Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ismail Talahari"'
Autor:
Sophie Simar-Meintières, Ismail Talahari, Fabrice Nesslany, Daniel Marzin, Nadia Zennouche, Esther-Nadège NKili-Mboui
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 630:28-41
The objective of this study was to determine the ability of the alkaline in vivo Comet assay (pH>13) to distinguish genotoxic carcinogens from epigenetic carcinogens when performed on freshly isolated kidney cells and to determine the possible interf
Publikováno v:
Environmental and molecular mutagenesis. 49(6)
The chelating agent nitrilotriacetic acid (NTA), classified as an epigenetic rodent carcinogen, was assessed in the in vivo rodent Comet assay on isolated kidney cells. Unexpected potent increases in DNA damage were obtained in both the short (3-6 hr