Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Islam El-Awaad"'
Autor:
Lukas Ernst, Hui Lyu, Pi Liu, Christian Paetz, Hesham M. B. Sayed, Tomke Meents, Hongwu Ma, Ludger Beerhues, Islam El-Awaad, Benye Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Medicinal compounds from plants include bicyclo[3.3.1]nonane derivatives, the majority of which are polycyclic polyprenylated acylphloroglucinols (PPAPs). Prototype molecules are hyperforin, the antidepressant constituent of St. John’s wor
Externí odkaz:
https://doaj.org/article/a003b11df86e41e48e9d387fdd9bb87a
Publikováno v:
Frontiers in Catalysis, Vol 4 (2024)
Externí odkaz:
https://doaj.org/article/a7295aab27514c74b7cc8ca2a5b7124f
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Xanthones are pharmacologically and biosynthetically intriguing compounds. Here, the authors identify two cytochrome P450 enzymes, which hydroxylate and cyclize the benzophenone precursor to either 1,3,7- or 1,3,5-trihydroxyxanthones, and pinpoint re
Externí odkaz:
https://doaj.org/article/24ea258c94a0425394112027bfe0fec6
Autor:
Tobias Fiesel, Mariam Gaid, Andreas Müller, Joana Bartels, Islam El-Awaad, Till Beuerle, Ludger Ernst, Sönke Behrends, Ludger Beerhues
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 15616-15630 (2015)
In plants, prenylation of metabolites is widely distributed to generate compounds with efficient defense potential and distinct pharmacological activities profitable to human health. Prenylated compounds are formed by members of the prenyltransferase
Externí odkaz:
https://doaj.org/article/e98a6c3c8cd94886bf27ea871dc626eb
Publikováno v:
Plant Physiology.
Polyprenylated xanthones are natural products with a multitude of biological and pharmacological activities. However, their biosynthetic pathway is not completely understood. In this study, metabolic profiling revealed the presence of 4-prenylated 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4ca4b197bb9336edaa3ff92aa392e6b
https://doi.org/10.1093/plphys/kiad219
https://doi.org/10.1093/plphys/kiad219
Autor:
Elisabeth Gau, Ulrich Schwaneberg, Falco Jung, Islam El-Awaad, Maximilian Nöth, Andrij Pich, Mehdi D. Davari
Publikováno v:
Green Chemistry. 22(23):8183-8209
Enzymes are nature's catalysts and have great potential for sustainable processes from renewable resources. The adaptation of enzymes to the requirements of industrial processes is a prerequisite to harness their benefits in large-scale transformatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65168a89c935528f4b6434fecda595bb
https://doi.org/10.1039/d0gc03229h
https://doi.org/10.1039/d0gc03229h
Autor:
Ulrich Schwaneberg, Larissa Hussmann, Thomke Belthle, Andrij Pich, Mehdi D. Davari, Felix Jakob, Islam El-Awaad, Maximilian Nöth
Publikováno v:
Biomacromolecules, 21(12), 5128-5138. American Chemical Society
Microgels are an emerging class of "ideal" enzyme carriers because of their chemical and process stability, biocompatibility, and high enzyme loading capability. In this work, we synthesized a new type of permanently positively charged poly(N-vinylca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35988ef59627a33ef85c90dda2275598
https://doi.org/10.1021/acs.biomac.0c01262
https://doi.org/10.1021/acs.biomac.0c01262
Publikováno v:
Bioconjugate Chemistry, 30(11), 2859-2869. American Chemical Society
Enzyme immobilization has been widely used to improve the stability and recyclability of enzymes in industrial processes. In this work, a sortase-mediated and therefore selective covalent immobilization strategy (sortagging) for enzymes on microgels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27fa6e4b1c9748ae7be7314e53fea35
https://doi.org/10.1021/acs.bioconjchem.9b00568
https://doi.org/10.1021/acs.bioconjchem.9b00568
Autor:
Mariam Gaid, Ute Wittstock, Tobias Fiesel, Mohamed M. S. Nagia, Eline Biedermann, Ludger Beerhues, Robert Hänsch, Islam El-Awaad
Publikováno v:
New Phytologist. 222:318-334
Polyprenylated acylphloroglucinol derivatives, such as xanthones, are natural plant products with interesting pharmacological properties. They are difficult to synthesize chemically. Biotechnological production is desirable but it requires an underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1bd0e44e575b49f7559689f27f8d5e
https://doi.org/10.1111/nph.15611
https://doi.org/10.1111/nph.15611
Autor:
Maximilian Nöth, Islam El-Awaad, Guilherme Dilarri, Ulrich Schwaneberg, Felix Jakob, Letícia Celia de Lencastre Novaes, Zhi Zou, Mehdi D. Davari, Henrique Ferreira
Publikováno v:
Biotechnology & bioengineering 118(4), 1520-1530 (2021). doi:10.1002/bit.27666
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Biotechnology & bioengineering (2021). doi:10.1002/bit.27666
Published by Wiley, New York, NY [u.a.]
Published by Wiley, New York, NY [u.a.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ff46841df83f0cca7b5620f6f2c427
https://pubmed.ncbi.nlm.nih.gov/33404092
https://pubmed.ncbi.nlm.nih.gov/33404092