Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ismat A Khatri"'
Publikováno v:
Leukemia Research. 69:72-80
In previous studies we had reported that the immunosuppressive cell membrane bound molecule CD200 is released from the cell following cleavage by matrix metalloproteases, with the released soluble CD200 acting as an immunosuppressant following bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fb07312407fc5bbac0100cd3de97ba
https://doi.org/10.1016/j.leukres.2018.04.007
https://doi.org/10.1016/j.leukres.2018.04.007
Publikováno v:
Leukemia Research. 68:40-47
Chronic Lymphocytic Leukemia B cells (CLL) are malignant cells which retain at least some functions of normal B cells. Paramount amongst the latter is that when such cells are appropriately stimulated, they are able to present antigens, including any
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147eed86d09cbe162892fa09bcd6160c
https://doi.org/10.1016/j.leukres.2018.03.002
https://doi.org/10.1016/j.leukres.2018.03.002
Autor:
Adrian Heini, Kai Yu, Artur J. Ulmer, Ulrich Zähringer, D Heumann, R.M. Gorczynski, Ernst Th. Rietschel, Klaus Brandenburg, Christian Alexander, Zhiqi Chen, O. Kos, Thierry Waelli, Jean-Pierre Mach, A. Tersikh, Ismat A Khatri
Publikováno v:
International Immunopharmacology. 57:112-120
We have shown that an altered tissue redox environment in mice lacking either murine beta Hemoglobin major (Hgbβ ma KO) or minor (Hgbβ mi KO) regulates inflammation. The REDOX environment in marrow stem cell niches also control differentiation path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544d09b1f4602d14b747b48e78ab3556
https://doi.org/10.1016/j.intimp.2018.02.010
https://doi.org/10.1016/j.intimp.2018.02.010
Autor:
Artur J. Ulmer, Alexey V. Terskikh, Zhiqi Chen, Ernst Th. Rietschel, Christian Alexander, Klaus Brandenburg, Adrian Heini, D Heumann, Ulrich Zähringer, Vienna Mazzoli, Jean-Pierre Mach, Reginald M. Gorczynski, Ismat A Khatri, Kai Yu
Publikováno v:
The Pharmacogenomics Journal. 18:546-555
Injections of a crude fetal sheep liver extract (FSLE) containing fetal hemoglobin, MPLA, and glutathione (GSSH) reversed cytokine changes in aged mice. To investigate the role of fetal hemoglobin we derived mice with homzygous deletions for either o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e08520f8a484d1c118696da39142b01
https://doi.org/10.1038/s41397-017-0008-y
https://doi.org/10.1038/s41397-017-0008-y
Autor:
Adrian Heini, Ismat A Khatri, Ulrich Zähringer, R.M. Gorczynski, Christian Alexander, Jean-Pierre Mach, D. Neumann, Ernst Th. Rietschel, Klaus Brandenburg, A. Tersikh, Artur J. Ulmer, Zhiqi Chen, Kai Yu
Publikováno v:
International Immunopharmacology. 50:69-76
C5BL/6 female mice receiving dextran sodium sulfate in their drinking water develop an acute inflammatory colitis within 7 d, with weight loss, histopathologic signs of inflammation, and colonic expression of inflammatory cytokines. In previous studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec08d99fa4e17e5293855a4616a5801
https://doi.org/10.1016/j.intimp.2017.06.003
https://doi.org/10.1016/j.intimp.2017.06.003
Autor:
Ismat A Khatri, Ulrich Zähringer, D Heumann, R.M. Gorczynski, Christian Alexander, Zhiqi Chen, O. Kos, Ernst Th. Rietschel, Klaus Brandenburg, Adrian Heini, Jean-Pierre Mach, Alexey V. Terskikh, Thierry Waelli, Kai Yu, Artur J. Ulmer
Publikováno v:
International immunopharmacology. 59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac95ba006bc5b9719a56e1c996b3a662
https://pubmed.ncbi.nlm.nih.gov/29477972
https://pubmed.ncbi.nlm.nih.gov/29477972
Autor:
Ismat A Khatri, Chung-Wai Chow, Amanda Sparkes, Reginald M. Gorczynski, Aaron Prodeus, Marzena Cydzik, Ashley Young, Eric Huang, Nicholas W. Fischer, Jean Gariépy, Lindsay Woo
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 350-358 (2018)
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 350-358 (2018)
Functional aptamers displaying agonistic or antagonistic properties are showing great promise as modulators of immune responses. Here, we report the development of a polyethylene glycol-modified (PEGylated) DNA aptamer as a cross-species (murine and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677d93ed68004028a0b942c10492c2ce
https://pubmed.ncbi.nlm.nih.gov/30195773
https://pubmed.ncbi.nlm.nih.gov/30195773
Autor:
Sameera Rahman, Rongquan Wang, Sherilyn L. Bell, Ismat A Khatri, Gongqiao Xu, Janet F. Forstner
Publikováno v:
Biochemical Journal. 373:893-900
Within the C-terminal domain of many secretory mucins is a ‘cystine knot’ (CK), which is needed for dimer formation in the endoplasmic reticulum. Previous studies indicate that in addition to an unpaired cysteine, the three intramolecular cystine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870949367a813166b73d5dc458db8db5
https://doi.org/10.1042/bj20030096
https://doi.org/10.1042/bj20030096
Publikováno v:
Biochemical Journal. 372:263-270
In a previous study we showed, by transient expression studies in COS-1 cells, that the C-terminal domain of rat intestinal membrane mucin Muc3 was cleaved between glycine and serine within a GSIVV (one-letter) amino acid sequence during its residenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823fac7018ba628161a729d89046c33d
https://doi.org/10.1042/bj20021333
https://doi.org/10.1042/bj20021333
Autor:
J. Thomas Lamont, K. Ramakrishnan Bhaskar, S Umadevi Sajjan, Janet F. Forstner, Ismat A Khatri, Catherine K Y Ho
Publikováno v:
Pediatric Research. 53:619-627
Cystic fibrosis (CF) patients develop chronic lung infections associated with airway obstruction by viscous and insoluble mucus secretions. Although mucus glycoproteins (mucins) are thought to be responsible for mucus plugs, other glycoconjugate comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897848cd9ec3c2aa3facaee48f15b761
https://doi.org/10.1203/01.pdr.0000054780.11755.b9
https://doi.org/10.1203/01.pdr.0000054780.11755.b9