Vascularization of purified pancreatic islet-like cell aggregates (pseudoislets) after syngeneic transplantation

Autor: Peter Vajkoczy, Michael D. Menger, Vincenzo Cirulli, C. Beger, Philippe A. Halban

Publikováno v: Diabetes, Vol. 47, No 4 (1998) pp. 559-565

To clarify whether avascular purified endocrine cell aggregates derived from islets of Langerhans (pseudoislets) revascularize similarly to what is known for intact pancreatic islet grafts, we studied the process of angiogenesis and revascularization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b790deab80f5f14843fd70846c9736
https://doi.org/10.2337/diabetes.47.4.559

Influence of donor age on islet isolation and transplantation outcome

Autor: Pierre-Yves Benhamou, Thierry Berney, Christian Toso, Géraldine Parnaud, Lionel Badet, Sandrine Demuylder-Mischler, Laurianne Giovannoni, Philippe Morel, Laure Milliat-Guittard, Yannick D. Muller, Raphael P. H. Meier, Cyrille Colin, Nadja Niclauss, Domenico Bosco, Coralie Brault

Publikováno v: Transplantation
Transplantation, 2011, 91 (3), pp.360-6
Transplantation, Lippincott, Williams & Wilkins, 2011, 91 (3), pp.360-6
Transplantation, Vol. 91, No 3 (2011) pp. 360-6

International audience; BACKGROUND: It has been suggested that the age of human organ donors might influence islet isolation and transplantation outcome in a negative way due to a decrease of in vivo function in islets isolated from older donors. MET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b3ed1c81217725f7f1fc8572f8d61c
https://www.hal.inserm.fr/inserm-00628798

Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success

Autor: Peter A. Senior, Angela Koh, Tatsuya Kin, Parastoo Dinyari, Sharleen Imes, Olle Korsgren, Abdul Salam, A. M. James Shapiro, Andrew J. Malcolm, Bo Nilsson, Christian Toso

Publikováno v: Transplantation, Vol. 89, No 4 (2010) pp. 465-471

BACKGROUND: Successful islet transplantation can result in insulin independence in many patients with type 1 diabetes mellitus, but it often requires more than one islet infusion. The ability to achieve insulin independence with a single donor is an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf147e82b15abecf09deb2d8985d6555
https://pubmed.ncbi.nlm.nih.gov/20177350

Reduction of blood glucose variability in type 1 diabetic patients treated by pancreatic islet transplantation: interest of continuous glucose monitoring

Autor: Laurence, Kessler, Raphael, Passemard, Jose, Oberholzer, Pierre Yves, Benhamou, Pascal, Bucher, Christian, Toso, Pierre, Meyer, Alfred, Penfornis, Lionel, Badet, Philippe, Wolf, Cyrille, Colin, Philippe, Morel, Michel, Pinget

Publikováno v: Diabetes Care, Vol. 25, No 12 (2002) pp. 2256-62

To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA).The CGMS enabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1f6bd9a1b4a5d05e5a00c9e6ae51b1e
https://archive-ouverte.unige.ch/unige:46204

Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis

Autor: Berney, T., Molano, R. D., Cattan, P., Antonello Pileggi, Vizzardelli, C., Oliver, R., Ricordi, C., Inverardi, L.

Publikováno v: Transplantation, Vol. 71, No 1 (2001) pp. 125-32
Scopus-Elsevier

Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet transplants. Evidence is accumulating to single out endotoxin contamination of the various reagents needed for islet isolation as a major

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6a9313f328511f1b3d6c7262110d1977
https://archive-ouverte.unige.ch/unige:47294