Investigating the potential of mono-chalcone compounds in targeting breast cancer receptors through network pharmacology, molecular docking, molecular dynamics simulation, antiproliferative effects, and gene expressions.

Autor: Ismail NZ; School of Chemical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia., Khairuddean M; School of Chemical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia., Alidmat MM; Faculty of Pharmacy, Jadara University, Irbid, 21110 Jordan., Abubakar S; School of Chemical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.; Department of Pure and Industrial Chemistry, Bayero University Kano, Kano, 3011 Nigeria., Arsad H; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200 Kepala Batas, Penang Malaysia.

Publikováno v: 3 Biotech [3 Biotech] 2024 Jun; Vol. 14 (6), pp. 151. Date of Electronic Publication: 2024 May 10.

Molecular docking and molecular dynamic simulations of apoptosis proteins with potential anticancer compounds present in Clinacanthus nutans extract using gas chromatography-mass spectrometry.

Autor: Ismail NZ; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia., Mohamed WAS; Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur, Malaysia.; Centre for Coordination of Clinical Research Network, National Institute of Health, Shah Alam, Malaysia., Ab Rahim N; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia.; Faculty of Health Sciences, Universiti Teknologi MARA, Penang, Malaysia., Hashim NM; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia., Adebayo IA; Microbiology and Immunology Department, School of Biomedical Sciences, Kampala International University, Ishaka, Uganda.; Analystical Biochemistry Research Centre, Universiti Sains Malaysia, Penang, Malaysia., Mohamad Zain NN; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia., Arsad H; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2023 Aug-Sep; Vol. 41 (13), pp. 6104-6120. Date of Electronic Publication: 2022 Jul 27.

Q-TOF LC-MS compounds evaluation of propolis extract derived from Malaysian stingless bees, Tetrigona apicalis , and their bioactivities in breast cancer cell, MCF7.

Autor: Mohamed WAS; Centre for Coordination of Clinical Research Network (CCRN), Block B4, Institute for Clinical Research (ICR), National Institutes of Health (NIH), Jalan Setia Murni U13/52, Seksyen U13, Setia Alam, 40170 Shah Alam, Selangor, Malaysia.; Centre for Clinical Trial (CCT), Block B4, Institute for Clinical Research (ICR), National Institutes of Health (NIH), Jalan Setia Murni U13/52, Seksyen U13, Setia Alam, 40170 Shah Alam, Selangor, Malaysia., Ismail NZ; Department of Toxicology, Advanced Medical and Dental Institute (IPPT) Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Muhamad M; Department of Toxicology, Advanced Medical and Dental Institute (IPPT) Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Omar EA; Department of Toxicology, Advanced Medical and Dental Institute (IPPT) Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Abdul Samad N; Department of Toxicology, Advanced Medical and Dental Institute (IPPT) Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Ooi JP; Department of Toxicology, Advanced Medical and Dental Institute (IPPT) Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia.; Breast Cancer Translational Research Program (BCTRP@IPPT), Advanced Medical and Dental Institute (IPPT), Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Mohamad S; Department of Toxicology, Advanced Medical and Dental Institute (IPPT) Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia.; Breast Cancer Translational Research Program (BCTRP@IPPT), Advanced Medical and Dental Institute (IPPT), Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia.

Publikováno v: Saudi journal of biological sciences [Saudi J Biol Sci] 2022 Oct; Vol. 29 (10), pp. 103403. Date of Electronic Publication: 2022 Aug 05.

Christia vespertilionis extract induced antiproliferation and apoptosis in breast cancer (MCF7) cells.

Autor: Ismail NZ; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas, 13200, Penang, Malaysia., Adebayo IA; Microbiology and Immunology Department, School of Biomedical Sciences, Kampala International University, Western Campus, P.O. Box 71, Ishaka, Bushenyi, Uganda.; Analystical Biochemistry Research Centre, Universiti Sains Malaysia, Penang, Malaysia., Mohamed WAS; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas, 13200, Penang, Malaysia.; Institute of Medical Research, National Institute of Health, Persiaran Setia Murni, Setia Alam, 40170, Shah Alam, Selangor, Malaysia., Mohamad Zain NN; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas, 13200, Penang, Malaysia., Arsad H; Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas, 13200, Penang, Malaysia. hasniarsad@usm.my.

Publikováno v: Molecular biology reports [Mol Biol Rep] 2021 Nov; Vol. 48 (11), pp. 7361-7370. Date of Electronic Publication: 2021 Oct 19.

GC-MS Evaluation, Antioxidant Content, and Cytotoxic Activity of Propolis Extract from Peninsular Malaysian Stingless Bees, Tetrigona Apicalis .

Autor: Mohamed WAS; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Ismail NZ; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Omar EA; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Abdul Samad N; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia., Adam SK; Pharmacology Unit, Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Mohamad S; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, SAINS@BERTAM, 13200 Kepala Batas, Penang, Malaysia.

Publikováno v: Evidence-based complementary and alternative medicine : eCAM [Evid Based Complement Alternat Med] 2020 Dec 09; Vol. 2020, pp. 8895262. Date of Electronic Publication: 2020 Dec 09 (Print Publication: 2020).