Development of Cu( ii )-specific peptide shuttles capable of preventing Cu–amyloid beta toxicity and importing bioavailable Cu into cells

Autor: Michael Okafor, Paulina Gonzalez, Pascale Ronot, Islah El Masoudi, Anne Boos, Stéphane Ory, Sylvette Chasserot-Golaz, Stéphane Gasman, Laurent Raibaut, Christelle Hureau, Nicolas Vitale, Peter Faller

Publikováno v: Chemical Science
Chemical Science, 2022, 13 (40), pp.11829-11840. ⟨10.1039/d2sc02593k⟩

Copper (Cu) in its ionic forms is an essential element for mammals and its homeostasis is tightly controlled. Accordingly, Cu-dyshomeostasis can be lethal as is the case in the well-established genetic Wilson's and Menkes diseases. In Alzheimer's dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891ef5d34d355021b6c40a27716aeb5b
https://hal.science/hal-03876781/file/d2sc02593k.pdf

Consequences of trace metal cocktail exposure in zebra finch (Taeniopygia guttata) and effect of calcium supplementation

Autor: Sylvie Massemin, Sandrine Zahn, Anne Boos, Agnès Saulnier, Pascale Ronot, Mirella Del Nero, Islah El Masoudi, Josefa Bleu

Publikováno v: Ecotoxicology and Environmental Safety
Ecotoxicology and Environmental Safety, Elsevier, 2020, 193, pp.110357. ⟨10.1016/j.ecoenv.2020.110357⟩
Ecotoxicology and Environmental Safety, Elsevier, 2020
HAL

International audience; Trace metal elements are significant stressors in urban areas. Their harmful effects on physiological parameters are demonstrated, but current laboratory studies are not representative of wild chronic exposure to a trace metal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a967d50d52e747ae72213f6811c33ef
https://hal.archives-ouvertes.fr/hal-02555743