Time- and sex-dependent efficacy of magnesium sulfate to prevent behavioral impairments and cerebral damage in a mouse model of cerebral palsy

Autor: Ismaël Daher, Bérénice Le Dieu-Lugon, Maryline Lecointre, Nicolas Dupré, Caroline Voisin, Philippe Leroux, Nathalie Dourmap, Bruno J. Gonzalez, Stéphane Marret, Isabelle Leroux-Nicollet, Carine Cleren

Publikováno v: Neurobiology of Disease, Vol 120, Iss , Pp 151-164 (2018)

Cerebral lesions acquired in the perinatal period can induce cerebral palsy (CP), a multifactorial pathology leading to lifelong motor and cognitive deficits. Several risk factors, including perinatal hypoxia-ischemia (HI), can contribute to the emer

Externí odkaz: https://doaj.org/article/58c9580e690c4f84ab5456a36d738e29

Magnesium Sulfate Prevents Neurochemical and Long-Term Behavioral Consequences of Neonatal Excitotoxic Lesions: Comparison Between Male and Female Mice

Autor: Lauriane Ramet, Cathy Gomila, Bruno J. Gonzalez, Jérôme Ausseil, Philippe Leroux, Ismaël Daher, Bérénice Le Dieu-Lugon, Vincent Roy, Isabelle Leroux-Nicollet, Matthieu Jean Alexandre Lecuyer, Nathalie Dourmap, Salah El Mestikawy, Stéphanie Daumas, Stéphane Marret, Carine Cleren

Publikováno v: Journal of Neuropathology and Experimental Neurology
Journal of Neuropathology and Experimental Neurology, Lippincott, Williams & Wilkins, 2017, 76 (10), pp.883-897. ⟨10.1093/jnen/nlx073⟩
Journal of Neuropathology and Experimental Neurology, 2017, 76 (10), pp.883-897. ⟨10.1093/jnen/nlx073⟩
BASE-Bielefeld Academic Search Engine

Magnesium sulfate (MgSO4) administration to mothers at risk of preterm delivery is proposed as a neuroprotective strategy against neurological alterations such as cerebral palsy in newborns. However, long-term beneficial or adverse effects of MgSO4 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cf2d138cf164645073bcb97f6b7d44
https://hal.archives-ouvertes.fr/hal-01662388