Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Isik Kantarcioglu"'
Autor:
Isik Kantarcioglu, Ilona K. Gaszek, Tandac F. Guclu, M. Sadik Yildiz, Ali Rana Atilgan, Erdal Toprak, Canan Atilgan
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Efflux-mediated β-lactam resistance is a major public health concern, reducing the effectiveness of β-lactam antibiotics against many bacteria. Structural analyses show the efflux protein TolC in Gram-negative bacteria acts as a channel fo
Externí odkaz:
https://doaj.org/article/71075e17eac44e9d81e5283f7576a9b9
Autor:
Ilona K. Gaszek, Isik Kantarcioglu, M. Sadik Yildiz, Levent Sari, Ayesha Ahmed, Alan Katz, Milo M. Lin, Erdal Toprak
Publikováno v:
Biophysical Journal. 122:21a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb2fa3f9eecd92ab92fd3ab1bfbd5f26
https://doi.org/10.1016/j.bpj.2022.11.339
https://doi.org/10.1016/j.bpj.2022.11.339
Publikováno v:
Biophysical Journal. 122:59a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b38f37e9f164b7bffb247f37e8019fdc
https://doi.org/10.1016/j.bpj.2022.11.527
https://doi.org/10.1016/j.bpj.2022.11.527
Autor:
George Liapakis, Sara Alkhatib, Yavuz Ergun, Berfu Nur Yigit, Gülay Bulut, Melih Acar, Busecan Aksoydan, Ismail Erol, Ramin Ekhteiari Salmas, Bahar Kurt, Vlasios Karageorgos, Turker Kilic, Isik Kantarcioglu, Kutay Cantasir, Serdar Durdagi, Gizem Turan, Timuçin Avşar, Barış Sergi
Publikováno v:
European Journal of Medicinal Chemistry. 145:273-290
AT1 antagonists is the most recent drug class of molecules against hypertension and they mediate their actions through blocking detrimental effects of angiotensin II (A-II) when acts on type I (AT1) A-II receptor. The effects of AT1 antagonists are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08fe56a07c296e06a0ef5b2e96481ab
https://doi.org/10.1016/j.ejmech.2017.12.021
https://doi.org/10.1016/j.ejmech.2017.12.021
Autor:
Serdar Durdagi, Matthias Stein, Busecan Aksoydan, Philip Seeman, Ramin Ekhteiari Salmas, Mine Yurtsever, Isik Kantarcioglu, Ismail Erol
Publikováno v:
ACS Chemical Neuroscience
Dopamine receptor D2 (D2R) plays an important role in the human central nervous system and is a focal target of antipsychotic agents. The D2HighR and D2LowR dimeric models previously developed by our group are used to investigate the prediction of bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcf2a8836eafc583c9e9045e3ecc758
https://doi.org/10.1021/acschemneuro.7b00070
https://doi.org/10.1021/acschemneuro.7b00070
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1824
G protein-coupled receptors (GPCRs) represent the biggest class of membrane proteins included in signal transduction cascade across the biological lipid bilayers. They are essential target structures for cell signaling and are of great commercial int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a40176dc94c8e1a2cd2fc3ab8d5e358
https://pubmed.ncbi.nlm.nih.gov/30039423
https://pubmed.ncbi.nlm.nih.gov/30039423
Publikováno v:
Neuroscience letters. 700
G Protein-Coupled Receptors (GPCRs) can form homo- and heterodimers or constitute higher oligomeric clusters with other heptahelical GPCRs. In this article, multiscale molecular modeling approaches as well as experimental techniques which are used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7d201ac7aadc60e7e493f237b751e5
https://pubmed.ncbi.nlm.nih.gov/29684528
https://pubmed.ncbi.nlm.nih.gov/29684528
Publikováno v:
Methods in Molecular Biology ISBN: 9781493986293
G protein-coupled receptors (GPCRs) represent the biggest class of membrane proteins included in signal transduction cascade across the biological lipid bilayers. They are essential target structures for cell signaling and are of great commercial int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38fdbe42cba79cd2d31c1620f0f84dfd
https://doi.org/10.1007/978-1-4939-8630-9_26
https://doi.org/10.1007/978-1-4939-8630-9_26
Publikováno v:
Cancer Research. 79:4787-4787
Triple-negative breast cancer (TNBC) which constitutes 15-20% of breast cancers, is the most aggressive and chemo-resistant subtype of breast cancer and associated with the highest mortality rates of mortality among all breast cancer subtypes. TNBC i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5186d5f33ff56ccb8ce86494997f06fe
https://doi.org/10.1158/1538-7445.am2019-4787
https://doi.org/10.1158/1538-7445.am2019-4787
Publikováno v:
Journal of molecular graphicsmodelling. 74
The serotonin (5-hydroxytryptamine, 5HT) transporter (SERT) is a member of neurotransmitter sodium symporter (NSS) family, which maintains neurotransmitter by reuptaking 5HT into synapses. Decrease in serotonin concentrations in synaptic clefts have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c929f934943517156b3c0b622d137123
https://pubmed.ncbi.nlm.nih.gov/28499269
https://pubmed.ncbi.nlm.nih.gov/28499269