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pro vyhledávání: '"Isobel Strang"'
Autor:
Isobel Strang, Kayhan A. Tayarani-Binazir, Mark Jairaj, Sarah Rose, Michael J. Jackson, Peter Jenner
Publikováno v:
Behavioural Pharmacology. 23:126-133
Peripheral aromatic amino acid decarboxylase (AADC) inhibitors, such as benserazide, are routinely used to potentiate the effects of L-3,4-dihydroxyphenylalanine (L-DOPA) in Parkinson's disease (PD) and in experimental models of PD. However, there is
Autor:
K. Stockwell, Bai-Yun Zeng, Maria Papathanou, Sarah Rose, Mahmoud M. Iravani, Peter Jenner, Michael J. Jackson, Andrew C. McCreary, Isobel Strang
Publikováno v:
King's College London
The treatment of dyskinesia in Parkinson׳s disease remains poor but H3 receptor agonists have been suggested as a novel pharmacological approach. We examined the effects of the H3 agonist, immepip, in 6-OHDA-lesioned rats exhibiting AIMs (abnormal i