived (and compared) from small-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94aaa0869464e9352ce23aa23195935
https://doi.org/10.1107/s2052520619002002
https://doi.org/10.1107/s2052520619002002
Publikováno v:
Croatica Chemica Acta
Volume 93
Issue 2
Volume 93
Issue 2
The imino tautomers of isocytosine were objects of investigation at the TD-DFT level of theory - TD BLYP/6-311++G(d,p). We studied the mechanisms of the H1-N detachment in these tautomers through excited-state reaction paths. It was proposed that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0a793f88bc6b9961d1d8f0f2b652e5
https://doi.org/10.5562/cca3659
https://doi.org/10.5562/cca3659
Publikováno v:
Journal of Structural Chemistry. 60:898-908
We have carried out a combined theoretical (at the TDDFT BLYP/6-311++G** level of theory) and experimental study of the mechanism of phototautmerization of the N(3)H oxo tautomer of isocytosine dissolved in a water medium. The study reveals that this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e030e271aa660be9f64d84fb04c6953
https://doi.org/10.1134/s0022476619060040
https://doi.org/10.1134/s0022476619060040
Autor:
Weronika Juras, Ewa D. Raczyńska
Publikováno v:
Computational and Theoretical Chemistry. 1148:16-26
For favored and rare prototropic tautomers of isocytosine (iC), geometric consequences of ionization, one-electron loss (iC − e → iC+ ) and one-electron gain (iC + e → iC− ), have been studied. Effects of protonation and deprotonation on geom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e18f45e47a45e60e8798897480c0618
https://doi.org/10.1016/j.comptc.2018.12.010
https://doi.org/10.1016/j.comptc.2018.12.010
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1973 Feb 01. 70(2), 512-516.
Externí odkaz:
https://www.jstor.org/stable/62532