Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Isobel D Lawrenson"'
Autor:
Stephen P. Bottomley, Robert N. Pike, Isobel D Lawrenson, Deborah J. Tew, Weiwen Dai, James C. Whisstock
Publikováno v:
Protein Science. 10:2518-2524
Serpins inhibit cognate serine proteases involved in a number of important processes including blood coagulation and inflammation. Consequently, loss of serpin function or stability results in a number of disease states. Many of the naturally occurri
Autor:
Andrew W. Boyd, Michelle Down, Paul F. Alewood, Martin Lackmann, Sabine H Wimmer-Kleikamp, Simone M. Schoenwaelder, Isobel D Lawrenson, Peter Lock
Publikováno v:
Journal of Cell Science. 115:1059-1072
Eph receptor tyrosine kinases and ephrins regulate morphogenesis in the developing embryo where they effect adhesion and motility of interacting cells. Although scarcely expressed in adult tissues, Eph receptors and ephrins are overexpressed in a ran
Autor:
Seong-Seng Tan, Jeffrey J. Babon, Tim Thomas, Danielle L. Krebs, Caitlin Collin, Nicos A. Nicola, Tamara J. McLennan, Warren S. Alexander, Andrew J. Kueh, Anne K. Voss, Jian-Guo Zhang, Isobel D. Lawrenson, Katrina S Y Koh, Helen M. McRae, Farrah El-Saafin, Tatiana B. Kolesnik, Bilal N. Sheikh, Joanne M. Britto, Edmond M. Linossi, Sandra E. Nicholson
Publikováno v:
Cerebral Cortex. :bhv253
Mutations of the reelin gene cause severe defects in cerebral cortex development and profound intellectual impairment. While many aspects of the reelin signaling pathway have been identified, the molecular and ultimate cellular consequences of reelin
Autor:
Peter G. Stockley, Isobel D. Lawrenson
Publikováno v:
FEBS Letters. (1-2):136-142
MetJ is a member of the ribbon-helix-helix class of DNA-binding proteins whose affinity for operators is apparently controlled by an unprecedented long-range electrostatic effect from the tertiary sulphur atom of its co-repressor, S-adenosyl methioni