Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ismail Sebina"'
Autor:
Bodie Curren, Tufael Ahmed, Ridwan B. Rashid, Ismail Sebina, Md. Al Amin Sikder, Daniel R. Howard, Mariah Alorro, Md. Ashik Ullah, Alec Bissell, Muhammed Mahfuzur Rahman, Michael A. Pearen, Grant A. Ramm, Antiopi Varelias, Stefan Rose-John, Kelli P.A. MacDonald, Robert Hoelzle, Páraic Ó Cuív, Kirsten M. Spann, Paul G. Dennis, Simon Phipps
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114974- (2024)
Summary: A poor maternal diet during pregnancy predisposes the infant to severe lower respiratory tract infections (sLRIs), which, in turn, increases childhood asthma risk; however, the underlying mechanisms remain poorly understood. Here, we show th
Externí odkaz:
https://doaj.org/article/35ed73a82c044bd8a5ad26ee440d31fb
Autor:
Nataly Stylianou, Ismail Sebina, Nicholas Matigian, James Monkman, Hadeel Doehler, Joan Röhl, Mark Allenby, Andy Nam, Liuliu Pan, Anja Rockstroh, Habib Sadeghirad, Kimberly Chung, Thais Sobanski, Ken O'Byrne, Ana Clara Simoes Florido Almeida, Patricia Zadorosnei Rebutini, Cleber Machado‐Souza, Emanuele Therezinha Schueda Stonoga, Majid E Warkiani, Carlos Salomon, Kirsty Short, Lana McClements, Lucia deNoronha, Ruby Huang, Gabrielle T Belz, Fernando Souza‐Fonseca‐Guimaraes, Vicki Clifton, Arutha Kulasinghe
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 2, Pp n/a-n/a (2024)
Abstract Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus infection in pregnancy is associated with higher incidence of placental dysfunction, referred to by a few studies as a ‘preeclampsia‐like syndrome’. Howe
Externí odkaz:
https://doaj.org/article/c26444dbfdab4c58aeeef3df629fe26a
Autor:
Sam Manna, Julie McAuley, Jonathan Jacobson, Cattram D. Nguyen, Md. Ashik Ullah, Ismail Sebina, Victoria Williamson, E. Kim Mulholland, Odilia Wijburg, Simon Phipps, Catherine Satzke
Publikováno v:
mSphere, Vol 7, Iss 1 (2022)
ABSTRACT Streptococcus pneumoniae (the pneumococcus) is a leading cause of pneumonia in children under 5 years of age. Coinfection by pneumococci and respiratory viruses enhances disease severity. Little is known about pneumococcal coinfections with
Externí odkaz:
https://doaj.org/article/84f46a9e41554702bd5f8ef3bea73ca5
Autor:
Jasmin Akter, David S Khoury, Rosemary Aogo, Lianne I M Lansink, Arya SheelaNair, Bryce S Thomas, Pawat Laohamonthonkul, Clara P S Pernold, Matthew W A Dixon, Megan S F Soon, Lily G Fogg, Jessica A Engel, Trish Elliott, Ismail Sebina, Kylie R James, Deborah Cromer, Miles P Davenport, Ashraful Haque
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007599 (2019)
Plasmodium parasites invade and multiply inside red blood cells (RBC). Through a cycle of maturation, asexual replication, rupture and release of multiple infective merozoites, parasitised RBC (pRBC) can reach very high numbers in vivo, a process tha
Externí odkaz:
https://doaj.org/article/39969c1b306b4b6d93575b28a7501a6c
Autor:
Ismail Sebina, Simon Phipps
Publikováno v:
Viruses, Vol 12, Iss 8, p 808 (2020)
Acute viral bronchiolitis causes significant mortality in the developing world, is the number one cause of infant hospitalisation in the developed world, and is associated with the later development of chronic lung diseases such as asthma. A vaccine
Externí odkaz:
https://doaj.org/article/5c8ff66812bc457dac284cc8ec6602eb
Autor:
Ismail Sebina, Kylie R James, Megan S F Soon, Lily G Fogg, Shannon E Best, Fabian de Labastida Rivera, Marcela Montes de Oca, Fiona H Amante, Bryce S Thomas, Lynette Beattie, Fernando Souza-Fonseca-Guimaraes, Mark J Smyth, Paul J Hertzog, Geoffrey R Hill, Andreas Hutloff, Christian R Engwerda, Ashraful Haque
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005999 (2016)
Parasite-specific antibodies protect against blood-stage Plasmodium infection. However, in malaria-endemic regions, it takes many months for naturally-exposed individuals to develop robust humoral immunity. Explanations for this have focused on antig
Externí odkaz:
https://doaj.org/article/a54be06609244dfbb023d5a998aed957
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106796 (2014)
Accurate biomarkers of Mycobacterium tuberculosis infection activity would significantly improve early diagnosis, treatment and management of M. tuberculosis infection. We hypothesised that circulating B-lymphocytes may be useful biomarkers of tuberc
Externí odkaz:
https://doaj.org/article/2644d2d922284de9a665ca22837d010f
Autor:
Ismail Sebina, Jacqueline M Cliff, Steven G Smith, Sarah Nogaro, Emily L Webb, Eleanor M Riley, Hazel M Dockrell, Alison M Elliott, Julius C R Hafalla, Stephen Cose
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51381 (2012)
The role of T-cells in immunity against Mycobacterium tuberculosis (M. tuberculosis) infection has been extensively studied, however, that of B-cells still remains comparatively unexplored. In this study, we determined the presence and frequencies of
Externí odkaz:
https://doaj.org/article/371d2245b60c43a6833ba286ab54f6b9
Autor:
Gyaviira Nkurunungi, Jimreeves E Lutangira, Swaib A Lule, Hellen Akurut, Robert Kizindo, Joseph R Fitchett, Dennison Kizito, Ismail Sebina, Lawrence Muhangi, Emily L Webb, Stephen Cose, Alison M Elliott
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47340 (2012)
BACKGROUND:Children with latent tuberculosis infection (LTBI) represent a huge reservoir for future disease. We wished to determine Mycobacterium tuberculosis (M.tb) infection prevalence among BCG-immunised five-year-old children in Entebbe, Uganda,
Externí odkaz:
https://doaj.org/article/fb4e65bf533944a4a706c308ef5b7304
Autor:
Ismail Sebina, Ridwan B. Rashid, Md. Al Amin Sikder, Muhammed Mahfuzur Rahman, Tufael Ahmed, Daniel E. Radford-Smith, Sergei V. Kotenko, Geoffrey R. Hill, Tobias Bald, Simon Phipps
Publikováno v:
The Journal of Immunology. 208:2806-2816
Infants with attenuated type III IFN (IFN-λ) responses are at increased risk of severe lower respiratory tract infection (sLRI). The IL-28Rα–chain and IL-10Rβ–chain form a heterodimeric receptor complex, necessary for IFN-λ signaling. Therefo