Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ismail Chouchane, A"'
Autor:
Lotfi Chouchane, Jean-Charles Grivel, Elmoubasher Abu Baker Abd Farag, Igor Pavlovski, Selma Maacha, Abbirami Sathappan, Hamad Eid Al-Romaihi, Sirin W.J. Abuaqel, Manar Mahmoud Ahmad Ata, Aouatef Ismail Chouchane, Sami Remadi, Najeeb Halabi, Arash Rafii, Mohammed H. Al-Thani, Nico Marr, Murugan Subramanian, Jingxuan Shan
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
The development of prophylactic and therapeutic agents for coronavirus disease 2019 (COVID-19) is a current global health priority. Here, we investigated the presence of cross-neutralizing antibodies against severe acute respiratory syndrome coronavi
Externí odkaz:
https://doaj.org/article/78735e02d86248bba861c7d04c9abd1f
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(11)
Melanocyte survival is mediated by diverse signaling pathways. However, the molecular mechanisms they use and molecules that they target are incompletely understood. Here, we show that melanocyte survival is mediated by diverse, nonredundant signalin
Autor:
Meenakshi, Umar, Andre, Megarbane, Jingxuan, Shan, Najeeb, Syed, Eliane, Chouery, Elbay, Aliyev, Puthen, Jithesh, Ramzi, Temanni, Issam, Mansour, Lotfi, Chouchane, Aouatef, Ismail Chouchane
Publikováno v:
Journal of Cellular and Molecular Medicine
Familial Mediterranean fever (FMF) is the most common auto‐inflammatory disease. It is transmitted as autosomal recessive trait with mutations in MEditerranean FeVer (MEFV) gene. Despite a typical clinical expression, many patients have either a si
Autor:
Wei Liu, Lotfi Chouchane, Aouatef Ismail Chouchane, Valeria De Giorgi, Rebecca Mathew, Davide Bedognetti, Konduru S Sastry, Sara Tomei, Daniela Murtas, Lee Silcock, Francesco M. Marincola, Ena Wang, Nicola James, Muna Al Hashmi, Ramzi Temanni, Valentina Mattei, Barbara Seliger
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Background Most mutations in melanoma affect one critical amino acid on BRAF gene, resulting in the V600E substitution. Patient management is often based on the use of specific inhibitors targeting this mutation. Methods DNA and RNA mutation status w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5efe0635c126ac8449b88895393f0f2
https://doi.org/10.21203/rs.3.rs-16973/v1
https://doi.org/10.21203/rs.3.rs-16973/v1
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1618 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The classical function of Vitamin D, which involves mineral balance and skeletal maintenance, has been known for many years. With the discovery of vitamin D receptors in various tissues, several other biological functions of vitamin D are increasingl
Autor:
M K Al-Kowari, Dhanya Kizhakayil, Lotfi Chouchane, A Haoudi, A Ismail Chouchane, Pu Li, George Kulik, Ena Wang, M A Al-Muftah, Konduru S Sastry, Francesco M. Marincola
Publikováno v:
Cell Death & Differentiation. 21:1936-1949
Emerging evidence suggests that the resistance of cancer stem cells (CSC) to many conventional therapies is one of the major limiting factors of cancer therapy efficacy. Identification of mechanisms responsible for survival and self-renewal of CSC wi
Autor:
Umar, Meenakshi, Megarbane, Andre, Shan, Jingxuan, Syed, Najeeb, Chouery, Eliane, Aliyev, Elbay, Jithesh, Puthen, Temanni, Ramzi, Mansour, Issam, Chouchane, Lotfi, Ismail Chouchane, Aouatef
Publikováno v:
Journal of Cellular & Molecular Medicine; Oct2020, Vol. 24 Issue 19, p11294-11306, 13p
Autor:
Wei Liu, Ramzi Temanni, Puthen V. Jithesh, Remy Hobeika, Yvette Macary, Konduru S Sastry, Nancy Choucair, Monko Lek, Rashid Al-Ali, Aouatef Ismail Chouchane, Lotfi Chouchane, Ena Wang, Daniel G. MacArthur, Moncef M. Ladjimi, Francesco M. Marincola, Catherine M. Rose, Remy Thomas, André Mégarbané, Sara Tomei
Publikováno v:
BMC Medical Genetics
Background KCNH1 encodes a voltage-gated potassium channel that is predominantly expressed in the central nervous system. Mutations in this gene were recently found to be responsible for Temple-Baraitser Syndrome (TMBTS) and Zimmermann-Laband syndrom
Autor:
Ena Wang, Konduru S Sastry, Aouatef Ismail Chouchane, Francesco M. Marincola, Lotfi Chouchane
Publikováno v:
Qatar Foundation Annual Research Conference Proceedings Volume 2016 Issue 1.
BackgroundVasoactive intestinal peptide (VIP) is a neuropeptide that controls the proliferation, differentiation, and survival of various normal and cancer cells. Elevated expression of VIP receptors has been found in prostate and breast cancer; and
Autor:
Konduru S Sastry, George Kulik, Francesco M. Marincola, Lotfi Chouchane, Ena Wang, Aouatef Ismail Chouchane
Publikováno v:
Cell Death & Disease
Cancer stem cells (CSCs) are increasingly considered to be responsible for tumor initiation, metastasis and drug resistance. The drug resistance mechanisms activated in CSCs have not been thoroughly investigated. Although neuropeptides such as vasoac