Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Islets of Langerhans/immunology/pathology/virology"'
Publikováno v:
The Journal of experimental medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 209, no. 10, pp. 1769-1779
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 209, No 10 (2012) pp. 1769-79
Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 209, no. 10, pp. 1769-1779
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 209, No 10 (2012) pp. 1769-79
Autoimmunity occurs because central and peripheral tolerance mechanisms fail to tolerize T cells with weak self-reactivity to tissue-restricted antigen.
Central and peripheral tolerance prevent autoimmunity by deleting the most aggressive CD8+ T
Central and peripheral tolerance prevent autoimmunity by deleting the most aggressive CD8+ T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7db3bc3cecf0a23fb2580ed43a798b
http://resolver.sub.uni-goettingen.de/purl?gs-1/10626
http://resolver.sub.uni-goettingen.de/purl?gs-1/10626
Autor:
Monika Bayer, Beat A. Imhof, Michel Aurrand-Lions, Martin Holdener, Selina Christen, Matthias von Herrath, Ken Coppieters, Urs Christen, Edith Hintermann, Josef Pfeilschifter, Kerstin Rose
Publikováno v:
PloS one
PLoS ONE, Vol 8, Iss 1, p e54675 (2013)
PLOS ONE, Vol. 8, No 1 (2013) P. e54675
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e54675 (2013)
PLOS ONE, Vol. 8, No 1 (2013) P. e54675
PLoS ONE
Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. Recruitment of inflammatory cells is prerequisite to beta-cell-injury. The junctional adhesion molecule (JAM) family proteins JAM-B and JAM