Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Isis E. Fernandez"'
Autor:
Jianlong Jia, Lilith Trassl, Fanli Kong, Benteng Deng, Ruonan Liu, Zhengwu Sun, Xiaoyan Lan, Ali Ö. Yildirim, Georgios T. Stathopoulos, Isis E. Fernandez, Andrea C. Schamberger
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102070- (2024)
Introduction: : Small cell lung cancer (SCLC) is mostly diagnosed in stage III-IV patients and associated with poor prognosis. To date, surgery is no gold-standard treatment for any SCLC stage and evidence is lacking whether it is beneficial. Here we
Externí odkaz:
https://doaj.org/article/cfee9fe7b94f4474b973c1f7359be2fc
Autor:
David S. Fischer, Meshal Ansari, Karolin I. Wagner, Sebastian Jarosch, Yiqi Huang, Christoph H. Mayr, Maximilian Strunz, Niklas J. Lang, Elvira D’Ippolito, Monika Hammel, Laura Mateyka, Simone Weber, Lisa S. Wolff, Klaus Witter, Isis E. Fernandez, Gabriela Leuschner, Katrin Milger, Marion Frankenberger, Lorenz Nowak, Katharina Heinig-Menhard, Ina Koch, Mircea G. Stoleriu, Anne Hilgendorff, Jürgen Behr, Andreas Pichlmair, Benjamin Schubert, Fabian J. Theis, Dirk H. Busch, Herbert B. Schiller, Kilian Schober
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
High resolution characterisation of the virus specific T cell response to SARS CoV2 provides further understanding to the immune response to the infection. Here the authors apply a reverse phenotyping approach to interrogate the SARS-CoV-2 T cell com
Externí odkaz:
https://doaj.org/article/84508b147f414165a4d89699fa0e872a
Autor:
Carolina Ballester-López, Thomas M. Conlon, Zeynep Ertüz, Flavia R. Greiffo, Martin Irmler, Stijn E. Verleden, Johannes Beckers, Isis E. Fernandez, Oliver Eickelberg, Ali Önder Yildirim
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 562-575 (2019)
Background: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide with no curative therapy. A non-canonical Notch ligand, DNER, has been recently identified in GWAS to associate with COPD severity, but its functio
Externí odkaz:
https://doaj.org/article/17de654a891c42d38950f3b88bf49d6f
Autor:
Ilias Angelidis, Lukas M. Simon, Isis E. Fernandez, Maximilian Strunz, Christoph H. Mayr, Flavia R. Greiffo, George Tsitsiridis, Meshal Ansari, Elisabeth Graf, Tim-Matthias Strom, Monica Nagendran, Tushar Desai, Oliver Eickelberg, Matthias Mann, Fabian J. Theis, Herbert B. Schiller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Aging impacts lung functionality and makes it more susceptible to chronic diseases. Combining proteomics and single cell transcriptomics, the authors chart molecular and cellular changes in the aging mouse lung, discover aging hallmarks, and predict
Externí odkaz:
https://doaj.org/article/e8bbc178370d42f0a7884140d62b6b59
Autor:
Stefan Preisendörfer, Yoshihiro Ishikawa, Elisabeth Hennen, Stephan Winklmeier, Jonas C. Schupp, Larissa Knüppel, Isis E. Fernandez, Leonhard Binzenhöfer, Andrew Flatley, Brenda M. Juan-Guardela, Clemens Ruppert, Andreas Guenther, Marion Frankenberger, Rudolf A. Hatz, Nikolaus Kneidinger, Jürgen Behr, Regina Feederle, Aloys Schepers, Anne Hilgendorff, Naftali Kaminski, Edgar Meinl, Hans Peter Bächinger, Oliver Eickelberg, Claudia A. Staab-Weijnitz
Publikováno v:
Cells, Vol 11, Iss 8, p 1341 (2022)
Antibodies are central effectors of the adaptive immune response, widespread used therapeutics, but also potentially disease-causing biomolecules. Antibody folding catalysts in the plasma cell are incompletely defined. Idiopathic pulmonary fibrosis (
Externí odkaz:
https://doaj.org/article/eee505bfb71a48c3bf92f6658efc3879
Publikováno v:
European Respiratory Review, Vol 26, Iss 145 (2017)
Fibrotic lung diseases involve subject–environment interactions, together with dysregulated homeostatic processes, impaired DNA repair and distorted immune functions. Systems medicine-based approaches are used to analyse diseases in a holistic mann
Externí odkaz:
https://doaj.org/article/cc080ba96c3f4f6a9217242a80e452cc
Autor:
Axel Walch, Sabina Berezowska, Oliver Eickelberg, Ralph A. Schmid, Michaela Aichler, Danny Jonigk, Maximilian Ackermann, Wim Wuyts, Isis E. Fernandez, Marco Matzka, Annette Feuchtinger, Na Sun, Achim Buck, Verena M. Prade, Thomas Kunzke
Asymptomatic anthracosis is the accumulation of black carbon particles in adult human lungs. It is a common occurrence, but the pathophysiologic significance of anthracosis is debatable. Using in situ high mass resolution matrix-assisted laser desorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49624f4afe1ea6a9c901d386d11b2d81
https://doi.org/10.1158/0008-5472.c.6513588.v1
https://doi.org/10.1158/0008-5472.c.6513588.v1
Autor:
Axel Walch, Sabina Berezowska, Oliver Eickelberg, Ralph A. Schmid, Michaela Aichler, Danny Jonigk, Maximilian Ackermann, Wim Wuyts, Isis E. Fernandez, Marco Matzka, Annette Feuchtinger, Na Sun, Achim Buck, Verena M. Prade, Thomas Kunzke
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4c45574aa1b5c36e58d7f5f6384e4d
https://doi.org/10.1158/0008-5472.22430292
https://doi.org/10.1158/0008-5472.22430292
Autor:
Xinyuan Wang, Huabin Zhang, Yuqin Wang, Laylan Bramasole, Kai Guo, Fatima Mourtada, Thomas Meul, Qianjiang Hu, Valeria Viteri, Ilona Kammerl, Melanie Konigshoff, Mareike Lehmann, Thomas Magg, Fabian Hauck, Isis E Fernandez, Silke Meiners
Publikováno v:
The EMBO Journal. 42
Autocrine Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts
Autor:
Christoph H. Mayr, Arunima Sengupta, Meshal Ansari, Jeanine C. Pestoni, Paulina Ogar, Ilias Angelidis, Andreas Liontos, Alberto Rodriguez-Castillo, Niklas J. Lang, Maximilian Strunz, Sara Asgharpour, Diana Porras-Gonzalez, Michael Gerckens, Bettina Oehrle, Valeria Viteri-Alvarez, Isis E. Fernandez, Michelle Tallquist, Martin Irmler, Johannes Beckers, Oliver Eickelberg, Gabriel Mircea Stoleriu, Jürgen Behr, Nikolaus Kneidinger, Ali Önder Yildirim, Katrin Ahlbrecht, Rory E. Morty, Christos Samakovlis, Fabian J. Theis, Gerald Burgstaller, Herbert B. Schiller
Fibroblast to myofibroblast conversion is a major driver of tissue remodeling in organ fibrosis. Several distinct lineages of fibroblasts support homeostatic tissue niche functions, yet, specific activation states and phenotypic trajectories of fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a71ef4386bf9ba8425663fdc42b3b85
https://doi.org/10.1101/2022.07.11.499594
https://doi.org/10.1101/2022.07.11.499594