Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Iskandar F. Abdullaev"'
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12304 (2010)
Gliomas are morbid brain tumors that are extremely resistant to available chemotherapy and radiology treatments. Some studies have suggested that calcium-activated potassium channels contribute to the high proliferative potential of tumor cells, incl
Externí odkaz:
https://doaj.org/article/a5b8fc2c5c7444e0bbbef7d4d1dcf332
Publikováno v:
Biochemical Journal. 458:575-583
The Bestrophin family is composed of four human genes that form transmembrane proteins [1-3]. When heteroexpressed in HEK293 cells, all four human Bestrophin genes produce novel and unique Cl− anion currents [4,5]. Mutations in one family member, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd845c43c85774c86cf9dc5e90ea18cb
https://doi.org/10.1042/bj20121546
https://doi.org/10.1042/bj20121546
Autor:
Matthew M. Henkel, María C. Hyzinski-García, Iskandar F. Abdullaev, Mohamed Trebak, Rajender K. Motiani, Yu Hung Kuo, Xuexin Zhang, Khalid Matrougui, Alexander A. Mongin
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:1249-1260
The Ca(2+) sensor stromal interacting molecule 1 (STIM1) and the Ca(2+) channel Orai1 mediate the ubiquitous store-operated Ca(2+) entry (SOCE) pathway activated by depletion of internal Ca(2+) stores and mediated through the highly Ca(2+)-selective,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ec851964645b4ac8002f2faf762b42
https://doi.org/10.1007/s00424-013-1254-8
https://doi.org/10.1007/s00424-013-1254-8
Autor:
Harold A. Singer, Roman Ginnan, Zhen Wang, Peter A. Vincent, Iskandar F. Abdullaev, Mohamed Trebak
Publikováno v:
Journal of Biological Chemistry. 285:21303-21312
Multiple Ca(2+) release and entry mechanisms and potential cytoskeletal targets have been implicated in vascular endothelial barrier dysfunction; however, the immediate downstream effectors of Ca(2+) signals in the regulation of endothelial permeabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c986007fdeb7b246c507d79dd4ff58c
https://doi.org/10.1074/jbc.m110.120790
https://doi.org/10.1074/jbc.m110.120790
Publikováno v:
Journal of Biological Chemistry. 285:19173-19183
Store-operated calcium (Ca2+) entry (SOCE) mediated by STIM/Orai proteins is a ubiquitous pathway that controls many important cell functions including proliferation and migration. STIM proteins are Ca2+ sensors in the endoplasmic reticulum and Orai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8bb0dcc2aaedc0579dd5ec9b73affe2
https://doi.org/10.1074/jbc.m110.102582
https://doi.org/10.1074/jbc.m110.102582
Autor:
Jose C. Gonzalez, Rajender K. Motiani, Harold A. Singer, Jonathan M. Bisaillon, Marie Potier, Mohamed Trebak, Iskandar F. Abdullaev
Publikováno v:
The FASEB Journal. 23:2425-2437
The identity of store-operated calcium (Ca(2+)) entry (SOCE) channels in vascular smooth muscle cells (VSMCs) remains a highly contentious issue. Whereas previous studies have suggested that SOCE in VSMCs is mediated by the nonselective transient rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaac9aba9cc60b117e37f3bb52d338ea
https://doi.org/10.1096/fj.09-131128
https://doi.org/10.1096/fj.09-131128
Autor:
Mohamed Trebak, Marie Potier, Jose C. Gonzalez, Jonathan M. Bisaillon, Iskandar F. Abdullaev, Rajender K. Motiani
Publikováno v:
Circulation Research. 103:1289-1299
Recent breakthroughs in the store-operated calcium (Ca 2+ ) entry (SOCE) pathway have identified Stim1 as the endoplasmic reticulum Ca 2+ sensor and Orai1 as the pore forming subunit of the highly Ca 2+ -selective CRAC channel expressed in hematopoie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f74652775e33a3cec5f566cf7bd71c
https://doi.org/10.1161/01.res.0000338496.95579.56
https://doi.org/10.1161/01.res.0000338496.95579.56
Publikováno v:
Journal of Neurochemistry. 106:2449-2462
Microglia are the resident immune cells of the CNS, which are important for preserving neural tissue functions, but may also contribute to neurodegeneration. Activation of these cells in infection, inflammation, or trauma leads to the release of vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7a8354e1bbab6870ec7ab42b7a8f92
https://doi.org/10.1111/j.1471-4159.2008.05553.x
https://doi.org/10.1111/j.1471-4159.2008.05553.x
Autor:
Alexander A. Mongin, Harold K. Kimelberg, Gary P. Schools, Alena Rudkouskaya, Iskandar F. Abdullaev
Publikováno v:
The Journal of Physiology. 572:677-689
Ubiquitously expressed volume-regulated anion channels (VRACs) are chloride channels which are permeable to a variety of small organic anions, including the excitatory amino acids (EAAs) glutamate and aspartate. Broad spectrum anion channel blockers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::896ebb9dd8685968a176354913697810
https://doi.org/10.1113/jphysiol.2005.103820
https://doi.org/10.1113/jphysiol.2005.103820
Autor:
F. Anthony Lai, Qi-Bing Mei, Michael I. Kotlikoff, Yong-Xiao Wang, Yun-Min Zheng, Qing-Song Wang, Iskandar F. Abdullaev, Hongbo Xin
Publikováno v:
Cell Calcium. 35:345-355
The cellular and molecular processes underlying the regulation of ryanodine receptor (RyR) Ca 2+ release in smooth muscle cells (SMCs) are incompletely understood. Here we show that FKBP12.6 proteins are expressed in pulmonary artery (PA) smooth musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c136eb93a2f4d0a587cee991350626f
https://doi.org/10.1016/j.ceca.2003.09.006
https://doi.org/10.1016/j.ceca.2003.09.006