Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Iso-cladospolide B"'
Publikováno v:
Helvetica Chimica Acta. 98:1115-1126
Total syntheses of iso-cladospolide B (1) and the 12-membered macrolactone (6S,12R)-6-hydroxy-12-methyloxacyclododecane-2,5-dione (2), a non-natural product, were achieved from a common intermediate starting from commercially available 1,9-nonane dio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ae0134b2c7df4f361b986aa6b54d6f1
https://doi.org/10.1002/hlca.201500030
https://doi.org/10.1002/hlca.201500030
Publikováno v:
Tetrahedron Letters. 54:3647-3650
A total synthesis of (4 S , 5 S , 11 R ) and (4 S , 5 S , 11 S )- iso -cladospolide B has been achieved using a commercially available starting material and our furan approach to oxacyclic systems, the proven scope of which is thus broadened.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::274d0c7b8471fc0515c4c7a83c11dd82
https://doi.org/10.1016/j.tetlet.2013.04.124
https://doi.org/10.1016/j.tetlet.2013.04.124
Publikováno v:
European Journal of Organic Chemistry. 2013:3786-3796
A general strategy for the stereoselective total syntheses of cladospolides A, B, and C and iso-cladospolide B has been accomplished. The key steps provide easy access to the target molecules and include an alkyne-zipper reaction, a Sharpless asymmet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8c58d54cef62327ef2caff71acde0a4
https://doi.org/10.1002/ejoc.201300022
https://doi.org/10.1002/ejoc.201300022
Autor:
Krishna P. Kaliappan, Debjani Si
Publikováno v:
Synlett. 23:2822-2826
A short and convergent total synthesis of (+)-cladospolide D is delineated, which involves olefin cross metathesis and furan oxidation to access the gamma-oxo-alpha,beta-unsaturated acid and Yamaguchi lactonization to construct the 12-membered ring a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02512ae9c2bbe75814a2425a715cbcfd
https://doi.org/10.1055/s-0032-1317520
https://doi.org/10.1055/s-0032-1317520
Publikováno v:
Synthesis. 44:1663-1666
Short and efficient total syntheses of (4S,5S,11R)- and (4S,5S,11S)-iso-cladospolide B were achieved in five steps each without using any protecting groups. The key steps were an alkyne-zipper reaction, a Suzuki cross coupling, and a Sharpless asymme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fdfd1aaa45f887aeff915451788f17
https://doi.org/10.1055/s-0031-1290986
https://doi.org/10.1055/s-0031-1290986
Publikováno v:
Synthesis. 2006:4041-4045
A simple and efficient stereoselective total synthesis of iso-cladospolide B and a formal total synthesis of cladospolide B, using Jacobsen's hydrolytic kinetic resolution, is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6162e369b81e6cde88821af3655b3e8
https://doi.org/10.1055/s-2006-950317
https://doi.org/10.1055/s-2006-950317
Publikováno v:
Tetrahedron Letters. 47:6531-6535
Attempts to synthesise iso-cladospolide-B, cladospolide-B and cladospolide-C resulted in macrolides 1, 2 and 4 along with butenolide 3. Of the three stereogenic centres, the C-4/C-5 vic-diol was obtained from tartaric acid and d -glucose, while the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::030fbe296e3425c02e4bbfb03171799a
https://doi.org/10.1016/j.tetlet.2006.07.043
https://doi.org/10.1016/j.tetlet.2006.07.043
Publikováno v:
Tetrahedron Letters. 47:6537-6540
The syntheses of iso-cladospolide-B, cladospolide-B and cladospolide-C are reported with 4S,5S,11S-configuration. Of the three stereogenic centres, the C-4/C-5 vic-diol was created by Evans aldol condensation, while the C-11 stereocentre was created
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0272b63e1bc73e986a7752718677932
https://doi.org/10.1016/j.tetlet.2006.07.044
https://doi.org/10.1016/j.tetlet.2006.07.044
Publikováno v:
Synlett. 2007:2891-2893
A concise total synthesis of (-)-muricatacin and (-)- ISO-cladospolide B has been achieved by using chemoselective cross-metatheses and asymmetric dihydroxylations. These key reactions allow a fast access to α-hydroxybutyrolactones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3732766e6ff35cd0f117551e4cfc214c
https://doi.org/10.1055/s-2007-990958
https://doi.org/10.1055/s-2007-990958
Publikováno v:
Tetrahedron Letters. 46:6625-6627
An efficient synthesis of iso-cladospolide B and cladospolide B has been achieved using Jacobsen’s hydrolytic kinetic resolution (HKR), Sharpless asymmetric dihydroxylation and Yamaguchi macrolactonization as the key steps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::050a787c4597c49f64481372ae2a49ec
https://doi.org/10.1016/j.tetlet.2005.07.153
https://doi.org/10.1016/j.tetlet.2005.07.153