Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Isis E Fernandez"'
Autor:
Nora Semren, Nunja C Habel-Ungewitter, Isis E Fernandez, Melanie Königshoff, Oliver Eickelberg, Tobias Stöger, Silke Meiners
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136188 (2015)
Proteasome inhibition has been shown to prevent development of fibrosis in several organs including the lung. However, effects of proteasome inhibitors on lung fibrosis are controversial and cytotoxic side effects of the overall inhibition of proteas
Externí odkaz:
https://doaj.org/article/1a35a94c07044918bd195f58e255d1d3
Autor:
Jianlong Jia, Lilith Trassl, Fanli Kong, Benteng Deng, Ruonan Liu, Zhengwu Sun, Xiaoyan Lan, Ali Ö. Yildirim, Georgios T. Stathopoulos, Isis E. Fernandez, Andrea C. Schamberger
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102070- (2024)
Introduction: : Small cell lung cancer (SCLC) is mostly diagnosed in stage III-IV patients and associated with poor prognosis. To date, surgery is no gold-standard treatment for any SCLC stage and evidence is lacking whether it is beneficial. Here we
Externí odkaz:
https://doaj.org/article/cfee9fe7b94f4474b973c1f7359be2fc
Autor:
Carolina Ballester-López, Thomas M. Conlon, Zeynep Ertüz, Flavia R. Greiffo, Martin Irmler, Stijn E. Verleden, Johannes Beckers, Isis E. Fernandez, Oliver Eickelberg, Ali Önder Yildirim
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 562-575 (2019)
Background: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide with no curative therapy. A non-canonical Notch ligand, DNER, has been recently identified in GWAS to associate with COPD severity, but its functio
Externí odkaz:
https://doaj.org/article/17de654a891c42d38950f3b88bf49d6f
Autor:
Stefan Preisendörfer, Yoshihiro Ishikawa, Elisabeth Hennen, Stephan Winklmeier, Jonas C. Schupp, Larissa Knüppel, Isis E. Fernandez, Leonhard Binzenhöfer, Andrew Flatley, Brenda M. Juan-Guardela, Clemens Ruppert, Andreas Guenther, Marion Frankenberger, Rudolf A. Hatz, Nikolaus Kneidinger, Jürgen Behr, Regina Feederle, Aloys Schepers, Anne Hilgendorff, Naftali Kaminski, Edgar Meinl, Hans Peter Bächinger, Oliver Eickelberg, Claudia A. Staab-Weijnitz
Publikováno v:
Cells, Vol 11, Iss 8, p 1341 (2022)
Antibodies are central effectors of the adaptive immune response, widespread used therapeutics, but also potentially disease-causing biomolecules. Antibody folding catalysts in the plasma cell are incompletely defined. Idiopathic pulmonary fibrosis (
Externí odkaz:
https://doaj.org/article/eee505bfb71a48c3bf92f6658efc3879
Autor:
Axel Walch, Sabina Berezowska, Oliver Eickelberg, Ralph A. Schmid, Michaela Aichler, Danny Jonigk, Maximilian Ackermann, Wim Wuyts, Isis E. Fernandez, Marco Matzka, Annette Feuchtinger, Na Sun, Achim Buck, Verena M. Prade, Thomas Kunzke
Asymptomatic anthracosis is the accumulation of black carbon particles in adult human lungs. It is a common occurrence, but the pathophysiologic significance of anthracosis is debatable. Using in situ high mass resolution matrix-assisted laser desorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49624f4afe1ea6a9c901d386d11b2d81
https://doi.org/10.1158/0008-5472.c.6513588.v1
https://doi.org/10.1158/0008-5472.c.6513588.v1
Autor:
Axel Walch, Sabina Berezowska, Oliver Eickelberg, Ralph A. Schmid, Michaela Aichler, Danny Jonigk, Maximilian Ackermann, Wim Wuyts, Isis E. Fernandez, Marco Matzka, Annette Feuchtinger, Na Sun, Achim Buck, Verena M. Prade, Thomas Kunzke
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4c45574aa1b5c36e58d7f5f6384e4d
https://doi.org/10.1158/0008-5472.22430292
https://doi.org/10.1158/0008-5472.22430292
Autor:
Xinyuan Wang, Huabin Zhang, Yuqin Wang, Laylan Bramasole, Kai Guo, Fatima Mourtada, Thomas Meul, Qianjiang Hu, Valeria Viteri, Ilona Kammerl, Melanie Konigshoff, Mareike Lehmann, Thomas Magg, Fabian Hauck, Isis E Fernandez, Silke Meiners
Publikováno v:
The EMBO Journal. 42
Publikováno v:
European Respiratory Review, Vol 26, Iss 145 (2017)
Fibrotic lung diseases involve subject–environment interactions, together with dysregulated homeostatic processes, impaired DNA repair and distorted immune functions. Systems medicine-based approaches are used to analyse diseases in a holistic mann
Externí odkaz:
https://doaj.org/article/cc080ba96c3f4f6a9217242a80e452cc
Autocrine Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts
Autor:
Christoph H. Mayr, Arunima Sengupta, Meshal Ansari, Jeanine C. Pestoni, Paulina Ogar, Ilias Angelidis, Andreas Liontos, Alberto Rodriguez-Castillo, Niklas J. Lang, Maximilian Strunz, Sara Asgharpour, Diana Porras-Gonzalez, Michael Gerckens, Bettina Oehrle, Valeria Viteri-Alvarez, Isis E. Fernandez, Michelle Tallquist, Martin Irmler, Johannes Beckers, Oliver Eickelberg, Gabriel Mircea Stoleriu, Jürgen Behr, Nikolaus Kneidinger, Ali Önder Yildirim, Katrin Ahlbrecht, Rory E. Morty, Christos Samakovlis, Fabian J. Theis, Gerald Burgstaller, Herbert B. Schiller
Fibroblast to myofibroblast conversion is a major driver of tissue remodeling in organ fibrosis. Several distinct lineages of fibroblasts support homeostatic tissue niche functions, yet, specific activation states and phenotypic trajectories of fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a71ef4386bf9ba8425663fdc42b3b85
https://doi.org/10.1101/2022.07.11.499594
https://doi.org/10.1101/2022.07.11.499594
Autor:
Valeria Viteri-Alvarez, Flavia R. Greiffo, Apurva Dhavale, Daniela Dietel, Marion Frankenberger, Oliver Eickelberg, Juergen Behr, Isis E. Fernandez
Publikováno v:
Idiopathic interstitial pneumonias.