Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ismail Ghazzouli"'
Autor:
R. R. Ii Webb, Ismail Ghazzouli, John C. Martin, Michael J. M. Hitchcock, J. J. Bronson, E. R. Kern
Publikováno v:
ChemInform. 22
Autor:
Joanne J. Bronson, E. R. Kern, John C. Martin, Choung U. Kim, Michael J. M. Hitchcock, Ismail Ghazzouli
Publikováno v:
ChemInform. 22
Publikováno v:
ChemInform. 22
Several 2'-fluoroarabino-2',3'-dideoxy- and 2'-fluoro-2',3'-unsaturated 2',3'-dideoxy pyrimidine nucleoside analogues are reported. The saturated analogues 1-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)thymine (2'-threo-FddT, 33), 1-(2,3-dideox
Autor:
Choung U. Kim, John C. Martin, M. J. M. Hitchcook, Peter F. Misco, Ismail Ghazzouli, Bing-Yu Luh
Publikováno v:
ChemInform. 23
Autor:
John W. Russell, J. E. Jun. Starrett, M. M. Mansuri, Valerie J. Whiterock, John C. Martin, Ismail Ghazzouli, David R. Tortolani, J. M. Hitchcock
Publikováno v:
ChemInform. 25
Autor:
Muzammil M. Mansuri, Ismail Ghazzouli, Lisa M. Dunkle, John C. Martin, Sterzycki Roman Z, Michael J. M. Hitchcock, Sanjeev Kaul, Arnold Fridland
Publikováno v:
Annals of the New York Academy of Sciences. 616:22-28
Autor:
Joanne J. Bronson, Choung U. Kim, Ismail Ghazzouli, Peter F. Misco, J. C. Martin, Bing Yu Luh, Michael J. M. Hitchcock
Publikováno v:
Journal of Medicinal Chemistry. 33:1207-1213
A series of 9-(phosphonoalkyl)purines, which are analogues of 9-[2-(phosphonomethoxy)ethyl]purines (guanine, PMEG, 1; adenine, PMEA, 2), were synthesized. The analogues were tested for activity against herpes simplex virus types 1 and 2 (HSV-1 and HS
Autor:
Michael J. M. Hitchcock, R. A. Buroker, C. L. Bregman, Sterzycki Roman Z, J. Desiderio, Ismail Ghazzouli, J. E. Jun. Starrett, John C. Martin, Muzammil M. Mansuri
Publikováno v:
Antimicrobial Agents and Chemotherapy. 34:637-641
Three analogs of thymidine, D4T [2',3'-didehydro-2',3'-dideoxythymidine; 1-(2,3-dideoxy-beta-D-glyceropent-2-enofuranosyl)thymine], FddT (3'-fluoro-3'-deoxythymidine), and AZT (3'-azido-3'-deoxythymidine), were compared in biological tests designed t
Autor:
Michael J. M. Hitchcock, Choung U. Kim, Ismail Ghazzouli, Peter F. Misco, Bing Yu Luh, John C. Martin
Publikováno v:
Journal of medicinal chemistry. 34(7)
Novel phosphonate isosteres of acyclovir (ACV) and ganciclovir (DHPG) monophosphates were found to be potent and selective antiherpesvirus agents. In the series of phosphonate analogues of ACV monophosphate, only the guanine analogue 20 exhibited act
Autor:
Choung U. Kim, Joanne J. Bronson, Michael J. M. Hitchcock, Bing Yu Luh, J. C. Martin, Peter F. Misco, Ismail Ghazzouli
Publikováno v:
ChemInform. 21
A series of 9-(phosphonoalkyl)purines, which are analogues of 9-[2-(phosphonomethoxy)ethyl]purines (guanine, PMEG, 1; adenine, PMEA, 2), were synthesized. The analogues were tested for activity against herpes simplex virus types 1 and 2 (HSV-1 and HS