Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Isidro S Marcos"'
Autor:
Aitor Urosa, Ignacio E Tobal, Ángela P de la Granja, M Carmen Capitán, R F Moro, Isidro S Marcos, Narciso M Garrido, Francisca Sanz, Emilio Calle, David Díez
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192113 (2018)
A novel approach to the production of chiral 1,3-cyclohexadienals has been developed. The organocatalysed asymmetric reaction of different β-disubstituted-α,β-unsaturated aldehydes with a chiral α,β-unsaturated aldehyde in the presence of a Jør
Externí odkaz:
https://doaj.org/article/74c0bd6235c94cbb88c132080f7fe834
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
The development of new anti-cancer agents is an urgent necessity nowadays, as it is one of the major causes of mortality worldwide. Many drugs currently used are derived from natural products. Halimanes are a class of bicyclic diterpenoids present in
Externí odkaz:
https://doaj.org/article/28869f3e716b451884e2ed44b57ece13
Publikováno v:
Chiral Building Blocks in Asymmetric Synthesis. :267-296
Autor:
Javier Peña, Gastón Silveira-Dorta, Rosalina F. Moro, Narciso M. Garrido, Isidro S. Marcos, Francisca Sanz, David Díez
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 6409-6418 (2015)
The first organocatalytic synthesis of cis-decalins using sulfonyl Nazarov reagents is reported. The Jørgensen’s catalyst directs this highly enantioselective synthesis using different cyclohexenal derivatives.
Externí odkaz:
https://doaj.org/article/f6efc60ec10c485fb6c94d36702a825a
Autor:
Aitor Urosa, Isidro S. Marcos, David Díez, Anna Lithgow, Gabriela B. Plata, José M. Padrón, Pilar Basabe
Publikováno v:
Marine Drugs, Vol 13, Iss 4, Pp 2407-2423 (2015)
The first synthesis of Luffarin I, sesterterpenolide isolated from sponge Luffariella geometrica, has been accomplished from commercially available sclareol. The key strategy involved in this synthesis is the diastereoselective reduction of an interm
Externí odkaz:
https://doaj.org/article/3cda19a8e89242b5af5add8d57c678f4
Autor:
Pilar García, Enrique F. Iglesias, Isidro S. Marcos, Narciso M. Garrido, Rosalina F. Moro, Marta G. Núñez, Mari Fe. Flores, David Díez
Publikováno v:
Molecules, Vol 15, Iss 3, Pp 1501-1512 (2010)
The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronolactol as a suitable starting material.
Externí odkaz:
https://doaj.org/article/199e6f74cc0b49bbb6ef4a34d6fd2678
Publikováno v:
Molecules, Vol 25, Iss 1707, p 1707 (2020)
Molecules
Molecules
The development of new agents against bacteria is an urgent necessity for human beings. The structured colony of bacterial cells, called the biofilm, is used to defend themselves from biocide attacks. For this reason, it is necessary to know their st
Autor:
Ana Gil-Mesón, Alejandro M. Roncero, Ignacio E. Tobal, Pilar Basabe, David Díez, Faustino Mollinedo, Isidro S. Marcos
Publikováno v:
Molecules, Vol 21, Iss 1, p 47 (2015)
A series of sesterterpenoid bioconjugates with phospholipids and polyunsaturated fatty acids (PUFAs) have been synthesized for biological activity testing as antiproliferative agents in several cancer cell lines. Different substitution analogues of t
Externí odkaz:
https://doaj.org/article/cf6616c135e24765bcc6829acbd51348
Autor:
Ignacio E, Tobal, Lourdes, Castañeda, Alejandro M, Roncero, Rosalina F, Moro, David, Diez, Isidro S, Marcos
Publikováno v:
Natural product communications. 12(5)
Sclareol has been employed as starting material for the synthesis of several advanced intermediates towards the synthesis of highly ring B oxygenated labdanes. Dinorlabdanes 6,7,8,9-tetraoxygenated with 6,7-dioxygenated functionalities with a-cis or
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 73, Iss 1, Pp 85-87 (2017)
The title compound, C12H15NO3S, was prepared by 1,3-dipolar cycloaddition of 3,4-dihydro-2H-pyrrole 1-oxide and phenyl vinyl sulfone. In the molecule, both fused five-membered rings display a twisted conformation. In the crystal, C—H...O hydrogen b