Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Islam T. M. Hussein"'
Autor:
Eric G. Romanowski, Islam T. M. Hussein, Steven C. Cardinale, Michelle M. Butler, Lucas R. Morin, Terry L. Bowlin, Kathleen A. Yates, Robert M. Q. Shanks, Regis P. Kowalski
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 294 (2021)
Presently, there is no FDA- or EMA-approved antiviral for the treatment of human adenovirus (HAdV) ocular infections. This study determined the antiviral activity of filociclovir (FCV) against ocular HAdV isolates in vitro and in the Ad5/NZW rabbit o
Externí odkaz:
https://doaj.org/article/f4aedeca347e483ea6d1012c90d03a5e
Autor:
Michael A Estrin, Islam T M Hussein, Wendy B Puryear, Anne C Kuan, Stephen C Artim, Jonathan A Runstadler
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197246 (2018)
Influenza A virus infections are important causes of morbidity and mortality worldwide, and currently available prevention and treatment methods are suboptimal. In recent years, genome-wide investigations have revealed numerous host factors that are
Externí odkaz:
https://doaj.org/article/4e6860334e0f4c8ab885debf9c491772
Autor:
Justin Bahl, Truc T Pham, Nichola J Hill, Islam T M Hussein, Eric J Ma, Bernard C Easterday, Rebecca A Halpin, Timothy B Stockwell, David E Wentworth, Ghazi Kayali, Scott Krauss, Stacey Schultz-Cherry, Robert G Webster, Richard J Webby, Michael D Swartz, Gavin J D Smith, Jonathan A Runstadler
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005620 (2016)
Despite evidence for avian influenza A virus (AIV) transmission between wild and domestic ecosystems, the roles of bird migration and poultry trade in the spread of viruses remain enigmatic. In this study, we integrate ecosystem interactions into a p
Externí odkaz:
https://doaj.org/article/1c62a5097cbc409cafaa0e23037ab469
Publikováno v:
Antiviral Research. 208:105431
Clusters of acute non HepA-E hepatitis cases in previously healthy children have been reported globally. At least, 1010 cases were identified in 35 countries, 5% of those cases required liver transplantation and 2% died. The exact cause is not yet kn
Autor:
Jacqueline F. Spencer, Karoly Toth, Baoling Ying, Ann E. Tollefson, Mark N. Prichard, William S. M. Wold, Islam T. M. Hussein, Terry L. Bowlin, Scott H. James, Jessica Eagar
Publikováno v:
Antimicrob Agents Chemother
Human adenovirus (HAdV) infection is common in the general population and can cause a range of clinical manifestations, among which pneumonia and keratoconjunctivitis are the most common. Although HAdV infections are mostly self-limiting, infections
Publikováno v:
Antiviral research. 176
Human cytomegalovirus (HCMV) infections are widespread among the human population. Infection is persistent and mostly asymptomatic, except in immunocompromised individuals, particularly transplant patients, where significant morbidity and mortality c
Autor:
Rachel Coleman, Qi Chen, Ashley Archer, Chong Liu, Islam T. M. Hussein, Stewart W. Schneller, Terry L. Bowlin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2480-2482
Enantiomeric 3-deaza-1′,6′-isoneplanocins (C-3 unsubstituted 7a/7b and C-3 with a bromine 8a/8b) lacking the 4′-hydroxymethyl as mechanistically designed anti-viral targets have been prepared by utilizing the Ullmann reaction. Anti-Ebola proper
Autor:
Xudong Lin, Wendy B. Puryear, Andrew M. Ramey, David L. Suarez, Nadia Fedorova, Walter M. Boyce, Kimberly R. Davis, Rebecca A. Halpin, Nichola J. Hill, Timothy J. Spivey, Islam T. M. Hussein, Jonathan A. Runstadler, Eric J. Ma, Suman R. Das
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 4, Pp 654-657 (2017)
Emerging Infectious Diseases
Emerging infectious diseases, vol 23, iss 4
Emerging Infectious Diseases
Emerging infectious diseases, vol 23, iss 4
Sampling of mallards in Alaska during September 2014-April 2015 identified low pathogenic avian influenza A virus (subtypes H5N2 and H1N1) that shared ancestry with highly pathogenic reassortant H5N2 and H5N1 viruses. Molecular dating indicated reass
Autor:
Brian G. Gentry, Michelle M. Butler, Gloria Komazin-Meredith, Anna C. Burns, John D. Williams, Kathryn J. Vollmer, Steve Cardinale, Islam T. M. Hussein, Zachary D. Aron, Hannah E. Sauer, Terry L. Bowlin, Marc Busch
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
To determine the mechanism of action of third-generation methylenecyclopropane nucleoside analogs (MCPNAs), DNA sequencing of herpes simplex virus 1 (HSV-1) isolates resistant to third-generation MCPNAs resulted in the discovery of G841S and N815S mu
Autor:
Islam T. M. Hussein, Jonathan A. Runstadler, Eric J. Ma, Randy A. Albrecht, Brandt W. Meixell, Mark S. Lindberg, Justin Bahl, Nichola J. Hill
Publikováno v:
PMC
© 2016. H9N2 influenza A viruses are on the list of potentially pandemic subtypes. Therefore, it is important to understand how genomic reassortment and genetic polymorphisms affect phenotypes of H9N2 viruses circulating in the wild bird reservoir.